Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Glenn Merrill‐Skoloff"'
Autor:
Lin Lin, Da-Yuan Chen, Christina Scartelli, Huanzhang Xie, Glenn Merrill-Skoloff, Moua Yang, Lijun Sun, Mohsan Saeed, Robert Flaumenhaft
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107602- (2023)
Summary: Plant-based flavonoids have been evaluated as inhibitors of β-coronavirus replication and as therapies for COVID-19 on the basis of their safety profile and widespread availability. The SARS-CoV-2 main protease (Mpro) has been implicated as
Externí odkaz:
https://doaj.org/article/39b04371d6844ffb8a5d50a2ddaf2484
Autor:
Anna Gromotowicz‐Poplawska, Robert Flaumenhaft, Shadi K. Gholami, Glenn Merrill‐Skoloff, Ewa Chabielska, Gordon H. Williams, Jose R. Romero
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 22 (2021)
Background In addition to its role on blood pressure, aldosterone (ALDO) also affects the hemostatic system leading to increased experimental thrombosis. Striatin is an intermediate in the rapid, nongenomic actions of ALDO. Striatin heterozygote knoc
Externí odkaz:
https://doaj.org/article/c7748ae1843e444a9499d422550227ff
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
What keeps blood from clotting in homeostasis is a puzzle. Here, the authors suggest that lack of the enzyme disulfide isomerase (PDI) in the blood is key, and show that PDI is secreted only after vascular injury to act on substrates that include vit
Externí odkaz:
https://doaj.org/article/46b7214a18e6426fb3abcf41ea49708f
Autor:
Farha Mithila, Christopher Schwake, Chao Fang, Glenn Merrill-Skoloff, Lidija Covic, Daniel I. Fritz, Toshihiko Hanada, Robert Flaumenhaft, Athar H. Chishti
Publikováno v:
Thromb Res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfc34d43949ab6a11a0f1ebeb4c1517
https://doi.org/10.1016/j.thromres.2022.01.029
https://doi.org/10.1016/j.thromres.2022.01.029
Autor:
Vijay Govindarajan, Robert Flaumenhaft, Daniel S. Hariprasad, Jaques Reifman, Arun V. Kolanjiyil, Alexander Y. Mitrophanov, Steven P. Grover, Ginu Unnikrishnan, Glenn Merrill-Skoloff
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40:2114-2126
Objective: Quantitative relationships between the extent of injury and thrombus formation in vivo are not well understood. Moreover, it has not been investigated how increased injury severity translates to blood-flow modulation. Here, we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06d05a2dd27a7673e23af9dfbbe27d6
https://doi.org/10.1161/atvbaha.120.314786
https://doi.org/10.1161/atvbaha.120.314786
Autor:
Robert Flaumenhaft, Cedric Ghevaert, Bernhard Nieswandt, Markus Bender, Glenn Merrill-Skoloff, Joseph E. Italiano
Publikováno v:
Blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669d1d4258d539d6678781d29d1030be
https://www.repository.cam.ac.uk/handle/1810/332668
https://www.repository.cam.ac.uk/handle/1810/332668
Autor:
Mattia Renato Bordoli, Glenn Merrill-Skoloff, Malcolm Whitman, Robert Flaumenhaft, James R. Dilks, Joseph E. Italiano, L. Revollo, K. De Ceunynck, Vicki Rosen, Christian G. Peters, Andreia M. Ionescu, Leila Noetzli
Tyrosine phosphorylation of proteins secreted into the extracellular space has been observed in cell cultures and in vivo, yet little is known about the role that phosphorylation of extracellular proteins serves in modulating cell function. An import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0490ae9efbf2d4f6dc0d86babf415cb
https://doi.org/10.1101/2021.01.24.427281
https://doi.org/10.1101/2021.01.24.427281
Autor:
Vijay Govindarajan, Robert Flaumenhaft, Moua Yang, Alexander Y Mitrophanov, Glenn Merrill-Skoloff, Steven P. Grover, Pavan K. Bendapudi
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 18(11)
Background The cremaster arteriole laser-induced injury model is a powerful technique with which to investigate the molecular mechanisms that drive thrombus formation. This model is capable of direct visualization and quantification of accumulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0882cd9e09b1d85f27aca9418fcb0efe
https://pubmed.ncbi.nlm.nih.gov/33463084
https://pubmed.ncbi.nlm.nih.gov/33463084
Autor:
Leila Denise Revollo, Christian G. Peters, Leila Noetzli, Malcolm Whitman, Vicki Rosen, Mattia Renato Bordoli, Karen De Ceunynck, Robert Flaumenhaft, Shihui Guo, Andreia M. Ionescu, James R. Dilks, Joseph E. Italiano, Glenn Merrill-Skoloff
Publikováno v:
Blood
Tyrosine phosphorylation of extracellular proteins is observed in cell cultures and in vivo, but little is known about the functional roles of tyrosine phosphorylation of extracellular proteins. Vertebrate lonesome kinase (VLK) is a broadly expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231276ba136b503add6167a3a719c4d5
https://pubmed.ncbi.nlm.nih.gov/34989772
https://pubmed.ncbi.nlm.nih.gov/34989772
Autor:
Sol Schulman, Emale El-Darzi, Kathelijne Peerlinck, Chad A. Cowan, Calvin R. Schuster, Marisa A Brake, Mary H.C. Florido, Robert Flaumenhaft, Ernest Turro, Max Friesen, Nihr BioResource, Kathleen Freson, Willem H. Ouwehand, Glenn Merrill-Skoloff, Bruce Furie, Randal J. Westrick, Lin Lin
Publikováno v:
J Clin Invest
Tissue factor (TF) is the primary initiator of blood coagulation in vivo and the only blood coagulation factor for which a human genetic defect has not been described. As there are no routine clinical assays that capture the contribution of endogenou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa836d3c1f116210052b3697b568d3a8
https://pubmed.ncbi.nlm.nih.gov/32663190
https://pubmed.ncbi.nlm.nih.gov/32663190