Výsledky vyhledávání - "Glenda Cofré"

Akademický článek

Maintenance of chronicity signatures in fibroblasts isolated from recessive dystrophic epidermolysis bullosa chronic wound dressings under culture conditions

Autor: Cristian De Gregorio, Evelyng Catalán, Gabriel Garrido, Pilar Morandé, Jimena Castillo Bennett, Catalina Muñoz, Glenda Cofré, Ya-Lin Huang, Bárbara Cuadra, Paola Murgas, Margarita Calvo, Fernando Altermatt, María Joao Yubero, Francis Palisson, Andrew P. South, Marcelo Ezquer, Ignacia Fuentes

Publikováno v: Biological Research, Vol 56, Iss 1, Pp 1-16 (2023)

Abstract Background Recessive Dystrophic Epidermolysis Bullosa (RDEB) is a rare inherited skin disease caused by variants in the COL7A1 gene, coding for type VII collagen (C7), an important component of anchoring fibrils in the basement membrane of t

Externí odkaz: https://doaj.org/article/a8dd191f66034a75a30a05ba91bc6a46

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Akademický článek

Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection

Autor: Pablo Castro-Córdova, Paola Mora-Uribe, Rodrigo Reyes-Ramírez, Glenda Cofré-Araneda, Josué Orozco-Aguilar, Christian Brito-Silva, María José Mendoza-León, Sarah A. Kuehne, Nigel P. Minton, Marjorie Pizarro-Guajardo, Daniel Paredes-Sabja

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

Spores produced by Clostridioides difficile during infection are important for the recurrence of the disease. Here, Castro-Córdova et al. show that the spores gain entry into the intestinal mucosa via pathways dependent on host fibronectin and vitro

Externí odkaz: https://doaj.org/article/62ebad3827eb4925817d4a2de6d0326f

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Akademický článek

Author Correction: Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-2 (2022)

Externí odkaz: https://doaj.org/article/3ee7ca9904f34b1ea6746c9877628a1b

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Clostridioides difficilespore-entry into intestinal epithelial cells contributes to recurrence of the disease

Autor: Nigel P. Minton, Marjorie Pizarro-Guajardo, Glenda Cofré-Araneda, Daniel Paredes-Sabja, Rodrigo Reyes-Ramírez, Sarah A. Kuehne, María José Mendoza-León, Pablo Castro-Córdova, Christian Brito-Silva, Josué Orozco-Aguilar, Paola Mora-Uribe

Clostridioides difficilespores produced during infection are essential for the recurrence of the disease. However, howC. difficilespores persist in the intestinal mucosa to cause recurrent infection remains unknown. Here, we show thatC. difficilespor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b35ad816441276ed0b172eac353290f
https://doi.org/10.1101/2020.09.11.291104

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Cells from discarded dressings differentiate chronic from acute wounds in patients with Epidermolysis Bullosa

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)

Impaired wound healing complicates a wide range of diseases and represents a major cost to healthcare systems. Here we describe the use of discarded wound dressings as a novel, cost effective, accessible, and non-invasive method of isolating viable h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2fb2f64b7c860ef74107c14235d6118
http://europepmc.org/articles/PMC7492213

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Outcome of relapsing Clostridium difficile infections do not correlate with virulence-, spore- and vegetative cell-associated phenotypes

Autor: Cristian Hernández-Rocha, Fernando Gil, Robert J. Carman, Pablo Castro-Córdova, Ángela Plaza-Garrido, Daniel Paredes-Sabja, Ana María Guzmán-Durán, Valeria Olguín-Araneda, Juan A. Fuentes, Mark H. Wilcox, Manuel Álvarez-Lobos, Iván L. Calderón, Camila Miranda-Cárdenas, W. N. Fawley, Glenda Cofré-Araneda, Patricio Ibáñez

Publikováno v: Anaerobe. 36

One of the main clinical challenges of Clostridium difficile infections (CDI) is the high rate of relapse episodes. The main determinants involved in relapse of CDI include the presence of antibiotic-resistant C. difficile spores in the colonic envir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda856e74e8b1fb70f7b0c637dbef56b
https://pubmed.ncbi.nlm.nih.gov/26403333

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The Clostridium difficile exosporium cysteine (CdeC)-rich protein is required for exosporium morphogenesis and coat assembly

Autor: Marjorie Pizarro-Guajardo, Daniel Paredes-Sabja, Camila Miranda-Cárdenas, Glenda Cofré-Araneda, Jonathan Barra-Carrasco, Ángela Plaza-Garrido, Valeria Olguín-Araneda, Mahfuzur R. Sarker

Publikováno v: JOURNAL OF BACTERIOLOGY
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

Clostridium difficile is an important nosocomial pathogen that has become a major cause of antibiotic-associated diarrhea. There is a general consensus that C. difficile spores play an important role in C. difficile pathogenesis, contributing to infe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817fb38e5a3a33bfef660c4bb8702dc4
https://pubmed.ncbi.nlm.nih.gov/23794627

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Clostridium difficile spore-macrophage interactions: spore survival

Autor: Mahfuzur R. Sarker, Marjorie Pizarro-Guajardo, Glenda Cofré-Araneda, Daniel Paredes-Sabja, Christian Brito-Silva

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e43635 (2012)
PLOS ONE
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
PLoS ONE

Background: Clostridium difficile is the main cause of nosocomial infections including antibiotic associated diarrhea, pseudomembranous colitis and toxic megacolon. During the course of Clostridium difficile infections (CDI), C. difficile undergoes s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c71106ee87c984d5f129844cb035c8
http://europepmc.org/articles/PMC3428350?pdf=render

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Akademický článek

Clostridium difficile spore-macrophage interactions: spore survival.

Autor: Daniel Paredes-Sabja, Glenda Cofre-Araneda, Christian Brito-Silva, Marjorie Pizarro-Guajardo, Mahfuzur R Sarker

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e43635 (2012)

BACKGROUND: Clostridium difficile is the main cause of nosocomial infections including antibiotic associated diarrhea, pseudomembranous colitis and toxic megacolon. During the course of Clostridium difficile infections (CDI), C. difficile undergoes s

Externí odkaz: https://doaj.org/article/71d8a6caf9b445358819d841e98da8ab

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