Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Glen C. Ulett"'
Autor:
Nguyen Thi Khanh Nhu, M. Arifur Rahman, Kelvin G. K. Goh, Seung Jae Kim, Minh-Duy Phan, Kate M. Peters, Laura Alvarez-Fraga, Steven J. Hancock, Chitra Ravi, Timothy J. Kidd, Matthew J. Sullivan, Katharine M. Irvine, Scott A. Beatson, Matthew J. Sweet, Adam D. Irwin, Jana Vukovic, Glen C. Ulett, Sumaira Z. Hasnain, Mark A. Schembri
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Bacteria adapt to selective pressure in their immediate environment in multiple ways. One mechanism involves the acquisition of independent mutations that disable or modify a key pathway, providing a signature of adaptation via convergent ev
Externí odkaz:
https://doaj.org/article/0c835c379e9d49008c3aba49b38fd4c2
Autor:
Victoria Ozberk, Mehfuz Zaman, Ailin Lepletier, Sharareh Eskandari, Jacqualine Kaden, Jamie-Lee Mills, Ainslie Calcutt, Jessica Dooley, Yongbao Huo, Emma L. Langshaw, Glen C. Ulett, Michael R. Batzloff, Michael F. Good, Manisha Pandey
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Mucosally active subunit vaccines are an unmet clinical need due to lack of licensed immunostimulants suitable for vaccine antigens. Here, we show that intranasal administration of liposomes incorporating: the Streptococcus pyogenes peptide
Externí odkaz:
https://doaj.org/article/6a7065b93c674ba3bb43501a205f2afc
Publikováno v:
Journal of Immunology Research, Vol 2024 (2024)
Antigenic cell fragments, pathogen-associated molecular patterns, and other immunostimulants in bacterial lysates or extracts may induce local and systemic immune responses in specific and nonspecific paradigms. Based on current knowledge, this revie
Externí odkaz:
https://doaj.org/article/d826d9bd9c744a2ea704ac7f01b8d124
Autor:
Matthew J. Sullivan, Darren Prince, Kelvin G. K. Goh, Lahiru Katupitiya, Dean Gosling, Michael R. Crowley, David K. Crossman, Glen C. Ulett
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Streptococcus agalactiae, also known as Group B Streptococcus (GBS) is a frequent cause of infections, including bacteraemia and other acute diseases in adults and immunocompromised individuals. We developed a novel system to study GBS withi
Externí odkaz:
https://doaj.org/article/ba104a9df20644099df98bfad98b3b28
Autor:
Brian R. Varghese, Kelvin G. K. Goh, Devika Desai, Dhruba Acharya, Collin Chee, Matthew J. Sullivan, Glen C. Ulett
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Streptococcus agalactiae, also known as group B Streptococcus, is an important human and animal pathogen. Zinc (Zn) is an essential trace element for normal bacterial physiology but intoxicates bacteria at high concentrations. Molecular systems for Z
Externí odkaz:
https://doaj.org/article/7317dbff37894546a38d7dc6c4ae4c47
Autor:
Matthew J. Sullivan, Kelvin G. K. Goh, Ruby Thapa, Debasish Chattopadhyay, Deepak S. Ipe, Benjamin L. Duell, Lahiru Katupitiya, Dean Gosling, Dhruba Acharya, Glen C. Ulett
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 3015-3027 (2021)
Streptococcus agalactiae glyceraldehyde 3-phosphate dehydrogenase (GAPDH), encoded by gapC, is a glycolytic enzyme that is associated with virulence and immune-mediated protection. However, the role of GAPDH in cellular cytokine responses to S. agala
Externí odkaz:
https://doaj.org/article/75affdcbde0645aa8fa80d903f557a0a
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010607 (2022)
Metals such as copper (Cu) and zinc (Zn) are important trace elements that can affect bacterial cell physiology but can also intoxicate bacteria at high concentrations. Discrete genetic systems for management of Cu and Zn efflux have been described i
Externí odkaz:
https://doaj.org/article/72753f065f6940c58b7e124df326d065
Autor:
Laura Alvarez-Fraga, Minh-Duy Phan, Kelvin G. K. Goh, Nguyen Thi Khanh Nhu, Steven J. Hancock, Luke P. Allsopp, Kate M. Peters, Brian M. Forde, Leah W. Roberts, Matthew J. Sullivan, Makrina Totsika, Scott A. Beatson, Glen C. Ulett, Mark A. Schembri
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Many antibiotic resistant uropathogenic Escherichia coli (UPEC) strains belong to clones defined by their multilocus sequence type (ST), with ST131 being the most dominant. Although we have a good understanding of resistance development to f
Externí odkaz:
https://doaj.org/article/604971ebb7e74b8980f09a7b03594636
Autor:
Anu Chacko, Ali Delbaz, Indra N. Choudhury, Tanja Eindorf, Megha Shah, Christopher Godfrey, Matthew J. Sullivan, James A. St John, Glen C. Ulett, Jenny A. K. Ekberg
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Streptococcus agalactiae causes neonatal meningitis and can also infect the adult central nervous system (CNS). S. agalactiae can cross the blood-brain barrier but may also reach the CNS via other paths. Several species of bacteria can directly invad
Externí odkaz:
https://doaj.org/article/4904bfb84c714f9aa17df353db463f2f
Autor:
Frank Stadler, Talia Arjona, Glenn Beaumont, Charlotte Bradley, Alyssa Budd, Pedro Busana, Mathew Clatworthy, Jodie Fitz-Gibbon, Kelvin G. K. Goh, Matt Hayes, Kylie Heather, Aisha Lawton, Mike McAuley, Sarah Onoprienko, Aliana Rogers, Tiana Schimpf, Matthew J. Sullivan, Glen C. Ulett, Jessica Warren, Bridget Woodman, Zac Zerafa
Publikováno v:
Citizen Science: Theory and Practice, Vol 6, Iss 1 (2021)
This case study describes how high school students can participate in research, development, and testing of real-life solutions for society’s most intractable problems. In modern warfare, civilians make up most of the casualties, and conflict-affec
Externí odkaz:
https://doaj.org/article/c04101a0ea8b4c8392e5954f7a4b64fd