Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Glenn K. Wakley"'
Autor:
Russell T. Turner, Joseph Garand, Daniel Brown, Norman H. Bell, Glenn K. Wakley, Bernard W. Szukalski
Publikováno v:
Journal of Bone and Mineral Research. 7:11-19
Gallium nitrate lowers the serum calcium in patients with hypercalcemia caused by malignancy and is available for clinical use. The mechanism for the hypocalcemic action is unknown, however. The present studies were undertaken to determine the effect
Publikováno v:
Journal of Bone and Mineral Research. 2:449-456
To determine whether the nonsteroidal antiestrogen tamoxifen behaves as either an agonist or antagonist of estrogen on bone, the effects of ovariectomy, 17 beta-estradiol, and tamoxifen were compared on radial growth at the tibial diaphysis in young
Publikováno v:
Journal of Bone and Mineral Research. 21:1409-1416
Mechanical experiments on cadaveric thoracolumbar spine specimens showed that intervertebral disc degeneration was associated with reduced loading of the anterior vertebral body in upright postures. Reduced load bearing corresponded to locally reduce
Publikováno v:
Journal of Bone and Mineral Research. 12:464-471
Androgens stimulate bone formation and play an important role in the maintenance of bone mass. Clinical observations suggest that both gonadal and adrenal androgens contribute to the positive impact of androgenic steroids on bone metabolism. We inves
Publikováno v:
Endocrinology. 129:1568-1574
Tamoxifen is a nonsteroidal antiestrogen which has been reported by various investigators to have estrogen agonist and antagonist effects on rat bone. These different interpretations may be due to differences in the ovarian status, estrogen levels, a
Publikováno v:
Veterinary journal (London, England : 1997). 172(1)
Dorsal displacement of the soft palate is a common cause of upper airway obstruction in racehorses and is of unknown aetiology. To determine whether the palate may displace for structural reasons, knowledge of the normal soft palate is required. The
Autor:
Ulrich Schneider, Glenn K. Wakley, Florian Geiger, Irma Börcsök, Hans U. Schairer, Fritz Uwe Niethard, Reinhard Ziegler, U. Sommer, Christian Kasperk
Publikováno v:
The Journal of Experimental Medicine
The endothelial cell–derived peptide endothelin 1 (ET1) stimulates cell proliferation and differentiated functions of human osteoblastic cells (HOC), and HOC constitutively express the endothelin A receptor (ETRA). Therefore, ET1 may play an import
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 11(2)
Cell culture studies suggest that the aluminum silicate polymer sodium Zeolite A (SZA) increases bone cell proliferation and extracellular matrix production. This study in rats investigated the short-term (2 weeks) and long-term (18 weeks) in vivo ef
Publikováno v:
Endocrinology. 133(6)
The purpose of these experiments was to test the hypothesis that estrogen has an anabolic effect on cancellous bone formation in long bones of growing rats. In the present studies, estrogen decreased measurements related to cancellous bone formation,
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 6(4)
This report describes histomorphometric evidence for an important role of androgens in maintaining cancellous bone balance at a remodeling site in vivo. Rats were orchiectomized (ORX) at 7 weeks of age and received either androgens or vehicle 1 week