Zobrazeno 1 - 10
of 339
pro vyhledávání: '"Glenda C Gobe"'
Autor:
Muhammad Ali Khan MPharm, Andrew J Kassianos PhD, Wendy E Hoy MD, AHM Khurshid Alam PhD, Helen G Healy MD, Glenda C Gobe PhD
Publikováno v:
Journal of Evidence-Based Integrative Medicine, Vol 27 (2022)
Chronic kidney disease (CKD) is debilitating, increasing in incidence worldwide, and a financial and social burden on health systems. Kidney failure, the final stage of CKD, is life-threatening if untreated with kidney replacement therapies. Current
Externí odkaz:
https://doaj.org/article/8587d04c760d41e09036ccbf4d5747d4
Autor:
Christudas Morais, Retnagowri Rajandram, Jade S Blakeney, Abishek Iyer, Jacky Y Suen, David W Johnson, Glenda C Gobe, David P Fairlie, David A Vesey
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248983 (2021)
Expression of the protease sensing receptor, protease activated receptor-2 (PAR2), is elevated in a variety of cancers and has been promoted as a potential therapeutic target. With the development of potent antagonists for this receptor, we hypothesi
Externí odkaz:
https://doaj.org/article/e7104d0971374f3496ae964db6472cc7
Autor:
Parth Thakor, Wenzhe Song, Ramalingam B. Subramanian, Vasudev R. Thakkar, David A. Vesey, Glenda C Gobe
Publikováno v:
Journal of Kidney Cancer and VHL, Vol 4, Iss 1, Pp 16-24 (2017)
Despite the introduction of many novel therapeutics in clinical practice, metastatic renal cell carcinoma (RCC) remains a treatment-re-sistant cancer. As red and processed meat are considered risk factors for RCC, and a vegetable-rich diet is thought
Externí odkaz:
https://doaj.org/article/1515a7247eab4e87998fcf8f8fe6e93e
Autor:
Kunyu Shen, David A Vesey, Robert J Ellis, Sharon Juliet Del Vecchio, Yeoungjee Cho, Armando Teixeira-Pinto, Michael A McGuckin, David W Johnson, Glenda C Gobe
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210246 (2019)
ObjectiveClear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer, which is difficult to treat and lacks a reliable prognostic marker. A previous study showed that the endoplasmic reticulum stress marker, glucose-regulated-
Externí odkaz:
https://doaj.org/article/51d41f0125f64d60a41b46f8e64c2c40
Autor:
Robert J Ellis, Keng Lim Ng, Hemamali Samaratunga, Sharon J Del Vecchio, Simon T Wood, Glenda C Gobe
Publikováno v:
Journal of Kidney Cancer and VHL, Vol 3, Iss 2, Pp 14-22 (2016)
Renal cell carcinoma (RCC) is the fifth most common malignancy in kidney transplant recipients, with increased risk arising due to immunosuppression. De novo RCC occurrence in kidney allografts is much less common when compared with the native kidney
Externí odkaz:
https://doaj.org/article/c94e142e952d44018003a3885b81590e
Publikováno v:
Journal of Kidney Cancer and VHL, Vol 3, Iss 1, Pp 1-11 (2016)
Although primary localised tumours of renal cell carcinoma (RCC) can be treated relatively successfully with surgery, metastatic RCC has poor prognosis because of late diagnosis and resistance to therapies. In the present study, we were interested in
Externí odkaz:
https://doaj.org/article/b58355d8ba764c0fadfbc53901e710f6
Publikováno v:
Journal of Kidney Cancer and VHL, Vol 5, Iss 3 (2018)
Sunitinib resistance is a major clinical problem hampering the treatment of renal cell carcinoma (RCC). Studies on the comprehensive characterisation of morphological, functional and molecular changes in sunitinib-resistant RCC cells are lacking. The
Externí odkaz:
https://doaj.org/article/f2d0a8d4d70d451988c055a41019eeff
Publikováno v:
Journal of Renal and Hepatic Disorders, Vol 2, Iss 1 (2018)
The Janus kinase (JAK) tyrosine kinase family and JAK/STAT signal transduction pathway may act in kidney fibrogenesis. JAK3 expression was investigated in in vitro and in vivo models of kidney fibrosis involving oxidative stress. There was a marked d
Externí odkaz:
https://doaj.org/article/52d243308c864767a7d141f82a3bc15a
Publikováno v:
Journal of Kidney Cancer and VHL, Vol 1, Iss 2, Pp 17-25 (2014)
Steroid hormones and their receptors have important roles in normal kidney biology, and alterations in their expression and function help explain the differences in development of kidney diseases, such as nephrotic syndrome and chronic kidney disease
Externí odkaz:
https://doaj.org/article/19bb5659214946df9902e95f9ae773da
Publikováno v:
Journal of Nephropathology, Vol 2, Iss 3, Pp 154-165 (2013)
Context: There is a need to define the exact benefits and contraindications of use of high-dose recombinant human erythropoietin (EPO) for its non-hematopoietic function as a cytokine that enhances tissue repair after injury. This review compares the
Externí odkaz:
https://doaj.org/article/6e3855f269064c89a8a78fe4ded43b6e