Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study

Autor: Anna H. Ou, Sara B. Rosenthal, Mazda Adli, Kazufumi Akiyama, Nirmala Akula, Martin Alda, Azmeraw T. Amare, Raffaella Ardau, Bárbara Arias, Jean-Michel Aubry, Lena Backlund, Michael Bauer, Bernhard T. Baune, Frank Bellivier, Antonio Benabarre, Susanne Bengesser, Abesh Kumar Bhattacharjee, Joanna M. Biernacka, Pablo Cervantes, Guo-Bo Chen, Hsi-Chung Chen, Caterina Chillotti, Sven Cichon, Scott R. Clark, Francesc Colom, David A. Cousins, Cristiana Cruceanu, Piotr M. Czerski, Clarissa R. Dantas, Alexandre Dayer, Maria Del Zompo, Franziska Degenhardt, J. Raymond DePaulo, Bruno Étain, Peter Falkai, Frederike Tabea Fellendorf, Ewa Ferensztajn-Rochowiak, Andreas J. Forstner, Louise Frisén, Mark A. Frye, Janice M. Fullerton, Sébastien Gard, Julie S. Garnham, Fernando S. Goes, Maria Grigoroiu-Serbanescu, Paul Grof, Oliver Gruber, Ryota Hashimoto, Joanna Hauser, Urs Heilbronner, Stefan Herms, Per Hoffmann, Andrea Hofmann, Liping Hou, Stephane Jamain, Esther Jiménez, Jean-Pierre Kahn, Layla Kassem, Tadafumi Kato, Sarah Kittel-Schneider, Barbara König, Po-Hsiu Kuo, Ichiro Kusumi, Nina Lackner, Gonzalo Laje, Mikael Landén, Catharina Lavebratt, Marion Leboyer, Susan G. Leckband, Carlos A. López Jaramillo, Glenda MacQueen, Mario Maj, Mirko Manchia, Cynthia Marie-Claire, Lina Martinsson, Manuel Mattheisen, Michael J. McCarthy, Susan L. McElroy, Francis J. McMahon, Philip B. Mitchell, Marina Mitjans, Francis M. Mondimore, Palmiero Monteleone, Caroline M. Nievergelt, Markus M. Nöthen, Tomas Novák, Urban Ösby, Norio Ozaki, Sergi Papiol, Roy H. Perlis, Claudia Pisanu, James B. Potash, Andrea Pfennig, Daniela Reich-Erkelenz, Andreas Reif, Eva Z. Reininghaus, Marcella Rietschel, Guy A. Rouleau, Janusz K. Rybakowski, Martin Schalling, Peter R. Schofield, K. Oliver Schubert, Thomas G. Schulze, Barbara W. Schweizer, Florian Seemüller, Giovanni Severino, Tatyana Shekhtman, Paul D. Shilling, Kazutaka Shimoda, Christian Simhandl, Claire M. Slaney, Alessio Squassina, Thomas Stamm, Pavla Stopkova, Sarah K. Tighe, Alfonso Tortorella, Gustavo Turecki, Eduard Vieta, Julia Volkert, Stephanie Witt, Naomi R. Wray, Adam Wright, L. Trevor Young, Peter P. Zandi, John R. Kelsoe

Publikováno v: Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)

Abstract Lithium is the gold standard treatment for bipolar disorder (BD). However, its mechanism of action is incompletely understood, and prediction of treatment outcomes is limited. In our previous multi-omics study of the Pharmacogenomics of Bipo

Externí odkaz: https://doaj.org/article/4ffae4e761e24f54b9836464e5e374c0

Alterations in the neural correlates of affective inhibitory control following cognitive behavioral therapy for depression: A Canadian biomarker integration network for depression (CAN-BIND) study

Autor: Prabhjot Dhami, Lena C. Quilty, Benjamin Schwartzmann, Rudolf Uher, Timothy A. Allen, Stefan Kloiber, Raymond W. Lam, Glenda MacQueen, Benicio N. Frey, Roumen Milev, Daniel J. Müller, Susan Rotzinger, Sidney H. Kennedy, Faranak Farzan

Publikováno v: Journal of Affective Disorders Reports, Vol 10, Iss , Pp 100413- (2022)

Background: Cognitive behavioral therapy (CBT) is an efficacious treatment for depression. CBT may in part exert its therapeutic effect by strengthening inhibitory control (IC). However, the relationship between CBT and IC has yet to be thoroughly ex

Externí odkaz: https://doaj.org/article/363038801c27463fb9a8b0a12bd6315e

Resting state fMRI scanner instabilities revealed by longitudinal phantom scans in a multi-center study

Autor: Aras Kayvanrad, Stephen R. Arnott, Nathan Churchill, Stefanie Hassel, Aditi Chemparathy, Fan Dong, Mojdeh Zamyadi, Tom Gee, Robert Bartha, Sandra E. Black, Jane M. Lawrence-Dewar, Christopher J.M. Scott, Sean Symons, Andrew D. Davis, Geoffrey B. Hall, Jacqueline Harris, Nancy J. Lobaugh, Glenda MacQueen, Cindy Woo, Stephen Strother

Publikováno v: NeuroImage, Vol 237, Iss , Pp 118197- (2021)

Quality assurance (QA) is crucial in longitudinal and/or multi-site studies, which involve the collection of data from a group of subjects over time and/or at different locations. It is important to regularly monitor the performance of the scanners o

Externí odkaz: https://doaj.org/article/7f079387e9e94e2281f5b7253a5bb97f

Pro-inflammatory markers are associated with response to sequential pharmacotherapy in major depressive disorder: a CAN-BIND-1 report

Autor: M. Ishrat Husain, Jane A. Foster, Brittany L. Mason, Sheng Chen, Haoyu Zhao, Wei Wang, Susan Rotzinger, Sakina Rizvi, Keith Ho, Raymond Lam, Glenda MacQueen, Roumen Milev, Benicio N. Frey, Daniel Müller, Gustavo Turecki, Manish Jha, Madhukar Trivedi, Sidney H. Kennedy

Publikováno v: CNS Spectrums. :1-28

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c680a8b182f87a1cc62e4fd42c2bb66
https://doi.org/10.1017/s109285292300233x

IMAGINE Network’s Mind And Gut Interactions Cohort (MAGIC) Study: a protocol for a prospective observational multicentre cohort study in inflammatory bowel disease and irritable bowel syndrome

Autor: Russell J de Souza, Sandra Zelinsky, Levinus A Dieleman, Laura Targownik, Paul Moayyedi, Jennifer Cunningham, Glenda MacQueen, Stephen Vanner, Premysl Bercik, Karen L Madsen, John D Rioux, Elena Verdú, Anthony Otley, Aida Fernandes

Publikováno v: BMJ Open, Vol 10, Iss 10 (2020)

Introduction Gut microbiome and diet may be important in irritable bowel syndrome (IBS), inflammatory bowel disease (IBD) and comorbid psychiatric conditions, but the mechanisms are unclear. We will create a large cohort of patients with IBS, IBD and

Externí odkaz: https://doaj.org/article/4cc3e581f8a548d89262476fda14c94f