Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Glen S. Kwon"'
Publikováno v:
Nano Convergence, Vol 6, Iss 1, Pp 1-15 (2019)
Abstract The Functional Upstream Domain (FUD) peptide is a potent inhibitor of fibronectin assembly and a therapeutic candidate for disorders linked with hyperdeposition of fibronectin-modulated ECM proteins. Most recently, experiments involving subc
Externí odkaz:
https://doaj.org/article/8caefb286ed241d68aa7efbadfa5af9b
Autor:
Lauren Repp, Christopher J. Unterberger, Zhengqing Ye, John B. Feltenberger, Steven M. Swanson, Paul C. Marker, Glen S. Kwon
Publikováno v:
Nanomaterials, Vol 11, Iss 10, p 2745 (2021)
Docetaxel (DTX) is among the most frequently prescribed chemotherapy drugs and has recently been shown to extend survival in advanced prostate cancer patients. However, the poor water solubility of DTX prevents full exploitation of this potent antica
Externí odkaz:
https://doaj.org/article/1aee56640a144de084baf3208fc1ab00
Publikováno v:
The AAPS Journal. 25
Autor:
Kevin R. Kozak, Glen S. Kwon, Darya Buehler, Kelsey Kasmerchak, Ho-Chul Shin, Jason R. Hasenstein
PDF file, 320K, Acute histopathologic effects of paclitaxel-containing micelles and Triolimus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624e17211e530618b7730c600a5824f8
https://doi.org/10.1158/1535-7163.22497859.v1
https://doi.org/10.1158/1535-7163.22497859.v1
Autor:
Kevin R. Kozak, Glen S. Kwon, Darya Buehler, Kelsey Kasmerchak, Ho-Chul Shin, Jason R. Hasenstein
PDF file, 109K, Toxicity of paclitaxel-containing micelles and Triolimus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0721e6dd663fba94e9e4f4e419bad6ed
https://doi.org/10.1158/1535-7163.22497853
https://doi.org/10.1158/1535-7163.22497853
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205360 (2018)
Fibronectin is a blood and extracellular matrix glycoprotein that plays important roles in wound healing and fibrosis since it controls the deposition of collagen and other extracellular matrix molecules and is a substrate for infiltrating lymphocyte
Externí odkaz:
https://doaj.org/article/ed826397e58f4734b146c19948c4e464
Publikováno v:
J Control Release
A new approach named PEG-assist is introduced for the production of drug-loaded polymeric micelles. The method is based on the use of PEG as the non-selective solvent for PEG-b-PLA in the fabrication procedure. Both hydration temperature and PEG mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d246cedd9c8fe0bf5bcfee170b8c88af
https://europepmc.org/articles/PMC9841601/
https://europepmc.org/articles/PMC9841601/
Publikováno v:
Journal of Controlled Release. 330:1004-1015
Poly(ethylene glycol)-block-poly(D,L-lactic acid) (PEG-b-PLA) and poly(ethylene glycol)-block-poly(ε-caprolactone) (PEG-b-PCL) form nano-assemblies, including micelles and nanoparticles, that increase the water solubility of anticancer drugs for inj
Autor:
Hye Jin Lee, Metti K. Gari, David R. Inman, Zachary T. Rosenkrans, Brian M. Burkel, Aeli P. Olson, Jonathan W. Engle, Reinier Hernandez, Suzanne M. Ponik, Glen S. Kwon
Publikováno v:
J Control Release
In breast cancer, the extracellular matrix (ECM) undergoes remodeling and changes the tumor microenvironment to support tumor progression and metastasis. Fibronectin (FN) assembly is an important step in the regulation of the tumor microenvironment s