Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Glenn, Pauwelyn"'
Autor:
Charlotte Beerts, Sarah Y. Broeckx, Eva Depuydt, Liesa Tack, Lore Van Hecke, Koen Chiers, Leen Van Brantegem, Gabriele Braun, Klaus Hellmann, Nathalie de Bouvre, Nathalie Van Bruaene, Tine De Ryck, Luc Duchateau, Bernadette Van Ryssen, Kathelijne Peremans, Jimmy H. Saunders, Geert Verhoeven, Glenn Pauwelyn, Jan H. Spaas
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-18 (2023)
Abstract Background As current therapies for canine osteoarthritis (OA) provide mainly symptomatic improvement and fail to address the complex pathology of the disease, mesenchymal stem cells (MSCs) offer a promising biological approach to address bo
Externí odkaz:
https://doaj.org/article/e56fcc19e4474e76ac94d69bf4a9985c
Autor:
Jonas Steenbrugge, Glenn Pauwelyn, Kristel Demeyere, Nausikaa Devriendt, Hilde de Rooster, Niek N. Sanders, Jan H. Spaas, Evelyne Meyer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Triple-negative breast cancer (TNBC) remains difficult to treat, especially due to ineffective immune responses. Current treatments mainly aim at a cytotoxic effect, whereas (stem) cell therapies are being investigated for their immune stimulatory ca
Externí odkaz:
https://doaj.org/article/150f70b8bbd7473a93977f298650025d
Autor:
Charlotte Beerts, Glenn Pauwelyn, Eva Depuydt, Yangfeng Xu, Jimmy H. Saunders, Kathelijne Peremans, Jan H. Spaas
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Osteoarthritis (OA) is a highly prevalent condition in dogs, causing a substantial reduction in quality of life and welfare of the animals. Current disease management focusses on pain relief but does not stop the progression of the disease. Therefore
Externí odkaz:
https://doaj.org/article/3978519a33404fde93223e481657c6d5
Autor:
Charlotte Beerts, Carlien Brondeel, Glenn Pauwelyn, Eva Depuydt, Liesa Tack, Luc Duchateau, Yangfeng Xu, Jimmy H. Saunders, Kathelijne Peremans, Jan H. Spaas
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2021)
Abstract Background Mesenchymal stem cell treatments in dogs have been investigated as a potential innovative alternative to current conventional therapies for a variety of conditions. So far, the precise mode of action of the MSCs has yet to be dete
Externí odkaz:
https://doaj.org/article/f6ef7d77df224e1a8cb4e5575acbef51
Autor:
Glenn Pauwelyn, Lise Vlerick, Robrecht Dockx, Jeroen Verhoeven, Andre Dobbeleir, Tim Bosmans, Kathelijne Peremans, Christian Vanhove, Ingeborgh Polis, Filip De Vos
Publikováno v:
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-11 (2019)
Abstract Background Currently, [18F] altanserin is the most frequently used PET-radioligand for serotonin2A (5-HT2A) receptor imaging in the human brain but has never been validated in dogs. In vivo imaging of this receptor in the canine brain could
Externí odkaz:
https://doaj.org/article/6b3ee56da56f4b00980243c550bbd958
Autor:
Carlien Brondeel, Glenn Pauwelyn, Evelien de Bakker, Jimmy Saunders, Yves Samoy, Jan H. Spaas
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Osteoarthritis (OA) is currently an incurable and progressive condition in dogs causing chronic joint pain and possibly increasing disability. Due to the poor healing capacity of cartilage lesions that occur with OA, development of effective therapeu
Externí odkaz:
https://doaj.org/article/b5e8e77bcaf74e5c96ccecd95ac0ea3b
Autor:
Glenn Pauwelyn, Lise Vlerick, Robrecht Dockx, Jeroen Verhoeven, Andre Dobbeleir, Kathelijne Peremans, Ingeborg Goethals, Tim Bosmans, Christian Vanhove, Filip De Vos, Ingeborgh Polis
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218237 (2019)
Numerous studies have shown that the serotonin1A (5-HT1A) receptor is implicated in the pathophysiology and treatment of several psychiatric and neurological disorders. Furthermore, functional imaging studies in a variety of species have demonstrated
Externí odkaz:
https://doaj.org/article/e7d4e26465c7459a93a282ec8749534b
Autor:
Carlien Brondeel, Frederik Weekers, Lore van Hecke, Eva Depuydt, Glenn Pauwelyn, Geert Verhoeven, Nathalie de Bouvré, Peter De Roeck, Peter Vandekerckhove, Pieter Vanacker, Davina Böhm-Geerdink, Robert Daems, Luc Duchateau, Jimmy Saunders, Yves Samoy, Jan H. Spaas
Publikováno v:
Stem Cells and Development.
Autor:
Christian Vanhove, Filip De Vos, Robrecht Raedt, Ingeborg Goethals, Glenn Pauwelyn, Charlotte Bouckaert, Jeroen Verhoeven, Sarah Piron, Tristan Baguet, Benedicte Descamps
Publikováno v:
Nuclear Medicine and Biology. :9-16
Introduction Considering the need for rapid change of treatment in recurrent glioblastoma (GB), it is of utmost importance to characterize PET radiopharmaceuticals that allow early discrimination of tumor from therapy-related effects. In this study,
Autor:
Luc Duchateau, Yangfeng Xu, Liesa Tack, Jan H. Spaas, Kathelijne Peremans, Charlotte Beerts, Glenn Pauwelyn, Jimmy Saunders, Eva Depuydt, Carlien Brondeel
Publikováno v:
STEM CELL RESEARCH & THERAPY
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2021)
Background Mesenchymal stem cell treatments in dogs have been investigated as a potential innovative alternative to current conventional therapies for a variety of conditions. So far, the precise mode of action of the MSCs has yet to be determined. T