Zobrazeno 1 - 10
of 254
pro vyhledávání: '"Glen A Doherty"'
Autor:
Margaret eDunne, Ciara eRyan, Miriam eTosetto, Bláthnaid eNolan, Robert eGeraghty, Des C Winter, Ronan eO'Connell, John eHyland, Glen A Doherty, Kieran eSheahan, Elizabeth J Ryan, Jean M Fletcher
Publikováno v:
Frontiers in Oncology, Vol 6 (2016)
T cell infiltration into colorectal tumours has been shown to correlate with improved patient outcomes. However, more detailed information on the make-up and relationships between the infiltrating T cell subsets is lacking. We therefore correlated th
Externí odkaz:
https://doaj.org/article/5d7d01c0a28f4ce3aa6c15c8d6ade311
Autor:
Glen A Doherty, Mark A Peppercorn
Publikováno v:
Clinical and Experimental Gastroenterology, Vol 2009, Iss default, Pp 139-147 (2009)
Glen A Doherty, Mark A PeppercornCenter for Inflammatory Bowel Disease, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston MA, USAAbstract: 5-aminosalicyclates (5-ASA) remain a key first-line therapy for patients with ulcerative
Externí odkaz:
https://doaj.org/article/4567b738707c454ab861a0642926bfbf
Autor:
Clíona Ní Chonnacháin, Emma L. Feeney, Clare Gollogly, Denis C. Shields, Christine E. Loscher, Paul D. Cotter, Nessa Noronha, Roisin Stack, Glen A. Doherty, Eileen R. Gibney
Publikováno v:
Gut Microbiome, Vol 5 (2024)
Bovine dairy foods provide several essential nutrients. Fermented bovine dairy foods contain additional compounds, increasing their potential to benefit gastrointestinal health. This review explores the effects of dairy consumption on the gut microbi
Externí odkaz:
https://doaj.org/article/2d44199ab58c4535ae46083beb97581d
Autor:
Vanessa Zaiatz-Bittencourt, Fiona Jones, Miriam Tosetto, Caitriona Scaife, Gerard Cagney, Evan Jones, Glen A. Doherty, Elizabeth J. Ryan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The gut microbiota regulates chronic inflammation and has been implicated in the pathogenesis of a broad spectrum of disease including autoimmunity and cancer. Microbial short-chain fatty acids (SCFAs) e.g., butyrate have demonstrated immuno
Externí odkaz:
https://doaj.org/article/7ea9284ffa394ea0a9f11c4623309226
Autor:
Jayne Doherty, Neil O Morain, Roisin Stack, Miriam Tosetto, Rosanna Inzitiari, Sophie O Reilly, Lili Gu, Juliette Sheridan, Garret Cullen, Edel Mc Dermott, Maire Buckley, Gareth Horgan, Hugh Mulcahy, Margaret Walshe, Elizabeth J Ryan, Virginie Gautier, John Prostko, Edwin Frias, David Daghfal, Peter Doran, Colm O Morain, Glen A Doherty
Publikováno v:
Journal of Crohn's and Colitis.
Background and Aims Patients with inflammatory bowel disease [IBD] have an attenuated response to initial COVID-19 vaccination. We sought to characterize the impact of IBD and its treatment on responses after the third vaccine against SARS-CoV-2. Met
Publikováno v:
Inflamm Intest Dis
Inflammatory Intestinal Diseases, Pp 1-6 (2021)
Inflammatory Intestinal Diseases, Pp 1-6 (2021)
Background: Crohn’s disease (CD) is a chronic inflammatory disorder affecting the gastrointestinal tract with disease behaviour based on the depth and severity of mucosal injury. Cumulative injury can result in complications including stricture for
Autor:
Garret Cullen, Neil O' Morain, Roisin Stack, Cillian De Gascun, Jayne Doherty, Elizabeth J. Ryan, Glen A. Doherty, Sean Fennessy
Publikováno v:
Alimentary Pharmacology & Therapeutics
Summary Background Poor immune responses are frequently observed in patients with inflammatory bowel disease (IBD) receiving established vaccines; risk factors include immunosuppressants and active disease. Aims To summarise available information reg
Publikováno v:
British Journal of Dermatology. 188:442-443
First report of alopecia areata responding to the selective JAK1 inhibitor filgotinib. This case is a patient with coinciding Crohn’s disease that had failed multiple biologics. It serves as a real-world example of how shared decision making betwee
Publikováno v:
Inflammatory Bowel Diseases
The cells of the immune system are highly dynamic, constantly sensing and adapting to changes in their surroundings. Complex metabolic pathways govern leukocytes’ ability to fine-tune their responses to external threats. Mammalian target of rapamyc
Publikováno v:
Journal of Crohn's & Colitis
Background and Aims Inflammatory bowel diseases [IBD], comprising Crohn’s disease [CD] and ulcerative colitis [UC], are chronic conditions characterized by severe dysregulation of innate and adaptive immunity resulting in the destruction of the int