Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Glen P, Carter"'
Autor:
Yi Nong, Eike Steinig, Georgina L. Pollock, George Taiaroa, Glen P. Carter, Ian R. Monk, Stanley Pang, Denise A. Daley, Geoffrey W. Coombs, Brian M. Forde, Patrick N. A. Harris, Norelle L. Sherry, Benjamin P. Howden, Shivani Pasricha, Sarah L. Baines, Deborah A. Williamson
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract The past decade has seen an increase in the prevalence of sequence type (ST) 45 methicillin-resistant Staphylococcus aureus (MRSA), yet the underlying drivers for its emergence and spread remain unclear. To better understand the worldwide di
Externí odkaz:
https://doaj.org/article/d738cf3544a04aedbcf99c1a4ea67914
Autor:
Ouli Xie, Jacqueline M. Morris, Andrew J. Hayes, Rebecca J. Towers, Magnus G. Jespersen, John A. Lees, Nouri L. Ben Zakour, Olga Berking, Sarah L. Baines, Glen P. Carter, Gerry Tonkin-Hill, Layla Schrieber, Liam McIntyre, Jake A. Lacey, Taylah B. James, Kadaba S. Sriprakash, Scott A. Beatson, Tadao Hasegawa, Phil Giffard, Andrew C. Steer, Michael R. Batzloff, Bernard W. Beall, Marcos D. Pinho, Mario Ramirez, Debra E. Bessen, Gordon Dougan, Stephen D. Bentley, Mark J. Walker, Bart J. Currie, Steven Y. C. Tong, David J. McMillan, Mark R. Davies
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Streptococcus dysgalactiae subsp. equisimilis (SDSE) is an emerging cause of human infection with invasive disease incidence and clinical manifestations comparable to the closely related species, Streptococcus pyogenes. Through systematic ge
Externí odkaz:
https://doaj.org/article/64c2683511e049649c96119d191110c7
Publikováno v:
Microorganisms, Vol 12, Iss 7, p 1479 (2024)
Despite being considered a normal flora, Providencia alcalifaciens can cause diarrhea. In a previous study, strain 2939/90, obtained from a diarrheal patient, caused invasion and actin condensation in mammalian cells, and diarrhea in a rabbit model.
Externí odkaz:
https://doaj.org/article/0dd184bf33f746f5b0300ff4a445c8eb
Autor:
Liam K. R. Sharkey, Romain Guerillot, Calum J. Walsh, Adrianna M. Turner, Jean Y. H. Lee, Stephanie L. Neville, Stephan Klatt, Sarah L. Baines, Sacha J. Pidot, Fernando J. Rossello, Torsten Seemann, Hamish E. G. McWilliam, Ellie Cho, Glen P. Carter, Benjamin P. Howden, Christopher A. McDevitt, Abderrahman Hachani, Timothy P. Stinear, Ian R. Monk
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTAmong the 16 two-component systems in the opportunistic human pathogen Staphylococcus aureus, only WalKR is essential. Like the orthologous systems in other Bacillota, S. aureus WalKR controls autolysins involved in peptidoglycan remodeling a
Externí odkaz:
https://doaj.org/article/b925679724c74489887fb31d58cddb66
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Acinetobacter baumannii is a nosocomial multidrug-resistant pathogen that specifically colonizes and infects patients in intensive care units (ICUs). Genome plasticity of A. baumannii may contribute to the rapid development of A. baumannii r
Externí odkaz:
https://doaj.org/article/5a484ce33d6d43c280dbbc7bb1e9318d
Autor:
Noel P. Pitcher, Jitendra R. Harjani, Yichao Zhao, Jianwen Jin, Daniel R. Knight, Lucy Li, Papanin Putsathit, Thomas V. Riley, Glen P. Carter, Jonathan B. Baell
Publikováno v:
ACS Omega, Vol 7, Iss 8, Pp 6737-6759 (2022)
Externí odkaz:
https://doaj.org/article/2cb2c9b176f449c28e66dba1e8d0cf30
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1530 (2023)
Antiretrovirals (ARVs) are a highly effective therapy for treatment and prevention of HIV infection, when administered as prescribed. However, adherence to lifelong ARV regimens poses a considerable challenge and places HIV patients at risk. Long-act
Externí odkaz:
https://doaj.org/article/94384584fd5f4aa5bf15e2bd634b06a2
Autor:
Michelle Y-H Lee, Georges Khoury, Moshe Olshansky, Secondo Sonza, Glen P. Carter, James McMahon, Timothy P. Stinear, Stephen J. Turner, Sharon R. Lewin, Damian F. J. Purcell
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Latent HIV-1 provirus in infected individuals on suppressive therapy does not always remain transcriptionally silent. Both HIV-1 LTR and human gene promoter derived transcriptional events can contribute HIV-1 sequences to the mRNA produced in the cel
Externí odkaz:
https://doaj.org/article/c2f040ad12cf4dec9245f544d8ddf3bf
Autor:
Kate A. Worthing, Anja Werno, Ramon Pink, Liam McIntyre, Glen P. Carter, Deborah A. Williamson, Mark R. Davies
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 5, Pp 841-848 (2020)
A 3-month outbreak of invasive group A Streptococcus disease at an eldercare facility, in which 5 persons died, was biphasic. Although targeted chemoprophylaxis contained the initial outbreak, a second phase of the outbreak occurred after infection c
Externí odkaz:
https://doaj.org/article/995a9ba24c934394a71f7205a8f07958
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 303 (2023)
Drug targeting is necessary to deliver drugs to a specific site of action at a rate dictated by therapeutic requirements. The pharmacological action of a drug can thereby be optimised while minimising adverse effects. Numerous colonic drug delivery s
Externí odkaz:
https://doaj.org/article/f5c66296317f42a89799f9685098aeb0