Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Glenn Overman"'
Autor:
Akshaya Ramesh, Sam Darko, Axin Hua, Glenn Overman, Amy Ransier, Joseph R. Francica, Ashley Trama, Georgia D. Tomaras, Barton F. Haynes, Daniel C. Douek, Thomas B. Kepler
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The rhesus macaque is a critically important animal model in biomedical research, most recently playing a key role in the development of vaccines against human immunodeficiency virus-1. Nevertheless, the immunoglobulin (Ig) loci of macaques are as ye
Externí odkaz:
https://doaj.org/article/6335464dc6eb4094842e71d419596c78
Autor:
Sheetal Sawant, Sarah Anne Gurley, R. Glenn Overman, Angelina Sharak, Sarah V. Mudrak, Thomas Oguin, Gregory D. Sempowski, Marcella Sarzotti-Kelsoe, Emmanuel B. Walter, Hang Xie, Marcela F. Pasetti, M. Anthony Moody, Georgia D. Tomaras
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionHemagglutination inhibition (HAI) antibody titers to seasonal influenza strains are important surrogates for vaccine-elicited protection. However, HAI assays can be variable across labs, with low sensitivity across diverse viruses due to
Externí odkaz:
https://doaj.org/article/fb09ca27495b4849a863aa424e95e29c
Autor:
Kevin O. Saunders, Nathan I. Nicely, Kevin Wiehe, Mattia Bonsignori, R. Ryan Meyerhoff, Robert Parks, William E. Walkowicz, Baptiste Aussedat, Nelson R. Wu, Fangping Cai, Yusuf Vohra, Peter K. Park, Amanda Eaton, Eden P. Go, Laura L. Sutherland, Richard M. Scearce, Dan H. Barouch, Ruijun Zhang, Tarra Von Holle, R. Glenn Overman, Kara Anasti, Rogier W. Sanders, M. Anthony Moody, Thomas B. Kepler, Bette Korber, Heather Desaire, Sampa Santra, Norman L. Letvin, Gary J. Nabel, David C. Montefiori, Georgia D. Tomaras, Hua-Xin Liao, S. Munir Alam, Samuel J. Danishefsky, Barton F. Haynes
Publikováno v:
Cell Reports, Vol 18, Iss 9, Pp 2175-2188 (2017)
Summary: Induction of broadly neutralizing antibodies (bnAbs) that target HIV-1 envelope (Env) is a goal of HIV-1 vaccine development. A bnAb target is the Env third variable loop (V3)-glycan site. To determine whether immunization could induce antib
Externí odkaz:
https://doaj.org/article/f020d40e9877461f93e8d9d15c7fa9e4
Autor:
Robert Parks, Nelson R. Wu, Thomas B. Kepler, Fangping Cai, Tarra Von Holle, Yusuf Vohra, Bette T. Korber, Georgia D. Tomaras, Mattia Bonsignori, Barton F. Haynes, Samuel J. Danishefsky, M. Anthony Moody, Richard M. Scearce, Amanda Eaton, Eden P. Go, Ruijun Zhang, Hua-Xin Liao, Peter K. Park, Sampa Santra, Dan H. Barouch, Nathan I. Nicely, Heather Desaire, Kevin O. Saunders, R. Ryan Meyerhoff, David C. Montefiori, William E. Walkowicz, Kevin Wiehe, Rogier W. Sanders, Kara Anasti, Gary J. Nabel, R. Glenn Overman, Baptiste Aussedat, S. Munir Alam, Norman L. Letvin, Laura L. Sutherland
Publikováno v:
Cell reports, 18(9), 2175-2188. Cell Press
Cell Reports, Vol 18, Iss 9, Pp 2175-2188 (2017)
Cell Reports, Vol 18, Iss 9, Pp 2175-2188 (2017)
Summary: Induction of broadly neutralizing antibodies (bnAbs) that target HIV-1 envelope (Env) is a goal of HIV-1 vaccine development. A bnAb target is the Env third variable loop (V3)-glycan site. To determine whether immunization could induce antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb437a4f63864a9bba94b8e3b3f33f26
https://doi.org/10.1016/j.celrep.2017.02.003
https://doi.org/10.1016/j.celrep.2017.02.003
Autor:
Vaishnavi Venkat, Guido Ferrari, Derek W. Cain, Georgia D. Tomaras, Barton F. Haynes, R. Whitney Edwards, Yue Chen, Persephone Borrow, Christopher W. Woods, M. Anthony Moody, Myron S. Cohen, Bhavna Hora, Mark Connors, Dapeng Li, R. Glenn Overman, Todd Bradley, Geoffrey S. Ginsburg, Isabela Pedroza-Pacheco, Dimitra Peppa, Ricardo Henao, Nathan Vandergrift
Publikováno v:
Cell
Summary HIV-1 broadly neutralizing antibodies (bnAbs) are difficult to induce with vaccines but are generated in ∼50% of HIV-1-infected individuals. Understanding the molecular mechanisms of host control of bnAb induction is critical to vaccine des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de66eb45e2ec2cc41e651bcfd5d4d51
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Josh A Eudailey, Caroline C. King, Christie Brinkley, Wes Rountree, Denise J. Jamieson, Sascha R. Ellington, Georgia D. Tomaras, Justin Pollara, Guido Ferrari, R. Glenn Overman, Kelly E. Seaton, R. Whitney Edwards, Deborah Kamwendo, Charles van der Horst, Thomas N. Denny, Jacob Kumwenda, Aaron Deal, Gerald Tegha, Sallie R. Permar, Athena P. Kourtis, Genevieve G. Fouda, Julie A. E. Nelson, Hua-Xin Liao, Christina Ochsenbauer, Erin McGuire
Publikováno v:
Journal of Virology. 89:9952-9961
Infants born to HIV-1-infected mothers in resource-limited areas where replacement feeding is unsafe and impractical are repeatedly exposed to HIV-1 throughout breastfeeding. Despite this, the majority of infants do not contract HIV-1 postnatally, ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ddb7b6b471cd76a523ab08739013abc
https://doi.org/10.1128/jvi.01560-15
https://doi.org/10.1128/jvi.01560-15
Autor:
M. Anthony Moody, Joshua D. Amos, Sallie R. Permar, Krista Beck, Lawrence C. Armand, Jonathon E. Himes, David R. Martinez, Thaddeus C. Gurley, Hua-Xin Liao, R. Glenn Overman, Lisa Colvin
Publikováno v:
Journal of Virology. 89:9485-9498
The initial phases of acute human immunodeficiency virus type 1 (HIV-1) infection may be critical for development of effective envelope (Env)-specific antibodies capable of impeding the establishment of the latent pool of HIV-1-infected CD4 + T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e129f3784f917a9f5bf9bcebdce7dccc
https://doi.org/10.1128/jvi.01564-15
https://doi.org/10.1128/jvi.01564-15
Autor:
Fangping Cai, Marcella Sarzotti-Kelsoe, M. Anthony Moody, Shi Mao Xia, David C. Montefiori, Peter B. Gilbert, Robert Parks, Amit Kumar, Emma Friberg, Raul Louzao, Guido Ferrari, Krissey E. Lloyd, Thaddeus C. Gurley, Hua-Xin Liao, Thomas N. Denny, Tarra Von Holle, Youyi Fong, Samantha Wilkes, Dawn J. Marshall, Erika Solomon, Xiaoying Shen, Kaylan Whitaker, Genevieve G. Fouda, David R. Martinez, Frederick H. Jaeger, S. Munir Alam, Saheli Datta, Jamie Pritchett, Brooke E. Liebl, Nathan Vandergrift, Feng Gao, Xiaozhi Lu, Sallie R. Permar, Georgia D. Tomaras, John F. Whitesides, Barton F. Haynes, Amanda Martelli, Nicole L. Yates, Justin Pollara, R. Glenn Overman, Haiyan Chen
Publikováno v:
Journal of Clinical Investigation. 125:2702-2706
Despite the wide availability of antiretroviral drugs, more than 250,000 infants are vertically infected with HIV-1 annually, emphasizing the need for additional interventions to eliminate pediatric HIV-1 infections. Here, we aimed to define humoral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659d3346b6d664a6ac489636aa4e82fb
https://doi.org/10.1172/jci81593
https://doi.org/10.1172/jci81593
Autor:
M. Anthony Moody, Audrey L. French, Kerrie L. McCotter, Thomas J. Hope, Hua-Xin Liao, Nathan Vandergrift, R. Glenn Overman, Pinghuang Liu, Daniel J. Stieh, Barton F. Haynes, Xiaoying Shen, Georgia D. Tomaras, Mattia Bonsignori, Robin J. Shattock, LaTonya D. Williams
Publikováno v:
Journal of Virology. 88:5165-5170
Antibody capacity to recognize infectious virus is a prerequisite of many antiviral functions. We determined the infectious virion capture index (IVCI) of different antibody specificities. Whereas broadly neutralizing antibodies (bNAbs), except for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4a0d62e110f1760ff8a5a5fb4d598c
https://doi.org/10.1128/jvi.03765-13
https://doi.org/10.1128/jvi.03765-13
Autor:
C. Todd DeMarco, Sallie R. Permar, Lisa Colvin, Tatenda Mahlokozera, Celia C. LaBranche, Krista Beck, M. Anthony Moody, Carrie Ho, R. Glenn Overman, Terry L. Hodge, Thomas N. Denny, David C. Montefiori, Andrew B. Wilks, Genevieve G. Fouda, Hua-Xin Liao, Joshua D. Amos, Georgia D. Tomaras, Shannon D. Smith
Publikováno v:
Journal of Virology. 87:11121-11134
The design of an effective vaccine to reduce the incidence of mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) via breastfeeding will require identification of protective immune responses that block postnatal virus acquisitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d424668bd0b159a2db09c093050a14a
https://doi.org/10.1128/jvi.01887-13
https://doi.org/10.1128/jvi.01887-13