Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Glenn E. Morris"'
Autor:
Ian Holt, Heidi R. Fuller, Roland F. R. Schindler, Sally L. Shirran, Thomas Brand, Glenn E. Morris
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background Popeye domain-containing proteins 1 and 2 (POPDC1 and POPDC2) are transmembrane proteins involved in cyclic AMP-mediated signalling processes and are required for normal cardiac pacemaking and conduction. In order to identify nove
Externí odkaz:
https://doaj.org/article/f0b185ac5ee94678b3dd39c6546bae6d
Autor:
Le Thanh Lam, Sally L. Shirran, Ian Holt, Heidi R. Fuller, Qiuping Zhang, Glenn E. Morris, Caroline Sewry, Catherine M. Shanahan
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
This project was supported by grants from the British Heart Foundation (PG/11/71/29091 and PG/16/68/31991) and the Orthopaedic Institute Ltd., (RJAH Orthopaedic Hospital, Oswestry, UK). Nesprins, nuclear envelope spectrin-repeat proteins encoded by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700aace8ad766270eb0f2dfd3dbc91b6
http://link.springer.com/article/10.1038/s41598-019-50728-6
http://link.springer.com/article/10.1038/s41598-019-50728-6
Autor:
Marisol Montolio, Nicole A. Datson, Francesco Muntoni, Eric P. Hoffman, Judith C.T. van Deutekom, Pallavi Lonkar, Michael Binks, Jane Owens, Virginia Arechavala-Gomeza, Glenn E. Morris, V. Ashutosh Rao, Rahul Phadke, Hendrik Neubert, Annemieke Aartsma-Rus, Jennifer E. Morgan
Publikováno v:
Journal of Neuromuscular Diseases
Representatives of academia, patient organisations, industry and the United States Food and Drug Administration attended a workshop on dystrophin quantification methodology. The aims of the workshop were to provide an overview of methods used to quan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e506f80eb792e66b1ba66e81e1c57c
http://europepmc.org/articles/PMC6398559
http://europepmc.org/articles/PMC6398559
Autor:
Nguyen Thuy Duong, Glenn E Morris, Le Thanh Lam, Qiuping Zhang, Caroline A Sewry, Catherine M Shanahan, Ian Holt
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94380 (2014)
Nesprin-1-giant and nesprin-2-giant regulate nuclear positioning by the interaction of their C-terminal KASH domains with nuclear membrane SUN proteins and their N-terminal calponin-homology domains with cytoskeletal actin. A number of short isoforms
Externí odkaz:
https://doaj.org/article/4188f96e21ba474ab3f7d345d8a475bc
Autor:
Ian Holt, Mubashir Hanif, Katarina Pelin, Carina Wallgren-Pettersson, Caroline Sewry, Glenn E. Morris, J. Laitila, Le Thanh Lam
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Nebulin is a very large protein required for assembly of the contractile machinery in muscle. Mutations in the nebulin gene NEB are a common cause of nemaline myopathy. Nebulin mRNA is alternatively-spliced so that each mRNA contains either exon 143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c06793e6388770b1260febcbb8437815
http://link.springer.com/article/10.1038/s41598-018-33281-6
http://link.springer.com/article/10.1038/s41598-018-33281-6
Publikováno v:
Neuromuscular disorders : NMD. 30(6)
Emery-Dreifuss muscular dystrophy (EDMD) is a rare genetic disorder characterised by the early development of muscle contractures, progressive muscle weakness, and heart abnormalities. The latter may result in serious complications, or in severe case
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c7c76944ed4b32ab50f0acd612a283
https://pubmed.ncbi.nlm.nih.gov/32522500
https://pubmed.ncbi.nlm.nih.gov/32522500
Autor:
Glenn E. Morris, Le Thanh Lam, Caroline Sewry, J. Laitila, Carina Wallgren-Pettersson, C. Pelin, Ian Holt
Publikováno v:
Neuromuscular Disorders. 29:S96
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73bf2c5b97fadf0bb7c160e3d26f2cfc
https://doi.org/10.1016/j.nmd.2019.06.219
https://doi.org/10.1016/j.nmd.2019.06.219
Autor:
Ian, Holt, Nguyen Thuy, Duong, Qiuping, Zhang, Le Thanh, Lam, Caroline A, Sewry, Kamel, Mamchaoui, Catherine M, Shanahan, Glenn E, Morris
Publikováno v:
BMC Cell Biology
Background Nesprin-1-giant (1008kD) is a protein of the outer nuclear membrane that links nuclei to the actin cytoskeleton via amino-terminal calponin homology domains. The short nesprin-1 isoform, nesprin-1-α2, is present only in skeletal and cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a557a45072804ca10355366abe1433a8
https://pubmed.ncbi.nlm.nih.gov/27350129
https://pubmed.ncbi.nlm.nih.gov/27350129
Autor:
Heidi R Fuller, Berhan eMandefro, Sally L Shirran, Andrew R Gross, Anjoscha Samija Kaus, Catherine H Botting, Glenn E Morris, Dhruv eSareen
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2016)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
This work was supported by The RJAH Institute of Orthopaedics, UK (H.F.), The SMA Trust, UK (H.F.), Cedars-Sinai Institutional startup funds (D.S), California Institute for Regenerative Medicine Grant RT-02040 (D.S.), National Center for Advancing Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68b9f26cbbf4bc72c3362f4dc338cb1
https://hdl.handle.net/10023/8083
https://hdl.handle.net/10023/8083
Autor:
Tatsushi Toda, Le Thanh Lam, Nguyen thi Man, Kazuhiro Kobayashi, Glenn E. Morris, Tracy A. Lynch
Publikováno v:
Biochemical and Biophysical Research Communications. 424:354-357
Mutations in the gene encoding fukutin protein cause Fukuyama muscular dystrophy, a severe congenital disorder that occurs mainly in Japan. A major consequence of the mutation is reduced glycosylation of alpha-dystroglycan, which is also a feature of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e5a4ddbe04eea121509eb8b36ce5c2
https://doi.org/10.1016/j.bbrc.2012.06.147
https://doi.org/10.1016/j.bbrc.2012.06.147