Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Glenda L Evans"'
Autor:
Jae Won Choi, Shari L Sutor, Lonn Lindquist, Glenda L Evans, Benjamin J Madden, H Robert Bergen, Theresa E Hefferan, Michael J Yaszemski, Richard J Bram
Publikováno v:
PLoS Genetics, Vol 5, Iss 12, p e1000750 (2009)
Osteogenesis Imperfecta (OI) is a human syndrome characterized by exquisitely fragile bones due to osteoporosis. The majority of autosomal dominant OI cases result from point or splice site mutations in the type I collagen genes, which are thought to
Externí odkaz:
https://doaj.org/article/6198cc03b1f54266bae27fc9975b998a
Autor:
Tamara Tchkonia, Tamar Pirtskhalava, Ming Xu, Diana Jurk, Aaron P. Frank, Nathan K. LeBrasseur, Allyson K. Palmer, Roberta de Souza Santos, David G. Monroe, James L. Kirkland, Grace Casaclang-Verzosa, John R. Hawse, Joao Paulo Camporez, Glenda L. Evans, Thomas von Zglinicki, Gerald I. Shulman, Michael B. Stout, Thomas A. White, Deborah J. Clegg, Michael J. Jurczak, Ravinder J. Singh, Frederik J. Steyn, Yi Zhu, Jordan D. Miller
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Aging is associated with visceral adiposity, metabolic disorders, and chronic low-grade inflammation. 17α-estradiol (17α-E2), a naturally occurring enantiomer of 17β-estradiol (17β-E2), extends life span in male mice through unresolved mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94180832c04125f50944a45e3d657090
https://doi.org/10.1093/gerona/glv309
https://doi.org/10.1093/gerona/glv309
Autor:
Allyson K. Palmer, Michael D. Jensen, Marissa J. Schafer, Michael Torbenson, Jason M. Tonne, Michael B. Stout, Thomas A. White, Glenda L. Evans, Jan M. van Deursen, Tamara Tchkonia, James L. Kirkland, Jordan D. Miller, Daniel L. Mazula, Nathan K. LeBrasseur, Grace C Verzosa, Darren J. Baker, Yasuhiro Ikeda
Publikováno v:
Diabetes, 65, 6, pp. 1606-15
Diabetes, 65, 1606-15
Diabetes
Diabetes, 65, 1606-15
Diabetes
Item does not contain fulltext Considerable evidence implicates cellular senescence in the biology of aging and chronic disease. Diet and exercise are determinants of healthy aging; however, the extent to which they affect the behavior and accretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adce1a84d886358ff1e4a28a99e8d858
https://hdl.handle.net/2066/172511
https://hdl.handle.net/2066/172511
Autor:
Michihisa Umetani, Ryan D. Michalek, Jeffrey C. Rathmell, Erik R. Nelson, Diane Gesty-Palmer, Xiaojuan Wang, Matthew K. Howe, Glenda L. Evans, Sundeep Khosla, Donald P. McDonnell, Carolyn D. DuSell
Publikováno v:
Endocrinology. 152:4691-4705
Osteoporosis and age-related bone loss are important public health concerns. Therefore, there is a high level of interest in the development of medical interventions and lifestyle changes that reduce the incidence of osteoporosis and age-related bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0307ed95336bf03d7eb77047ef375be
https://doi.org/10.1210/en.2011-1298
https://doi.org/10.1210/en.2011-1298
Autor:
Urszula T. Iwaniec, David J. Rickard, Thomas C. Spelsberg, Katrina M. Waters, Jamie C. Hunter, John P. Lydon, Theresa E. Hefferan, Sundeep Khosla, Glenda L. Evans, Russell T. Turner, Bert W. O'Malley
Publikováno v:
Endocrinology. 149:2383-2390
The role of progesterone receptor (PR) signaling in skeletal metabolism is controversial. To address whether signaling through the PR is necessary for normal bone growth and turnover, we performed histomorphometric and microcomputed tomography analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30492e94d0ae057fd21148f33814ed1a
https://doi.org/10.1210/en.2007-1247
https://doi.org/10.1210/en.2007-1247
Autor:
Merry Jo Oursler, Russell T. Turner, David G. Monroe, Kay Rasmussen, Daniel G. Fraser, Genevieve Gorny, Steven A. Johnsen, Jan M. van Deursen, Thomas C. Spelsberg, Malayannan Subramaniam, Glenda L. Evans, David J. Rickard
Publikováno v:
Molecular and Cellular Biology. 25:1191-1199
Transforming growth factor beta-inducible early gene 1 (TIEG1) is a member of the Kruppel-like transcription factor family. To understand the physiological role of TIEG1, we generated TIEG(-/-) (null) mice and found that the TIEG(-/-) mice had increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28bd8ea8d64e7fc2a2ea9381a6836ea
https://doi.org/10.1128/mcb.25.3.1191-1199.2005
https://doi.org/10.1128/mcb.25.3.1191-1199.2005
Autor:
James T. Bronk, Glenda L. Evans, Mark E. Bolander, Thomas J. Wronski, Erik L. Ritman, Sutada Lotinun, Russell T. Turner
Publikováno v:
Journal of Bone and Mineral Research. 19:1165-1171
We examined the time course effects of continuous PTH on cortical bone and mechanical properties. PTH increased cortical bone turnover and induced intracortical porosity with no deleterious effect on bone strength. Withdrawal of PTH increased maximum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbb28e009c8c49a49ba63a8bb20628f
https://doi.org/10.1359/jbmr.040404
https://doi.org/10.1359/jbmr.040404
Autor:
Glenda L. Evans, E. Morey-Holton, Minzhi Zhang, Sutada Lotinun, Russell T. Turner, Theresa E. Hefferan
Publikováno v:
Journal of Applied Physiology. 95:1775-1780
Prologned spaceflight results in bone loss in astronauts, but there is considerable individual variation. The goal of this rat study was to determine whether gender influences bone loss during simulated weightlessness. Six-month-old Fisher 344 rats w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a384b4ade4e21f4b3c99bc593be4ece
https://doi.org/10.1152/japplphysiol.00455.2002
https://doi.org/10.1152/japplphysiol.00455.2002
Publikováno v:
Alcoholism: Clinical and Experimental Research. 27:111-117
BACKGROUND: Alcohol abuse is associated with an increased risk for osteoporosis. However, comorbidity factors may play an important role in the pathogenesis of alcohol-related bone fractures. Suboptimal mechanical loading of the skeleton, an establis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce091a9846a4f410c735fe95df0f7b44
https://doi.org/10.1111/j.1530-0277.2003.tb02730.x
https://doi.org/10.1111/j.1530-0277.2003.tb02730.x
Autor:
Kathleen M. Buhl, Glenda L. Evans, Henry J. Donahue, Russell T. Turner, Peter A. Farrell, Christopher R. Jacobs
Publikováno v:
Journal of Musculoskeletal Research. :157-169
The effect of aging on long bone mechanical properties and bone formative capacity was characterized in the male Fisher 344 rat. The femurs of rats from three age groups (4 mo., 12 mo. and 28 mo.) were tested in three-point bending to determine their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::504d84c532122897d03b3782105134d3
https://doi.org/10.1142/s0218957702000848
https://doi.org/10.1142/s0218957702000848