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Pharmacodynamics of telavancin (TD-6424), a novel bactericidal agent, against gram-positive bacteria
Autor:
Jeng-Pyng Shaw, Koné Kaniga, Robert A. Skinner, Noe Reyes, John L. Pace, Julia McCullough, J. Kevin Judice, Roger Thomas, Sharath S. Hegde, Glen Obedencio, Nicole Vanasse, Tania Wiens
Publikováno v:
Antimicrobial agents and chemotherapy. 48(8)
Telavancin (TD-6424) is a novel lipoglycopeptide that produces rapid and concentration-dependent killing of clinically relevant gram-positive organisms in vitro. The present studies evaluated the in vivo pharmacodynamics of telavancin in the mouse ne