Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Glenn F. W. Walpole"'
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Kinetics of cargo degradation in phagosomes are measured through engineered RotSensors, capturing their translational and rotational dynamics in parallel.
Externí odkaz:
https://doaj.org/article/6f016b712fab48a0a0293824c3971bff
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The dynamic re-organization of cellular membranes in response to extracellular stimuli is fundamental to the cell physiology of myeloid and lymphoid cells of the immune system. In addition to maintaining cellular homeostatic functions, remodeling of
Externí odkaz:
https://doaj.org/article/eb5816d9f36a435db0d7c559b582933d
Autor:
Glenn F. W. Walpole, Jonathan Pacheco, Neha Chauhan, Jonathan Clark, Karen E. Anderson, Yazan M. Abbas, Danielle Brabant-Kirwan, Fernando Montaño-Rendón, Zetao Liu, Hongxian Zhu, John H. Brumell, Alexander Deiters, Len R. Stephens, Phillip T. Hawkins, Gerald R. V. Hammond, Sergio Grinstein, Gregory D. Fairn
Publikováno v:
Nature Cell Biology. 24:708-722
Despite their low abundance, phosphoinositides play a central role in membrane traffic and signalling. PtdIns(3,4,5)P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d77aec7fe2c7ac16d3ceec8f51a2663
https://doi.org/10.1038/s41556-022-00895-y
https://doi.org/10.1038/s41556-022-00895-y
Autor:
Fernando Montaño-Rendón, Glenn F. W. Walpole, Matthias Krause, Gerald R.V. Hammond, Sergio Grinstein, Gregory D. Fairn
Phosphoinositides are pivotal regulators of vesicular traffic and signaling during phagocytosis. Phagosome formation, the initial step of the process, is characterized by local membrane remodelling and reorganization of the actin cytoskeleton that le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84b86ffc8dd261a07582c277bb49f1d1
https://doi.org/10.1101/2022.03.08.483476
https://doi.org/10.1101/2022.03.08.483476
Publikováno v:
Microbial Cell, Vol 7, Iss 12, Pp 323-325 (2020)
Microbial Cell
Microbial Cell
Professional phagocytes represent a critical node in innate immunity and tissue homeostasis through their specialized ability to eat, drink, and digest material from the extracellular milieu. The degradative and microbicidal functions of phagocytes r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9dd7156f9e471a2286f36c0417bdd33
http://microbialcell.com/researcharticles/2020a-yang-microbial-cell/
http://microbialcell.com/researcharticles/2020a-yang-microbial-cell/
Autor:
Hongxian Zhu, Yazan M. Abbas, Alexander Deiters, Neha Chauhan, Zetao Liu, Jonathan Pacheco, Gerald R.V. Hammond, Glenn F. W. Walpole, Sergio Grinstein, Gregory D. Fairn, Fernando Montaño-Rendón, John H. Brumell
Despite their comparatively low abundance, phosphoinositides play a central role in membrane traffic and signalling. PtdIns(3,4,5)P3 and PtdIns(3,4)P2 are uniquely important, as they promote cell growth, survival, and migration. Pathogenic organisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aa850c18561cb2402e780f76641eea1
https://doi.org/10.21203/rs.3.rs-576813/v1
https://doi.org/10.21203/rs.3.rs-576813/v1
Autor:
Glenn F. W. Walpole, Jonathan Pacheco, Neha Chauhan, Yazan M. Abbas, Fernando Montaño-Rendón, Zetao Liu, Hongxian Zhu, John H. Brumell, Alexander Deiters, Gerald R.V. Hammond, Sergio Grinstein, Gregory D. Fairn
Despite their comparatively low abundance, phosphoinositides play a central role in membrane traffic and signalling. PtdIns(3,4,5)P3 and PtdIns(3,4)P2 are uniquely important, as they promote cell growth, survival, and migration. Pathogenic organisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec36a92205b86e72f1b063b0f6a80249
https://doi.org/10.1101/2021.05.25.445663
https://doi.org/10.1101/2021.05.25.445663
Immune cells degrade internalized pathogens in phagosomes through sequential biochemical changes. The degradation must be fast enough for effective infection control. The presumption is that each phagosome degrades cargos autonomously with a distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bac526fe27fbf5e53bc747fc3006b8c
https://doi.org/10.1101/2021.04.04.438376
https://doi.org/10.1101/2021.04.04.438376
Autor:
Michael M. Kozlov, Jonathan Plumb, Ehud Haimov, Glenn F. W. Walpole, Sharon Eisenberg, Sergio Grinstein
Publikováno v:
Molecular Biology of the Cell
Anionic phospholipids can confer a net negative charge on biological membranes. This surface charge generates an electric field that serves to recruit extrinsic cationic proteins, can alter the disposition of transmembrane proteins and causes the loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168eeebc37ab320db23f9a1032b1fa2f
https://pubmed.ncbi.nlm.nih.gov/33263429
https://pubmed.ncbi.nlm.nih.gov/33263429