Precision Medicine in Assisted Conception: A Multicenter Observational Treatment Cohort Study of the Annexin A5 M2 Haplotype as a Biomarker for Antithrombotic Treatment to Improve Pregnancy Outcome

Autor: Simon Fishel, Deborah Baker, Janine Elson, Maha Ragunath, Glenn Atkinson, Adel Shaker, Ahmed Omar, Rahnuma Kazem, Ashley Beccles, Ian A. Greer

Publikováno v: EBioMedicine, Vol 10, Iss C, Pp 298-304 (2016)

Background: Pregnancy failure and placenta mediated pregnancy complications affect >25% of pregnancies. Although there is biological plausibility for a procoagulant mechanism underlying some of these events, antithrombotic intervention trials demonst

Externí odkaz: https://doaj.org/article/fcad05fe306f49a4a0aba147e51e3765

Precision Medicine in Assisted Conception: A Multicenter Observational Treatment Cohort Study of the Annexin A5 M2 Haplotype as a Biomarker for Antithrombotic Treatment to Improve Pregnancy Outcome

Autor: Ashley Beccles, Simon Fishel, Adel Shaker, Rahnuma Kazem, Glenn Atkinson, Deborah Baker, Ian A. Greer, Maha Ragunath, Janine Elson, Ahmed Omar

Publikováno v: Fishel, S, Baker, D, Elson, J, Ragunath, M, Atkinson, G, Shaker, A, Omar, A, Kazem, R, Beccles, A & Greer, I 2016, ' Precision Medicine in Assisted Conception: A Multicenter Observational Treatment Cohort Study of the Annexin A5 M2 Haplotype as a Biomarker for Antithrombotic Treatment to Improve Pregnancy Outcome ', EBioMedicine, vol. 10, pp. 298-304 . https://doi.org/10.1016/j.ebiom.2016.06.024
EBioMedicine
EBioMedicine, Vol 10, Iss C, Pp 298-304 (2016)

Background Pregnancy failure and placenta mediated pregnancy complications affect > 25% of pregnancies. Although there is biological plausibility for a procoagulant mechanism underlying some of these events, antithrombotic intervention trials demonst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56c43378f517e6dd8503482e5d7e9cd
https://pure.qub.ac.uk/en/publications/precision-medicine-in-assisted-conception-a-multicenter-observational-treatment-cohort-study-of-the-annexin-a5-m2-haplotype-as-a-biomarker-for-antithrombotic-treatment-to-improve-pregnancy-outcome(80b33265-4362-4374-b7b1-8d7bad505f3b).html

Diagnostic techniques: Rapid genetic diagnosis at 7-9 weeks gestation: diagnosis of sex, single gene defects and DNA fingerprint from coelomic samples

Autor: Ian Findlay, Anthony J. Rutherford, Glenn Atkinson, Michaela Chambers, Philip Quirke, James Campbell

Publikováno v: Human Reproduction. 11:2548-2553

Prenatal diagnosis (chorionic villus sampling (CVS) or amniocentesis) is performed at a relatively late stage of pregnancy (11-18 weeks). Such tests have significant disadvantages including increased risk of miscarriage and delay before results are k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::275150aa3fb82db5c67b945d28417f8a
https://doi.org/10.1093/oxfordjournals.humrep.a019158

Clinical experience with preimplantation diagnosis of sex by dual fluorescent in situ hybridization

Autor: Darren K. Griffin, Alan H. Handyside, Joyce C. Harper, Leeanda J. Wilton, Glenn Atkinson, Iakovos Soussis, Dagan Wells, Elena Kontogianni, Juan Tarin, Selmo Geber, Asangla Ao, Robert M. L. Winston, Joy D. A. Delhanty

Publikováno v: Journal of Assisted Reproduction and Genetics. 11:132-143

Our purpose was to assess the clinical application of dual fluorescent in situhybridization (FISH) for the diagnosis of sex in the human preimplantation embryo. Over a 2-year period, 18 couples at risk of transmitting X-linked recessive disorders und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe30d1effce164eb63bf9f0447c69549
https://doi.org/10.1007/bf02332090

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.