Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Glenda M Davison"'
Autor:
Cecil J Weale, Chanelle Schroeder, Don M Matshazi, Saarah FG Davids, Rajiv T Erasmus, Andre P Kengne, Glenda M Davison, Tandi E Matsha
Publikováno v:
Journal of Diabetes Investigation, Vol 15, Iss 10, Pp 1377-1389 (2024)
Abstract Aims This study aims to investigate miR‐486‐5p and miR‐novel‐chr1_40444 expressions in dysglycemic individuals. Validating RNA‐sequencing findings in a larger sample via reverse transcription qPCR (RT‐qPCR), we aim to address glo
Externí odkaz:
https://doaj.org/article/8f0a9dad6ef54bf5a056d5a747673762
Publikováno v:
African Journal of Laboratory Medicine, Vol 12, Iss 1, Pp e1-e7 (2023)
Background: Sepsis is characterised by multi-organ failure due to an uncontrolled immune response to infection. Sepsis prevalence is increased in developing countries and requires prompt diagnosis and treatment. Reports, although controversial, sugge
Externí odkaz:
https://doaj.org/article/bd150751e50d4547b51274144612954b
Autor:
Yvonne Prince, Glenda M. Davison, Saarah F. G. Davids, Rajiv T. Erasmus, Andre P. Kengne, Lisa M. Graham, Shanel Raghubeer, Tandi E. Matsha
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 3 (2022)
The oral microbiota plays a crucial role in both systemic inflammation and metabolic syndrome (MetS), which is characterised by low-grade inflammation. Studies have analysed the gut microbiota using stool specimens from subjects with MetS; however, t
Externí odkaz:
https://doaj.org/article/815c53bf8b494b8ab8c9fd30a2b4b1aa
Autor:
Cecil J. Weale, Don M. Matshazi, Saarah F. G. Davids, Shanel Raghubeer, Rajiv T. Erasmus, Andre P. Kengne, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Aim: The influence of disease duration and anti-diabetic treatment on epigenetic processes has been described, with limited focus on interactions with microRNAs (miRNAs). miRNAs have been found to play key roles in the regulation of pathways associat
Externí odkaz:
https://doaj.org/article/9379b3e8f54f4bf597f7cfb184cd8158
Autor:
Don M. Matshazi, Cecil J. Weale, Rajiv T. Erasmus, Andre P. Kengne, Saarah F. G. Davids, Shanel Raghubeer, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
MicroRNAs are non-coding, post-transcriptional regulators of gene expression and their dysregulation has been associated with development of various diseases, including hypertension. Consequently, understanding their role in the pathogenesis and prog
Externí odkaz:
https://doaj.org/article/2dfb007e921b4233948dca301a242b23
Autor:
Don M. Matshazi, Cecil J. Weale, Rajiv T. Erasmus, Andre P. Kengne, Saarah F. G. Davids, Shanel Raghubeer, Stanton Hector, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Hypertension has a complex pathogenesis and symptoms appear in advanced disease. Dysregulation of gene expression regulatory factors like microRNAs has been reported in disease development. Identifying biomarkers which could help understand the patho
Externí odkaz:
https://doaj.org/article/f36ace27c13b41ac87f18b507fab83ac
Autor:
Cecil J. Weale, Don M. Matshazi, Saarah F. G. Davids, Shanel Raghubeer, Rajiv T. Erasmus, Andre P. Kengne, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Diagnostics, Vol 11, Iss 6, p 949 (2021)
This cross-sectional study investigated the association of miR-1299, -126-3p and -30e-3p with and their diagnostic capability for dysglycaemia in 1273 (men, n = 345) South Africans, aged >20 years. Glycaemic status was assessed by oral glucose tolera
Externí odkaz:
https://doaj.org/article/0334ae5876444e069f74c91a88b55d81
Publikováno v:
Cells, Vol 9, Iss 4, p 845 (2020)
The expression of blood group antigens varies across human populations and geographical regions due to natural selection and the influence of environment factors and disease. The red cell membrane is host to numerous surface antigens which are able t
Externí odkaz:
https://doaj.org/article/8c4baa952a9e4b97b753c0a629dcbfd5
Autor:
Tandi E. Matsha, Cecil J. Weale, Rajiv T Erasmus, Glenda M. Davison, Don M Matshazi, Shanel Raghubeer, Andre Pascal Kengne, Saarah F G Davids
Publikováno v:
Molecular Biology Reports
MicroRNAs are important in development of disease, and description of novel microRNAs adds to the pool of microRNAs that can be targeted for diagnostic and therapeutic purposes in disease. Herein, we aimed to describe novel microRNAs in a normotensiv
Autor:
Cecil J. Weale, Glenda M. Davison, Gloudina M. Hon, Andre P. Kengne, Rajiv T. Erasmus, Tandi E. Matsha
Publikováno v:
Cells, Vol 8, Iss 5, p 464 (2019)
Telomeres are DNA-tandem repeats situated at the ends of chromosomes and are responsible for genome stabilization. They are eroded by increased cell division, age and oxidative stress with shortened leucocyte telomeres (LTL) being associated with inf
Externí odkaz:
https://doaj.org/article/c14feb412bdd445f88f7f391626ddbea