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pro vyhledávání: '"Glenda E. Bilder"'
Autor:
Glenda E. Bilder
Comprehension of the theories of aging requires rudimentary knowledge of oxidation and reduction reactions, protein function, cell organelles, mitosis, acquired immunity, and evolution, among other basic biological concepts. Without these fundamental
Autor:
Glenda E. Bilder
The Side Effects of Drugs Annuals forms a series of volumes in which the adverse effects of drugs and adverse reactions to them are surveyed. The series supplements the contents of Meyler's Side Effects of Drugs: the International Encyclopedia of Adv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97f4ef75f090bcd861ee98f73775c769
https://doi.org/10.1016/b978-0-444-63407-8.00041-1
https://doi.org/10.1016/b978-0-444-63407-8.00041-1
Autor:
Robert J. Leadley, Charles Kasiewski, Tara Wentz, Glenda E. Bilder, Jeffery Bostwick, Mark H. Perrone, Saul J. Needle, Betsey O’Conner, Christopher T. Dunwiddie, Lisa Byan, Kenneth Page, Helen Galczenski, Linda Merkel, Persons Paul E, Myers Michael R, Alfred P. Spada, Amin Dilip, Cuong Ly
Publikováno v:
Circulation. 99:3292-3299
Background —Platelet-derived growth factor (PDGF), a purported mediator of arterial response to injury, stimulates proliferation, chemotaxis, and matrix production by activation of its membrane receptor tyrosine kinase. Because these activities und
Autor:
Camilo J. Rojas, Glenda E. Bilder
Publikováno v:
Cardiovascular Drug Reviews. 14:380-399
Autor:
Saul J. Needle, Amin Dilip, Sheng Yuh Tang, Glenda E. Bilder, Helen Galczenski, Linda Merkel, Donald Lewis, Camilo J. Rojas, Mark H. Perrone, Marie M. Gleason
Publikováno v:
Steroids. 60:475-483
Two separate enzymatic assays were developed in order to test the selectivity of inhibitors in cholesterol biosynthesis. One assay detects inhibition of delta 5.7-sterol delta 7-reductase, the enzyme involved in the conversion of 7-dehydrocholesterol
Publikováno v:
American Journal of Physiology-Cell Physiology. 268:C1301-C1307
These studies characterized a method to measure 15-lipoxygenase (15-LO) activity in human monocytes (HMC) exposed to interleukin-4 (IL-4) and compare the activity with that of soybean 15-LO. 15-LO activity was quantitated by measuring 15-[14C]hydroxy
Publikováno v:
Drug Development Research. 29:158-166
Tyrphostins (TKI) are synthetic low molecular weight compounds which inhibit in vitro platelet-derived growth factor (PDGF) mitogenesis by blocking PDGF receptor protein tyrosine kinase activity (PDGF R-PTK). To determine whether TKIs act by this mec
Autor:
Mark H. Perrone, Susan A. Cornell, Glenda E. Bilder, John W. Ullrich, Susan Gustafson, Saul J. Needle, Amin Dilip
Publikováno v:
Journal of Lipid Research, Vol 33, Iss 11, Pp 1657-1663 (1992)
Some bisphosphonates used for the treatment of bone disorders are also potent inhibitors of squalene synthase, a critical enzyme for sterol biosynthesis. Among seven drugs tested, YM 175 (cycloheptylaminomethylene-1,1-bisphosphonic acid) was the most
Autor:
Glenda E. Bilder, D.J. Hele, Amin Dilip, R.C. Bush, Ruth Z. Rutledge, Kent Neuenswander, Saul J. Needle, Mark H. Perrone
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 353
RPR 101821 (trans-2-[4-(benzoxazol-2-yl)-phenylmethoxy] amino cyclohexane hydrochloride) is a potent cholesterol-lowering agent in rodents and marmoset. The compound inhibited rat liver microsomal squalene synthase (IC50 = 1 nM) and 7-dehydrocholeste
Publikováno v:
Atherosclerosis. 100(1)
Low current (0.25, 3 mA) stimulation through a miniature electrode cuff encased around the carotid artery of the rat was used to induce intimal hyperplasia, an important feature of the atherosclerotic plaque and a phenomenon limiting the long term su