Zobrazeno 1 - 10
of 448
pro vyhledávání: '"Glenn E M, Maguire"'
Autor:
Lloyd C. Chetty, Hendrik G. Kruger, Per I. Arvidsson, Glenn E. M. Maguire, Thavendran Govender, Tricia Naicker
Publikováno v:
ACS Omega, Vol 9, Iss 35, Pp 37155-37162 (2024)
Externí odkaz:
https://doaj.org/article/1363742c463e4e0fa08afe095e98fede
Autor:
Friday E. Ani, Collins U. Ibeji, Nnamdi L. Obasi, Monsuru T. Kelani, Kingsley Ukogu, Gideon F. Tolufashe, Segun A. Ogundare, Oluwatoba E. Oyeneyin, Glenn E. M. Maguire, Hendrik G. Kruger
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Two Schiff bases, (E)-1-(4-methoxyphenyl)-N-((E)-3-(4-nitrophenyl)allylidene)methanamine (compound 1) and (E)-N-((E)-3-(4-nitrophenyl)allylidene)-2-phenylethanamine (compound 2) have been synthesized and characterized using spectroscopic met
Externí odkaz:
https://doaj.org/article/49d7c559f51648bd991c477bb6e0ef8a
Autor:
Nakita Reddy, Letisha Girdhari, Mbongeni Shungube, Arnoldus C. Gouws, Byron K. Peters, Kamal K. Rajbongshi, Sooraj Baijnath, Sipho Mdanda, Thandokuhle Ntombela, Thilona Arumugam, Linda A. Bester, Sanil D. Singh, Anil Chuturgoon, Per I. Arvidsson, Glenn E. M Maguire, Hendrik G. Kruger, Thavendran Govender, Tricia Naicker
Publikováno v:
Antibiotics, Vol 12, Iss 4, p 633 (2023)
Virulent Enterobacterale strains expressing serine and metallo-β-lactamases (MBL) genes have emerged responsible for conferring resistance to hard-to-treat infectious diseases. One strategy that exists is to develop β-lactamase inhibitors to counte
Externí odkaz:
https://doaj.org/article/72015b20994f46ae9bddd7b2baa61e04
Autor:
Byron K. Peters, Nakita Reddy, Mbongeni Shungube, Letisha Girdhari, Sooraj Baijnath, Sipho Mdanda, Lloyd Chetty, Thandokuhle Ntombela, Thilona Arumugam, Linda A. Bester, Sanil D. Singh, Anil Chuturgoon, Per I. Arvidsson, Glenn E. M. Maguire, Hendrik G. Kruger, Tricia Naicker, Thavendran Govender
Publikováno v:
ACS Infectious Diseases. 9:486-496
Autor:
Sibusiso B. Maseko, Gyanu Lamichhane, Bahareh Honarparvar, Tricia Naicker, Thavendran Govender, Thandokuhle Ntombela, Glenn E. M. Maguire, Anya Seupersad, Collins U. Ibeji, Gideon F. Tolufashe, Sooraj Baijnath, Hendrik G. Kruger, Siyabonga I. Maphumulo
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:7645-7655
Mycobacterium tuberculosis cell wall is intricate and impermeable to many agents. A D, D-carboxypeptidase (DacB1) is one of the enzymes involved in the biosynthesis of cell wall peptidoglycan and catalyzes the terminal D-alanine cleavage from pentape
Microwave-assisted synthesis of meso-carboxyalkyl-BODIPYs and an application to fluorescence imaging
Autor:
Glenn E. M. Maguire, Hendrick G. Kruger, Neliswa Z Mhlongo, Thavendran Govender, Tricia Naicker, Thomas Ebenhan, Cathryn H.S. Driver
Publikováno v:
Organic & Biomolecular Chemistry. 18:7876-7883
In this study, a significantly improved method for the synthesis of modular meso-BODIPY (boron dipyrromethene) derivatives possessing a free carboxylic acid group (which was subsequently coupled to peptides), is disclosed. This method provides a vast
Publikováno v:
Viruses, Vol 4, Iss 4, Pp 488-520 (2012)
Suboptimal adherence, toxicity, drug resistance and viral reservoirs make the lifelong treatment of HIV infection challenging. The emerging field of nanotechnology may play an important role in addressing these challenges by creating drugs that posse
Externí odkaz:
https://doaj.org/article/dfdf764f884f4cd69823ba5c13b54853
Publikováno v:
Molecules, Vol 23, Iss 7, p 1676 (2018)
In the last 30 years, C–C cross coupling reactions have become a reliable technique in organic synthesis due their versatility and efficiency. While drawbacks have been experienced on an industrial scale with the use of homogenous systems, many att
Externí odkaz:
https://doaj.org/article/38c5cd987a5b43579cc7e208fd2b483d
Autor:
Zainab K. Sanusi, Thavendran Govender, Monsurat M. Lawal, Hendrik G. Kruger, Glenn E. M. Maguire, Bahareh Honarparvar
Publikováno v:
The Journal of Physical Chemistry B. 123:6389-6400
The Human Immunodeficiency Virus type 1 (HIV-1) protease is a crucial target for HIV/AIDS treatment, and understanding its catalytic mechanism is the basis on which HIV-1 enzyme inhibitors are developed. Several experimental studies have indicated th
Autor:
Monsurat M. Lawal, Gyanu Lamichhane, Thavendran Govender, Hendrik G. Kruger, Glenn E. M. Maguire, Gideon F. Tolufashe, Collins U. Ibeji, Bahareh Honarparvar, Tricia Naicker
Publikováno v:
ChemPhysChem. 20:1126-1134
β-lactam antibiotics, which are used to treat infectious diseases, are currently the most widely used class of antibiotics. This study focused on the chemical reactivity of five- and six-membered ring systems attached to the β-lactam ring. The ring