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Akademický článek

The presence of CpGs in AAV gene therapy vectors induces a plasmacytoid dendritic cell-like population very early after administration.

Autor: Glenn JD; REGENXBIO Inc., 9804 Medical Center Drive, Rockville, MD 20850, USA. Electronic address: jglenn@regenxbio.com., Negash H; REGENXBIO Inc., 9804 Medical Center Drive, Rockville, MD 20850, USA., Henry W; REGENXBIO Inc., 9804 Medical Center Drive, Rockville, MD 20850, USA., Qian R; REGENXBIO Inc., 9804 Medical Center Drive, Rockville, MD 20850, USA., Liu Y; REGENXBIO Inc., 9804 Medical Center Drive, Rockville, MD 20850, USA., Danos O; REGENXBIO Inc., 9804 Medical Center Drive, Rockville, MD 20850, USA., Bruder JT; REGENXBIO Inc., 9804 Medical Center Drive, Rockville, MD 20850, USA., Karumuthil-Melethil S; REGENXBIO Inc., 9804 Medical Center Drive, Rockville, MD 20850, USA.

Publikováno v: Cellular immunology [Cell Immunol] 2024 May-Jun; Vol. 399-400, pp. 104823. Date of Electronic Publication: 2024 Mar 19.

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Akademický článek

Characterization and biodistribution of under-employed gene therapy vector AAV7.

Autor: Yost SA; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Firlar E; Institute of Quantitative Biomedicine and Rutgers CryoEM & Nanoimaging Facility, Rutgers, The State University of New Jersey , Piscataway, New Jersey, USA., Glenn JD; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Carroll HB; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Foltz S; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Giles AR; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Egley JM; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Firnberg E; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Cho S; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Nguyen T; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Henry WM; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Janczura KJ; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Bruder J; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Liu Y; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Danos O; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Karumuthil-Melethil S; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Pannem S; Invicro LLC , Needham, Massachusetts, USA., Yost V; Invicro LLC , Needham, Massachusetts, USA., Engelson Y; Invicro LLC , Needham, Massachusetts, USA., Kaelber JT; Institute of Quantitative Biomedicine and Rutgers CryoEM & Nanoimaging Facility, Rutgers, The State University of New Jersey , Piscataway, New Jersey, USA., Dimant H; Invicro LLC , Needham, Massachusetts, USA.; Emit Imaging , Baltimore, Maryland, USA., Smith JB; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA., Mercer AC; Research and Early Development, REGENXBIO Inc. , Rockville, Maryland, USA.

Publikováno v: Journal of virology [J Virol] 2023 Nov 30; Vol. 97 (11), pp. e0116323. Date of Electronic Publication: 2023 Oct 16.

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Akademický článek

MYMD-1, a novel alkaloid compound, ameliorates the course of experimental autoimmune encephalomyelitis.

Autor: Glenn JD; Depts of Neurology, Johns Hopkins University School of Medicine, USA., Pantoja IM; Depts of Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, USA., Caturegli P; Depts of Pathology, Johns Hopkins University School of Medicine, USA., Whartenby KA; Depts of Neurology, Johns Hopkins University School of Medicine, USA; Depts of Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, USA; Depts of Oncology, Johns Hopkins University School of Medicine, USA. Electronic address: whartenby@jhmi.edu.

Publikováno v: Journal of neuroimmunology [J Neuroimmunol] 2020 Feb 15; Vol. 339, pp. 577115. Date of Electronic Publication: 2019 Nov 20.

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Akademický článek

Frontline Science: Induction of experimental autoimmune encephalomyelitis mobilizes Th17-promoting myeloid derived suppressor cells to the lung.

Autor: Glenn JD; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Liu C; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Whartenby KA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Publikováno v: Journal of leukocyte biology [J Leukoc Biol] 2019 May; Vol. 105 (5), pp. 829-841. Date of Electronic Publication: 2019 Feb 14.

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Akademický článek

Gemcitabine directly inhibits effector CD4 T cell activation and prevents experimental autoimmune encephalomyelitis.

Autor: Glenn JD; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA. Electronic address: jglenn7@jhmi.edu., Xue P; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA. Electronic address: pxue2@jhu.edu., Whartenby KA; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA. Electronic address: whartenby@jhmi.edu.

Publikováno v: Journal of neuroimmunology [J Neuroimmunol] 2018 Mar 15; Vol. 316, pp. 7-16. Date of Electronic Publication: 2017 Dec 08.

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Akademický článek

The Dynamics of the Gut Microbiome in Multiple Sclerosis in Relation to Disease.

Autor: Mowry EM; Department of Neurology, Johns Hopkins School of Medicine, 600 North Wolfe Street, Pathology 627, Baltimore, MD 21287, USA., Glenn JD; Department of Neurology, Johns Hopkins School of Medicine, 600 North Wolfe Street, Meyer Building, Room 6-138, Baltimore, MD 21287, USA. Electronic address: jglenn7@jhmi.edu.

Publikováno v: Neurologic clinics [Neurol Clin] 2018 Feb; Vol. 36 (1), pp. 185-196.

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Akademický článek

CNS-targeted autoimmunity leads to increased influenza mortality in mice.

Autor: Glenn JD; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205., Smith MD; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205., Xue P; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205., Chan-Li Y; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205., Collins S; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205., Calabresi PA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205., Horton MR; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205., Whartenby KA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205 whartenby@jhmi.edu.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

Publikováno v: The Journal of experimental medicine [J Exp Med] 2017 Feb; Vol. 214 (2), pp. 297-307. Date of Electronic Publication: 2017 Jan 05.

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Akademický článek

Emerging Concepts on the Gut Microbiome and Multiple Sclerosis.

Autor: Glenn JD; Division of Neuroimmunology and Neurological Infections, Department of Neurology, Johns Hopkins University , School of Medicine, Baltimore, Maryland., Mowry EM; Division of Neuroimmunology and Neurological Infections, Department of Neurology, Johns Hopkins University , School of Medicine, Baltimore, Maryland.

Publikováno v: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research [J Interferon Cytokine Res] 2016 Jun; Vol. 36 (6), pp. 347-57. Date of Electronic Publication: 2016 May 04.

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