In vivo magnetic resonance studies reveal neuroanatomical and neurochemical abnormalities in the serine racemase knockout mouse model of schizophrenia

Autor: Matthew D. Puhl, Dionyssios Mintzopoulos, J. Eric Jensen, Timothy E. Gillis, Glenn T. Konopaske, Marc J. Kaufman, Joseph T. Coyle

Publikováno v: Neurobiology of Disease, Vol 73, Iss , Pp 269-274 (2015)

Background: Decreased availability of the N-methyl-d-aspartate receptor (NMDAR) co-agonist d-serine is thought to promote NMDAR hypofunction and contribute to the pathophysiology of schizophrenia, including neuroanatomical abnormalities, such as cort

Externí odkaz: https://doaj.org/article/b0c84b33fdb845c997d70d930be07d76

Contributors

Autor: Samira Abdulai-Saiku, Stanley H. Appel, Arthur P. Arnold, Lisa M. Arnold, Robert M. Arnold, Alexa Bacha, Miroslav 'Misha' Backonja, Zinzi D. Bailey, Lucinda Bateman, David R. Beers, Anna Berti, Mamta Bhatnagar, Devin K. Binder, Marina Boido, Maura Boldrini, David Borsook, Xandra O. Breakefield, Robert H. Brown, Rami Burstein, Eduardo R. Butelman, Louis R. Caplan, S. Chen, Marie-Françoise Chesselet, Stefan Clemens, Paula R. Clemens, Joseph T. Coyle, John C. DeWitt, Dena B. Dubal, Veljko Dubljević, Eva L. Feldman, Beth A. Fischer, M.C. Flux, J.S. Fortin, Angelisa Frasca, Francesca Garbarini, Thomas Gasser, Charles F. Gillespie, Michael S. Gold, Stefan M. Gold, Randi Hagerman, Regan Hamel, Craig Haney, James C. Harris, Sara Hassani, Norman J. Haughey, Vibol Heng, J. Horn, Rosana-Bristena Ionescu, Raffaele Iorio, David J. Irwin, Henry J. Kaminski, Dalia Khammash, Vikram Khurana, Charlotte Kilstrup-Nielsen, Bhumsoo Kim, Boram Kim, Marieke Klein, Nastassja Koen, Glenn T. Konopaske, Joanna A. Korecka, Birgitte Rahbek Kornum, Mary Jeanne Kreek, Krister Kristensson, Grzegorz Krzak, Linda L. Kusner, Nicoletta Landsberger, Edward B. Lee, Tong Li, Paweł P. Liberski, Christine Lochner, Christopher A. Lowry, J. John Mann, Clara Marincowitz, E.A. Mayer, E.D. Mayer, Iris Coates McCall, Louise D. McCullough, Michael J. Meaney, Claudio Melo de Gusmao, Abhishek L. Menesgere, Emmanuel Mignot, William C. Mobley, Mayra Montalvo, Alisha R. Moreland-Capuia, Marco Neppi-Modona, Alexandra M. Nicaise, Rae Nishi, Orna O'Toole, Cassia Overk, Laurie Ozelius, Matthew P. Parsons, H.B. Penticoff, Luca Peruzzotti-Jametti, Owen M. Peters, Allison Peterson, Jessica M. Phan, Sean J. Pittock, Stefano Pluchino, Thad A. Polk, Araya Puwanant, Shreya K. Rajagopal, Vijayalakshmi Ravindranath, Lynn A. Raymond, Brian Reed, Kerry J. Ressler, Diane L. Ritchie, Leah H. Rubin, Stacey A. Sakowski, Mario A. Saporta, Alena V. Savonenko, Helen E. Scharfman, Bruce K. Shapiro, Nutan Sharma, Cayce K. Shaw, Michael E. Shy, Beata Sikorska, Ethan J. Silverman, Roger P. Simon, Kristina Simonyan, Catrina Sims-Robinson, Richard Jay Smeyne, Clay Smith, Colin Smith, Sharan R. Srinivasan, Dan J. Stein, Christopher D. Stephen, Indu Subramanian, Edina Szabo, Alissa A. Thomas, Luis B. Tovar-y-Romo, Arshya Vahabzadeh, Alessandro Vercelli, Ashley Viera-Ortiz, Mitchell T. Wallin, Donna M. Werling, Thomas Wichmann, Clayton A. Wiley, David R. Williams, Cory Willis, Philip C. Wong, Vadim Yuferov, Weihua Zhao, Michael J. Zigmond, Saša A. Živković

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::243fdcc9a4e15e7cb9744b08ed648667
https://doi.org/10.1016/b978-0-323-85654-6.01002-9

Dysbindin-1 contributes to prefrontal cortical dendritic arbor pathology in schizophrenia

Autor: Darrick T. Balu, Glenn T. Konopaske, Joseph T. Coyle, Grace Chan, Kendall Taylor Presti, Francine M. Benes

Publikováno v: Schizophrenia Research. 201:270-277

Deep layer III pyramidal cells in the dorsolateral prefrontal cortex (DLPFC) from subjects with schizophrenia and bipolar disorder previously were shown to exhibit dendritic arbor pathology. This study sought to determine whether MARCKS, its regulato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8241aacec4d7fb4c75db07f4b6aad0f9
https://doi.org/10.1016/j.schres.2018.04.042

Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis

Autor: Fumio Nakamura, Husseini K. Manji, Namrata D. Udeshi, Hagop S. Akiskal, Jeffrey H. Price, Nikolaos Venizelos, Wen-Ning Zhao, Cordulla Duerr, Ryan W. Logan, Jeffrey S. Nye, Jasmin Lalonde, Steven D. Sheridan, Joseph T. Coyle, Toshio Ohshima, Yoshio Goshima, Michael McCarthy, Shelley Halpain, Barbara Calabrese, Joshua G. Hunsberger, Martin Alda, Yuuka Inoue, Gustavo J. Gutierrez, Stephen J. Haggarty, Brian T. D. Tobe, Cameron D. Pernia, Richard L. Sidman, Moyuka Wada, Hiroko Makihara, Laurence M. Brill, Glenn T. Konopaske, Yang Liu, De-Maw M. Chuang, Ranor C. B. Basa, Alicia M. Winquist, Yang D. Teng, Michelle M. Sidor, Steven A. Carr, Colleen A. McClung, Guy A. Rouleau, Katsuhiko Mikoshiba, Evan Y. Snyder, Laurel Dorsett, Lina Mastrangelo, Guang Chen, Jianxue Li, Haruko Nakamura, Andrew Crain, Philipp Mertins, Michael G. Brandel, Dongmei Wu, Naoya Yamashita

Publikováno v: Publikationer från Örebro universitet.

The molecular pathogenesis of bipolar disorder (BPD) is poorly understood. Using human-induced pluripotent stem cells (hiPSCs) to unravel such mechanisms in polygenic diseases is generally challenging. However, hiPSCs from BPD patients responsive to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af943d65b2b76fb0f4b555e7351a2c67
http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-57888

Catatonia in Psychotic Patients: Clinical Features and Treatment Response

Autor: Mary Lou England, Dost Öngür, Glenn T. Konopaske, Rakesh Karmacharya

Publikováno v: The Journal of Neuropsychiatry and Clinical Neurosciences. 23:223-226

The authors report clinical features and treatment response in 25 patients with catatonia admitted to an inpatient psychiatric unit specializing in psychotic disorders. Electroconvulsive therapy, benzodiazepines, and clozapine had beneficial effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ff7c53d8c208a85f98b54b6adde6e7
https://doi.org/10.1176/jnp.23.2.jnp223