Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Glenn A. Powers"'
Autor:
Sandra Wymann, Marcel Mischnik, David Leong, Subhajit Ghosh, Xiahui Tan, Helen Cao, Benjamin Kuehnemuth, Glenn A. Powers, Partho Halder, Mitchell J. de Souza, Hannah S. James, Vesna Tomasetig, Holger Lind, Paolo Rossato, Catherine M. Owczarek, Saw Yen Ow, Steven K. Dower, Adriana Baz Morelli, Tony Rowe, Matthew P. Hardy
Publikováno v:
The Biochemical journal. 479(9)
Human Complement Receptor 1 (HuCR1) is a potent membrane-bound regulator of complement both in vitro and in vivo, acting via interaction with its ligands C3b and C4b. Soluble versions of HuCR1 have been described such as TP10, the recombinant full-le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df480786f0e2f3b18b1a8110b0b2493d
https://pubmed.ncbi.nlm.nih.gov/35470373
https://pubmed.ncbi.nlm.nih.gov/35470373
Autor:
Ruth M Kennan, Wilson Wong, Om P Dhungyel, Xiaoyan Han, David Wong, Dane Parker, Carlos J Rosado, Ruby H P Law, Sheena McGowan, Shane B Reeve, Vita Levina, Glenn A Powers, Robert N Pike, Stephen P Bottomley, A Ian Smith, Ian Marsh, Richard J Whittington, James C Whisstock, Corrine J Porter, Julian I Rood
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001210 (2010)
Many bacterial pathogens produce extracellular proteases that degrade the extracellular matrix of the host and therefore are involved in disease pathogenesis. Dichelobacter nodosus is the causative agent of ovine footrot, a highly contagious disease
Externí odkaz:
https://doaj.org/article/468ef5017baf44698c215e055cd8aa6f
Autor:
Mitchell J. de Souza, Matthew P. Hardy, Martin J. Pearse, Kim G. Lieu, Saw Yen Ow, Martin O. Spycher, Anup G. Nair, Michael J. Wilson, Jason Simmonds, Yun Dai, Sandra Wymann, Adrian Zuercher, Anna Schnell, Con Panousis, Rebecca E. Butcher, Glenn A. Powers, Marcel Mischnik, Tony Rowe, Genevieve Martin-Roussety, Adriana Baz Morelli, Helen Cao, David Leong, Shirley Taylor
Publikováno v:
The Journal of Biological Chemistry
Human complement receptor 1 (HuCR1) is a pivotal regulator of complement activity, acting on all three complement pathways as a membrane-bound receptor of C3b/C4b, C3/C5 convertase decay accelerator, and cofactor for factor I-mediated cleavage of C3b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605c43f8a6fc70ffcd57fb8866f643b1
https://doi.org/10.1074/jbc.ra120.016127
https://doi.org/10.1074/jbc.ra120.016127
Autor:
Susanne C. Feil, Guido Hansen, Glenn A. Powers, Michael W. Parker, Mary Catherine Pearce, Stephen P. Bottomley
Publikováno v:
Journal of Molecular Biology. 403:459-467
The native serpin state is kinetically trapped. However, under mildly destabilizing conditions, the conformational landscape changes, and a number of nonnative conformations with increased stability can be readily formed. The ability to undergo struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4306d652810e86f5a9e9408dfcb6f6e
https://doi.org/10.1016/j.jmb.2010.09.007
https://doi.org/10.1016/j.jmb.2010.09.007
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 907
Multimeric antibody fragments, particularly dimers (diabodies), trimers (triabodies), and tetramers (tetrabodies) of single-chain Fv molecules (scFv), provide high avidity through multivalent binding to the target antigen. The combination of their sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8e0d73f509c43b83f18158423415e40
https://pubmed.ncbi.nlm.nih.gov/22907381
https://pubmed.ncbi.nlm.nih.gov/22907381
Publikováno v:
Antibody Engineering ISBN: 9781617799730
Multimeric antibody fragments, particularly dimers (diabodies), trimers (triabodies), and tetramers (tetrabodies) of single-chain Fv molecules (scFv), provide high avidity through multivalent binding to the target antigen. The combination of their sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c17b391fe18ed2df1416f81d471ef9db
https://doi.org/10.1007/978-1-61779-974-7_39
https://doi.org/10.1007/978-1-61779-974-7_39
Autor:
Milton Thomas William Hearn, Khosse Mitri, Simon John Harris, Kirk-Ski Troung, Gabriel Widakowich, Glenn A. Powers, Chunfang Zhang
Publikováno v:
Biotechnology progress. 27(4)
Immobilized metal ion affinity chromatography (IMAC) using peptide affinity tags has become a popular tool for protein purification. An important feature dictating the use of a specific affinity tag is whether its structure influences the properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837487736d56758ff1f54f9b1c62fd00
https://pubmed.ncbi.nlm.nih.gov/21648101
https://pubmed.ncbi.nlm.nih.gov/21648101
Autor:
I. Marsh, Om P. Dhungyel, Shane Reeve, Wilson Wong, Stephen P. Bottomley, Vita Levina, Richard Whittington, Glenn A. Powers, Corrine Joy Porter, Xiaoyan Han, Robert N. Pike, David M. Wong, Carlos J. Rosado, Julian I. Rood, Ruth M. Kennan, James C. Whisstock, A. Ian Smith, Sheena McGowan, Ruby H. P. Law, Dane Parker
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 6, Iss 11, p e1001210 (2010)
PLoS Pathogens, Vol 6, Iss 11, p e1001210 (2010)
Many bacterial pathogens produce extracellular proteases that degrade the extracellular matrix of the host and therefore are involved in disease pathogenesis. Dichelobacter nodosus is the causative agent of ovine footrot, a highly contagious disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585a6364eac4553dab638273b6e00436
https://pubmed.ncbi.nlm.nih.gov/21124876
https://pubmed.ncbi.nlm.nih.gov/21124876
Autor:
Stephen P. Bottomley, Glenn A. Powers, Geoffrey J. Howlett, Chi L.L. Pham, Mary Catherine Pearce
Publikováno v:
Journal of molecular biology. 366(2)
Protein aggregation underlies an increasing number of human diseases. Recent experiments have shown that the aggregation reaction is exquisitely specific involving particular interactions between non-native proteins. However, aggregation of certain p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41fb7f2041807f4b9c03be3ec9987aa
https://pubmed.ncbi.nlm.nih.gov/17174330
https://pubmed.ncbi.nlm.nih.gov/17174330
Autor:
John M. Paden, Glenn F. Powers
Publikováno v:
Science Education. 42:253-255
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78f167e736372a1765c1be7140c7ce84
https://doi.org/10.1002/sce.3730420310
https://doi.org/10.1002/sce.3730420310