Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Glenn P Morlock"'
1
Akademický článek
Isolation and identification of mycobacteria from livestock specimens and milk obtained in Brazil
Autor: Clarice Q Fujimura Leite, Ivone S Anno, Sergio R de Andrade Leite, Eliana Roxo, Glenn P Morlock, Robert C Cooksey
Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 98, Iss 3, Pp 319-323 (2003)
The prevalence of Mycobacterium bovis and other mycobacterial species in livestock specimens and milk was evaluated. An emphasis was placed upon the distribution of these organisms in milk that is readily available to the public that was either untre
Externí odkaz: https://doaj.org/article/6d063bfab25943e59dc1099f64501166
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2
Akademický článek
Identifying Mycobacterium species and strain typing using a microfluidic labchip instrument
Autor: Robert C. Cooksey, Josef Limor, Glenn P. Morlock, Jack T. Crawford
Publikováno v: BioTechniques, Vol 35, Iss 4, Pp 786-794 (2003)
We developed schemes for rapid identification of Mycobacterium species and strain typing using a microfluidic labchip instrument. A 439-bp region of the gene that codes for the 65-kDa heat shock protein (hsp65), which has sequence polymorphisms speci
Externí odkaz: https://doaj.org/article/8165f2d362f7447ebb7362d621eae44b
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3
Optimising pyrazinamide for the treatment of tuberculosis
Autor: Marc H Weiner, James E. Posey, Patrick P. J. Phillips, William C. Whitworth, Radojka M. Savic, Erin Bliven-Sizemore, Michael Hoelscher, Rob E. Aarnoutse, Glenn P. Morlock, Kelly E. Dooley, William R. Mac Kenzie, Norbert Heinrich, Martin J. Boeree, Charles A. Peloquin, Nan Zhang, Jason E. Stout
Publikováno v: European Respiratory Journal, 58, 1
Eur Respir J
European Respiratory Journal, 58
Pyrazinamide is a potent sterilising agent that shortens the treatment duration needed to cure tuberculosis. It is synergistic with novel and existing drugs for tuberculosis. The dose of pyrazinamide that optimises efficacy while remaining safe is un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbd540f7064796a5bef319c452b0485
https://doi.org/10.1183/13993003.02013-2020
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4
Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine learning approaches
Autor: Joshua Carter, Tim E. A. Peto, Derrick W. Crook, A. Sarah Walker, Timothy M Walker, Michael G. Whitfield, James E. Posey, Philip W. Fowler, Glenn P. Morlock
Pyrazinamide is one of four first-line antibiotics currently used to treat tuberculosis and has been included in newer treatment regimens undergoing clinical trials due to its unique sterilizing effects and synergy with newer drugs. However, phenotyp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33efb2d3efad2fb176debaf61d0688b
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5
Using Reduced Inoculum Densities of
Autor: Glenn P, Morlock, Frances C, Tyrrell, Dorothy, Baynham, Vincent E, Escuyer, Nicole, Green, Youngmi, Kim, Patricia A, Longley-Olson, Nicole, Parrish, Courtney, Pennington, Desmond, Tan, Brett, Austin, James E, Posey
Publikováno v: Tuberculosis Research and Treatment
The primary platform used for pyrazinamide (PZA) susceptibility testing of Mycobacterium tuberculosis is the MGIT culture system (Becton Dickinson). Since false-resistant results have been associated with the use of this system, we conducted a multic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::75952bf54d18630a80155005466f4af1
https://pubmed.ncbi.nlm.nih.gov/29250443
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6
Using Reduced Inoculum Densities of Mycobacterium tuberculosis in MGIT Pyrazinamide Susceptibility Testing to Prevent False-Resistant Results and Improve Accuracy: A Multicenter Evaluation
Autor: Desmond Tan, Brett Austin, James E. Posey, Patricia A. Longley-Olson, Dorothy Baynham, Nicole M Green, Courtney Pennington, Youngmi Kim, Frances C. Tyrrell, Vincent E. Escuyer, Nicole Parrish, Glenn P. Morlock
Publikováno v: Tuberculosis Research and Treatment, Vol 2017 (2017)
The primary platform used for pyrazinamide (PZA) susceptibility testing of Mycobacterium tuberculosis is the MGIT culture system (Becton Dickinson). Since false-resistant results have been associated with the use of this system, we conducted a multic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae98087beacb6a15dbeac70b6969f054
https://doaj.org/article/28b6c3f847b9490c9b8ab157ba7bb845
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7
Molecular Detection of Mutations Associated with First- and Second-Line Drug Resistance Compared with Conventional Drug Susceptibility Testing of Mycobacterium tuberculosis
Autor: Angela M. Starks, Beverly Metchock, R. David Sikes, Tracy Dalton, Delaina P. Hooks, Bonnie B. Plikaytis, Lauren S. Cowan, James E. Posey, Glenn P. Morlock, Patricia J. Campbell
Publikováno v: Antimicrobial Agents and Chemotherapy. 55:2032-2041
The emergence of multi- and extensively drug-resistant tuberculosis is a significant impediment to the control of this disease because treatment becomes more complex and costly. Reliable and timely drug susceptibility testing is critical to ensure th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a75753b06c737ba8882b702f9deeb4c
https://doi.org/10.1128/aac.01550-10
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9
Mycobacterium cosmeticum sp. nov., a novel rapidly growing species isolated from a cosmetic infection and from a nail salon
Autor: Ismar Rivera, Marina Chopite, Sean R. Toney, Jacobus H. de Waard, W. Ray Butler, Robert C. Cooksey, Glenn P. Morlock, Mitchell A. Yakrus
Publikováno v: International Journal of Systematic and Evolutionary Microbiology. 54:2385-2391
Four isolates of a rapidly growingMycobacteriumspecies had a mycolic acid pattern similar to that ofMycobacterium smegmatis, as determined by HPLC analyses. Three of the isolates were from footbath drains and a sink at a nail salon located in Atlanta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d26aa9f7d898ca1c573b6b15567811
https://doi.org/10.1099/ijs.0.63238-0
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10
Screening and Characterization of Mutations in Isoniazid-Resistant Mycobacterium tuberculosis Isolates Obtained in Brazil
Autor: Maria de Lourdes Shikama, Rosilene Fressatti Cardoso, Clarice Queico Fujimura Leite, Elsa Masae Mamizuka, Rosario Dominguez Crespo Hirata, Daisy Nakamura Sato, Letícia Cecon, Robert C. Cooksey, Glenn P. Morlock, Patricia Barco, Francisco José Forestiero, Mario Hiroyuki Hirata
Publikováno v: Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
We investigated mutations in the genes katG, inhA (regulatory and structural regions), and kasA and the oxyR-ahpC intergenic region of 97 isoniazid (INH)-resistant and 60 INH-susceptible Mycobacterium tuberculosis isolates obtained in two states in B
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17c1215d786602c647de9e98cadc895
https://doi.org/10.1128/aac.48.9.3373-3381.2004
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