Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Glen M, Boyle"'
Autor:
Kevin Hendrawan, Kelly M Brooks, Pei-Yi Yap, Blake Ferguson, Motoko Koyama, Herlina Handoko, Jenny Johns, Natasa Broit, Praphaporn Stewart, Daniel Shelley, Tracey McMahon, Yi Chieh Lim, Giovanni Appendino, Jason K Cullen, Zara C Bruce, Steven M Ogbourne, Paul W Reddell, Glen M Boyle, Peter G Parsons, Jacinta L Simmons, Emily S Wilson, Marjorie M A de Souza, Tam Hong Nguyen, Alberto Pagani, Victoria A Gordon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Tigilanol tiglate (TT) is a protein kinase C (PKC)/C1 domain activator currently being developed as an intralesional agent for the treatment of various (sub)cutaneous malignancies. Previous work has shown that intratumoral (I.T.) injection
Externí odkaz:
https://doaj.org/article/756c2bca74d94c10bc6e590de097d302
Autor:
Pei-Yi Yap, Blake Ferguson, Motoko Koyama, Herlina Handoko, Jenny Johns, Praphaporn Stewart, Jason K Cullen, Zara C Bruce, Steven M Ogbourne, Paul W Reddell, Glen M Boyle, Peter G Parsons
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/666166a94c5149478dd75a58660a857a
Autor:
Priscila O. de Lima, Natasa Broit, Johnson D. Huang, Jae H. Lim, Damien J. Gardiner, Ian S. Brown, Benedict J. Panizza, Glen M. Boyle, Fiona Simpson
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionCutaneous squamous cell carcinoma of the head and neck (cSCCHN) can metastasize by invading nerves and spread toward the central nervous system. This metastatic process is called perineural invasion (PNI) and spread (PNS). An in vivo scia
Externí odkaz:
https://doaj.org/article/2c5024cdd8094be2929d27f498303ef0
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The acquisition of resistance to anoikis, the cell death induced by loss of adhesion to the extracellular matrix, is an absolute requirement for the survival of disseminating and circulating tumour cells (CTCs), and for the seeding of metastatic lesi
Externí odkaz:
https://doaj.org/article/941fbfc426b34ddfa01f6bbf58601541
Autor:
Timothy J. Liu, Lynlee L. Lin, Erin McMeniman, Jason Wu, Yung-Ching Kao, Snehlata Kumari, Glen M. Boyle, James W. Wells, H. Peter Soyer, Jazmina L. Gonzalez-Cruz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Inflammatory skin conditions are the 4th leading cause of non-fatal health burden in the general population worldwide. The diagnosis of skin lesions due to systemic drug reactions, viral or bacterial exanthems, or in patients with psoriasis, atopic d
Externí odkaz:
https://doaj.org/article/3f05e85150b14022b82fa478fff2af06
Publikováno v:
Marine Drugs, Vol 21, Iss 4, p 253 (2023)
Human skin needs additional protection from damaging ultraviolet radiation (UVR: 280–400 nm). Harmful UVR exposure leads to DNA damage and the development of skin cancer. Available sunscreens offer chemical protection from detrimental sun radiation
Externí odkaz:
https://doaj.org/article/b79b29c8ff00416abbb35a8c232f828e
Autor:
Jason K. Cullen, Glen M. Boyle, Pei-Yi Yap, Stefan Elmlinger, Jacinta L. Simmons, Natasa Broit, Jenny Johns, Blake Ferguson, Lidia A. Maslovskaya, Andrei I. Savchenko, Paul Malek Mirzayans, Achim Porzelle, Paul V. Bernhardt, Victoria A. Gordon, Paul W. Reddell, Alberto Pagani, Giovanni Appendino, Peter G. Parsons, Craig M. Williams
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The long-standing perception of Protein Kinase C (PKC) as a family of oncoproteins has increasingly been challenged by evidence that some PKC isoforms may act as tumor suppressors. To explore the hypothesis that activation, rather than inhib
Externí odkaz:
https://doaj.org/article/48af2e8d91fb499798d2ad925238a5a8
Autor:
Elena S. Martens‐Uzunova, Gina D. Kusuma, Stefania Crucitta, Hong Kiat Lim, Crystal Cooper, James E. Riches, Arun Azad, Takahiro Ochiya, Glen M. Boyle, Melissa C. Southey, Marzia Del Re, Rebecca Lim, Grant A. Ramm, Guido W. Jenster, Carolina Soekmadji
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 10, Pp n/a-n/a (2021)
Abstract Proliferation and survival of prostate cancer cells are driven by the androgen receptor (AR) upon binding to androgen steroid hormones. Manipulating the AR signalling axis is the focus for prostate cancer therapy; thus, it is crucial to unde
Externí odkaz:
https://doaj.org/article/7efbb642abe94c38ab380b2fe97905c8
Autor:
Karina D. Hamilton, Daniel Czajkowski, Nicolas J. Kong, Trong D. Tran, Kirk R. Gustafson, Gary Pauly, Glen M. Boyle, Jacinta L. Simmons, Robert Steadman, Ryan Moseley, Peter R. Brooks, Steven M. Ogbourne, Fraser D. Russell
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1604 (2022)
Bioactivity-guided fractionation was used to isolate two compounds, tomentosenol A (1) and torellianone A (2), from a cerumen extract from Tetragonula carbonaria. The anti-fibrotic activity of these compounds was examined using human cultured neonata
Externí odkaz:
https://doaj.org/article/58110c04aace4746b4251c0bac3cea21
Autor:
Yongbo Xue, Andrei I. Savchenko, Kylie A. Agnew-Francis, Jared A. Miles, Tina Holt, Hieng Lu, Sharon Chow, Paul I. Forster, Glen M. Boyle, Benjamin P. Ross, Katja Fischer, Andrei G. Kutateladze, Craig M. Williams
Publikováno v:
Journal of Natural Products. 86:490-497
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a3474d6b9522346bd8c1aca238e70a2
https://doi.org/10.1021/acs.jnatprod.2c01037
https://doi.org/10.1021/acs.jnatprod.2c01037