Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Glenn Wozniak"'
Autor:
Tuancheng Feng, Gregory Minevich, Pengan Liu, Henry Xin Qin, Glenn Wozniak, Jenny Pham, Khanh Pham, Akshata Korgaonkar, Michael Kurnellas, Nadine A. Defranoux, Hua Long, Ananya Mitra, Fenghua Hu
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107247- (2023)
Summary: Loss of function of progranulin (PGRN), encoded by the granulin (GRN) gene, is implicated in several neurodegenerative diseases. Several therapeutics to boost PGRN levels are currently in clinical trials. However, it is difficult to test the
Externí odkaz:
https://doaj.org/article/5c58363b9fdc45cf85a9ac0f148daac3
Autor:
Yonglu Che, Zurab Siprashvili, Joanna R. Kovalski, Tiffany Jiang, Glenn Wozniak, Lara Elcavage, Paul A. Khavari
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Small nucleolar RNAs, SNORD50A/B are frequently deleted in cancers and can inhibit KRAS but by unclear means. Here, the authors show that KRAS trafficking and enrichment on the plasma membrane is mediated by SNARE vesicle transport proteins and that
Externí odkaz:
https://doaj.org/article/b685d23387bf46fe8aee5ef2775003e5
Autor:
Darcy W, Holley, Beezly S, Groh, Glenn, Wozniak, Dallas R, Donohoe, Wei, Sun, Virginia, Godfrey, Scott J, Bultman
Publikováno v:
Journal of cellular physiology. 229(1)
Widespread changes in gene expression underlie B cell development and activation, yet our knowledge of which chromatin-remodeling factors are essential is limited. Here, we demonstrate that the BRG1 catalytic subunit of SWI/SNF complexes was dispensa