Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Glen Westall"'
Autor:
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Greg Haug, Josie Larby, Collin Chia, Jade Jaffar, Glen Westall, Gurpreet Kaur Singhera, Tillie-Louise Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
Background We have previously reported arterial remodelling in patients with idiopathic pulmonary fibrosis (IPF) and suggested that endothelial-to-mesenchymal transition (EndMT) might be central to these changes. This study aims to provide evidence f
Externí odkaz:
https://doaj.org/article/b49ad27c47024587a61b641213c727bf
Autor:
Jade Jaffar, Mae Wong, Gregory A. Fishbein, Monther Alhamdoosh, Laura McMillan, Cristina Gamell-Fulla, Milica Ng, Nick Wilson, Karen Symons, Ian Glaspole, Glen Westall
Publikováno v:
ERJ Open Research, Vol 8, Iss 4 (2022)
Introduction Idiopathic pulmonary fibrosis (IPF) is a progressively fibrotic lung condition with poor prognosis. Matrix metalloproteinase-7 (MMP7) is a protein secreted by epithelial cells in IPF lungs. It is not known if MMP7 expression correlates w
Externí odkaz:
https://doaj.org/article/100231e77cc2445ab07eb39a4bc2833d
Autor:
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Collin Chia, Josie Larby, Greg Haug, Stephen Myers, Jade Jaffar, Glen Westall, Gurpreet Kaur Singhera, Tillie-Louise Hackett, James Markos, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research, Vol 8, Iss 1 (2022)
Background Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible fibrotic interstitial lung disease. We performed size-based quantitation of pulmonary arterial remodelling in IPF and examined the role of endothelial-to-mesenchymal transi
Externí odkaz:
https://doaj.org/article/cf0b599125c9433998a32829faa4515e
Autor:
Jade Jaffar, Kate Griffiths, Sara Oveissi, Mubing Duan, Michael Foley, Ian Glaspole, Karen Symons, Louise Organ, Glen Westall
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background CXCR4, a transmembrane-receptor located on epithelial cells that is activated by CXCL12, may have a role in IPF via migration of CXCR4+ fibrocytes to the lung. However, its expression has not been fully characterised in idiopathic
Externí odkaz:
https://doaj.org/article/1571d5984cf14f529cc9eb4518d48b90
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 138, Iss , Pp 111471- (2021)
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease of unknown etiology and poor prognosis. In IPF, aberrant extracellular matrix production by activated, hyperproliferative fibroblasts drives disease progression but the exact
Externí odkaz:
https://doaj.org/article/959e73ed2b684ccf9b34b50b33db7486
Autor:
Sakhee Kotecha, FRACP, Eldho Paul, BS, MS, Steve Ivulich, MPharm, Jeremy Fuller, BS, Miranda Paraskeva, FRACP, Bronwyn Levvey, RN, Gregory Snell, MD, FRACP, Glen Westall, PhD, FRACP
Publikováno v:
Transplantation Direct, Vol 7, Iss 4, p e681 (2021)
Background. Chronic lung allograft dysfunction (CLAD) is the major factor limiting survival post lung transplantation (LTx) with limited effective therapeutic options. We report our 12-y experience of antithymocyte globulin (ATG) as second-line CLAD
Externí odkaz:
https://doaj.org/article/b798737a42a64b9e8e503181222065ea
Autor:
Kaj E. C. Blokland, David W. Waters, Michael Schuliga, Jane Read, Simon D. Pouwels, Christopher L. Grainge, Jade Jaffar, Glen Westall, Steven E. Mutsaers, Cecilia M. Prêle, Janette K. Burgess, Darryl A. Knight
Publikováno v:
Pharmaceutics, Vol 12, Iss 4, p 389 (2020)
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease marked by excessive accumulation of lung fibroblasts (LFs) and collagen in the lung parenchyma. The mechanisms that underlie IPF pathophysiology are thought to reflect repeated alveola
Externí odkaz:
https://doaj.org/article/c78d3268b80d43e7a397a1b9abe04195
Publikováno v:
Internal Medicine Journal. 53:140-144
Autor:
Fiorella Calabrese, Anja C. Roden, Elizabeth Pavlisko, Francesca Lunardi, Desley Neil, Benjamin Adam, David Hwang, Martin Goddard, Gerald J. Berry, Marina Ivanovic, Jan von der Thüsen, Laure Gibault, Chieh-Yu Lin, Katharina Wassilew, Carolyn Glass, Glen Westall, Adriana Zeevi, Deborah Jo Levine, Antoine Roux
Publikováno v:
Journal of Heart and Lung Transplantation, 41(10), 1487-1500. Elsevier Inc.
Background: Routine monitoring of lung-transplanted patients is crucial for the identification of immunological and non-immunological complications. Determining the etiology of acute allograft dysfunction, particularly in alloimmune-mediated disorder
Autor:
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Collin Chia, Josie Larby, Greg Haug, Stephen Myers, Jade Jaffar, Glen Westall, Gurpreet Kaur Singhera, Tillie-Louise Hackett, James Markos, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research. :00571-2021
BackgroundIPF is a progressive, irreversible fibrotic interstitial lung disease. We performed size-based quantitation of pulmonary arterial remodelling in IPF, examined the role of EndMT and effects on lung physiology.MethodsResected lung tissues fro