Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Glen P Westall"'
Autor:
Lucy C Sullivan, Evangeline M Shaw, Sanda Stankovic, Gregory I Snell, Andrew G Brooks, Glen P Westall
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 9, Pp n/a-n/a (2019)
Abstract Gamma delta (γδ) T cells are a highly heterogeneous population of lymphocytes that exhibit innate and adaptive immune properties. Despite comprising the majority of residing lymphocytes in many organs, the role of γδ T cells in transplan
Externí odkaz:
https://doaj.org/article/f3649cfa5a254be386f6b361d42b06c7
Autor:
Sneha Sant, Misty R Jenkins, Pradyot Dash, Katherine A Watson, Zhongfang Wang, Angela Pizzolla, Marios Koutsakos, Thi HO Nguyen, Martha Lappas, Jane Crowe, Tom Loudovaris, Stuart I Mannering, Glen P Westall, Tom C Kotsimbos, Allen C Cheng, Linda Wakim, Peter C Doherty, Paul G Thomas, Liyen Loh, Katherine Kedzierska
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 9, Pp n/a-n/a (2019)
Abstract Background Although γδ T cells comprise up to 10% of human peripheral blood T cells, questions remain regarding their role in disease states and T‐cell receptor (TCR) clonal expansions. We dissected anti‐viral functions of human γδ T
Externí odkaz:
https://doaj.org/article/7ff1b72faa64454082fb640c16d1ffe8
Autor:
Lucy C Sullivan, Glen P Westall, Jacqueline M L Widjaja, Nicole A Mifsud, Thi H O Nguyen, Aislin C Meehan, Tom C Kotsimbos, Andrew G Brooks
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135972 (2015)
The human cytomegalovirus (CMV) immune evasion protein, UL40, shares an identical peptide sequence with that found in the leader sequence of many human leukocyte antigen (HLA)-C alleles and when complexed with HLA-E, can modulate NK cell functions vi
Externí odkaz:
https://doaj.org/article/c545f4703e9e458cb6880be00b31d3eb
Autor:
Thi H O Nguyen, Glen P Westall, Tara E Bull, Aislin C Meehan, Nicole A Mifsud, Tom C Kotsimbos
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56042 (2013)
Human Cytomegalovirus (CMV) reactivation continues to influence lung transplant outcomes. Cross-reactivity of anti-viral memory T cells against donor human leukocyte antigens (HLA) may be a contributing factor. We identified cross-reactive HLA-A*02:0
Externí odkaz:
https://doaj.org/article/bbfc30732a794d5eb7ec34b35dd7ed6a
Autor:
Aislin C Meehan, Nicole A Mifsud, Thi H O Nguyen, Bronwyn J Levvey, Greg I Snell, Tom C Kotsimbos, Glen P Westall
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60144 (2013)
Lung transplantation is a recognised treatment for patients with end stage pulmonary disease. Transplant recipients receive life-long administration of immunosuppressive drugs that target T cell mediated graft rejection. However little is known of th
Externí odkaz:
https://doaj.org/article/4aadebe06b06469092c4303ef69ad2d1
Autor:
Natasha Lannin, Emma Schneider, Jenny-Maree Marshall, Shenae O’Mahony, Glen Phillip Westall, Anoo Bhopti
Publikováno v:
BMJ Paediatrics Open, Vol 7, Iss 1 (2023)
Introduction Following lung transplantation, it is unknown how children/adolescents self-assess their performance in everyday activities, importance of these activities, and whether resumption of everyday activities influences self-reported quality o
Externí odkaz:
https://doaj.org/article/8229108136004ffc88472ce789f2171e
Autor:
Jenny Li, MD, Bradley J. Gardiner, MD, Sanda Stankovic, PhD, Clare V. L. Oates, BSc (Hons), Yvonne Cristiano, RN, Bronwyn J. Levvey, RN, Andrew G. Brooks, PhD, Gregory I. Snell, MD, Glen P. Westall, MD, PhD, Lucy C. Sullivan, PhD
Publikováno v:
Transplantation Direct, Vol 9, Iss 7, p e1501 (2023)
Background:. Cytomegalovirus (CMV) infection causes significant morbidity and mortality in lung transplant recipients. Current guidelines use pretransplant donor and recipient CMV serostatus to predict the risk of subsequent CMV replication and lengt
Externí odkaz:
https://doaj.org/article/909ef328f1b14bdc8e7c6be2d17bddd9
Autor:
Joshua D. Birnie, Tanveer Ahmed, Sarah E. Kidd, Glen P. Westall, Gregory I. Snell, Anton Y. Peleg, Catherine Orla Morrissey
Publikováno v:
Journal of Fungi, Vol 10, Iss 2, p 95 (2024)
Aspergillus fumigatus can cause different clinical manifestations/phenotypes in lung transplant (LTx) recipients and patients with chronic respiratory diseases. It can also precipitate chronic lung allograft dysfunction (CLAD) in LTx recipients. Many
Externí odkaz:
https://doaj.org/article/10aa9cc5b3d441a6b43149f6e1ce7d5d
Autor:
Luca Hensen, Patricia T. Illing, E. Bridie Clemens, Thi H. O. Nguyen, Marios Koutsakos, Carolien E. van de Sandt, Nicole A. Mifsud, Andrea T. Nguyen, Christopher Szeto, Brendon Y. Chua, Hanim Halim, Simone Rizzetto, Fabio Luciani, Liyen Loh, Emma J. Grant, Phillipa M. Saunders, Andrew G. Brooks, Steve Rockman, Tom C. Kotsimbos, Allen C. Cheng, Michael Richards, Glen P. Westall, Linda M. Wakim, Thomas Loudovaris, Stuart I. Mannering, Michael Elliott, Stuart G. Tangye, David C. Jackson, Katie L. Flanagan, Jamie Rossjohn, Stephanie Gras, Jane Davies, Adrian Miller, Steven Y. C. Tong, Anthony W. Purcell, Katherine Kedzierska
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The immunology of Indigenous populations is generally understudied outside the context of diseases that are prevalent in these communities. Here the authors identify prevalence of influenza CD8+ T cell epitopes in an Indigenous Australian population
Externí odkaz:
https://doaj.org/article/a3a6a4c017e544c7b83819f5cde0c3d5
Autor:
Kieran Halloran, Martina Mackova, Michael D Parkes, Alim Hirji, Justin Weinkauf, Irina L Timofte, Greg I Snell, Glen P Westall, Robert Lischke, Andrea Zajacova, Jan Havlin, Ramsey Hachem, Daniel Kreisel, Deborah Levine, Bartosz Kubisa, Maria Piotrowska, Stephen Juvet, Shaf Keshavjee, Peter Jaksch, Walter Klepetko, Philip F Halloran
Publikováno v:
The Journal of Heart and Lung Transplantation. 41:1689-1699
Many lung transplants fail due to chronic lung allograft dysfunction (CLAD). We recently showed that transbronchial biopsies (TBBs) from CLAD patients manifest severe parenchymal injury and dedifferentiation, distinct from time-dependent changes. The