Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Glenn S. Belinsky"'
Autor:
Glenn S. Belinsky, Matthew T. Rich, Carissa L. Sirois, Shaina M. Short, Erika Pedrosa, Herbert M. Lachman, Srdjan D. Antic
Publikováno v:
Stem Cell Research, Vol 12, Iss 1, Pp 101-118 (2014)
Molecular genetic studies are typically performed on homogenized biological samples, resulting in contamination from non-neuronal cells. To improve expression profiling of neurons we combined patch recordings with single-cell PCR. Two iPSC lines (hea
Externí odkaz:
https://doaj.org/article/bbc10efbf2db495eb0699af9890da55c
Autor:
Glenn S. Belinsky, Srdjan D. Antic
Publikováno v:
BioTechniques, Vol 55, Iss 2, Pp 79-82 (2013)
Culture of pluripotent stem cells at 35°C strikingly reduces unwanted spontaneous differentiation during hESC and iPSC maintenance compared with 37°C. Growth at 35°C did not affect expression of pluripotency mRNAs nor induce expression of cold-ind
Externí odkaz:
https://doaj.org/article/eebe649c81c34106b22575559ebcc38e
Autor:
Petr Protiva, Jingjing Gong, Bharath Sreekumar, Richard Torres, Xuchen Zhang, Glenn S. Belinsky, Mona Cornwell, Susan E. Crawford, Yasuko Iwakiri, Chuhan Chung
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 5, Pp 535-549.e14 (2015)
Background & Aims: Pigment epithelium-derived factor (PEDF) is a secretory protein that inhibits multiple tumor types. PEDF inhibits the Wnt coreceptor, low-density lipoprotein receptor-related protein 6 (LRP6), in the eye, but whether the tumor-supp
Externí odkaz:
https://doaj.org/article/9d414f0e15fb492d9365197a7d29d708
Publikováno v:
Journal of Biological Chemistry. 291:22074-22085
An increase in autophagy characterizes pancreatic carcinogenesis, but the signals that regulate this process are incompletely understood. Because canonical Wnt/β-catenin signaling is necessary for the transition from early to advanced pancreatic int
Autor:
Jillian W. Andrejecsk, W. Mark Saltzman, Bharath K. Sreekumar, Raimund I. Herzog, Chuhan Chung, Valerie Horsley, Samantha Lin, Thomas O. Carpenter, Jingjing Gong, Glenn S. Belinsky
Publikováno v:
The FASEB Journal. 30:2837-2848
Null mutations in for pigment epithelium-derived factor (PEDF), the protein product of the SERPINF1 gene, are the cause of osteogenesis imperfecta (OI) type VI. The PEDF-knockout (KO) mouse captures crucial elements of the human disease, including di
Autor:
Chuhan Chung, Andrew D. Rhim, Henrik Einwächter, Bharath K. Sreekumar, Roland M. Schmid, Glenn S. Belinsky
Publikováno v:
Pancreas. 43:1256-1263
A functional vacuolar adenosine triphosphatase (v-ATPase) complex regulates canonical Wnt/β-catenin signaling. The goal of this study was to identify the distribution of the v-ATPase in human and murine models of pancreatic intraepithelial neoplasms
Autor:
Erika Pedrosa, Glenn S. Belinsky, Shaina M. Short, Carissa L. Sirois, Srdjan D. Antic, Matthew T. Rich, Herbert M. Lachman
Publikováno v:
Stem Cell Research, Vol 12, Iss 1, Pp 101-118 (2014)
Molecular genetic studies are typically performed on homogenized biological samples, resulting in contamination from non-neuronal cells. To improve expression profiling of neurons we combined patch recordings with single-cell PCR. Two iPSC lines (hea
Autor:
Srdjan D. Antic, Herbert M. Lachman, Michele L. McGovern, Mandakini B. Singh, Pallavi V. Limaye, Katerina D. Oikonomou, Glenn S. Belinsky, Erika Pedrosa
Publikováno v:
Pluripotent Stem Cells-From the Bench to the Clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce527541ea9f1054e4111cf782ea170
https://doi.org/10.5772/62769
https://doi.org/10.5772/62769
Publikováno v:
Rare Diseases
Osteogenesis imperfecta (OI) Type VI is characterized by a defect in bone mineralization, which results in multiple fractures early in life. Null mutations in the PEDF gene, Serpinf1, are the cause of OI VI. Whether PEDF restoration in a murine model
Autor:
Armen H. Tashjian, Glenn S. Belinsky
Publikováno v:
Journal of Bone and Mineral Research. 15:550-556
Previous findings have shown that osteoblasts respond to parathyroid hormone (PTH) with an increase in extracellular acidification rate (ECAR) in addition to the known effect of PTH to increase local acidification by osteoclasts. We, therefore, inves