Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Glen, Otto"'
Autor:
Alex T Nielsen, Nadia A Dolganov, Thomas Rasmussen, Glen Otto, Michael C Miller, Stephen A Felt, Stéphanie Torreilles, Gary K Schoolnik
Publikováno v:
PLoS Pathogens, Vol 6, Iss 9, p e1001102 (2010)
A fundamental, but unanswered question in host-pathogen interactions is the timing, localization and population distribution of virulence gene expression during infection. Here, microarray and in situ single cell expression methods were used to study
Externí odkaz:
https://doaj.org/article/3486c90edb2b40dcb9e23dfdd89ec4fe
Autor:
Alex Toftgaard Nielsen, Nadia A Dolganov, Glen Otto, Michael C Miller, Cheng Yen Wu, Gary K Schoolnik
Publikováno v:
PLoS Pathogens, Vol 2, Iss 10, p e109 (2006)
Vibrio cholerae causes a severe diarrhoeal disease by secreting a toxin during colonization of the epithelium in the small intestine. Whereas the initial steps of the infectious process have been intensively studied, the last phases have received lit
Externí odkaz:
https://doaj.org/article/188187e45f8f41dd8b61ba519d3de40f
Publikováno v:
PLoS Pathogens, Vol 2, Iss 1, p e3 (2006)
Listeria monocytogenes causes invasive disease by crossing the intestinal epithelial barrier. This process depends on the interaction between the bacterial surface protein Internalin A and the host protein E-cadherin, located below the epithelial tig
Externí odkaz:
https://doaj.org/article/d28cbe5a0d534c449a37455317a0712c
Laboratory Animal Medicine, Third Edition, is a fully revised publication from the American College of Laboratory Medicine's acclaimed blue book series. It presents an up-to-date volume that offers the most thorough coverage of the biology, health, a
Publikováno v:
Molecular Carcinogenesis. 52:997-1006
Calorie restriction (CR) prevents obesity and has potent anticancer effects associated with altered hormones and cytokines. We tested the hypothesis that CR inhibits MC38 mouse colon tumor cell growth through modulation of hormone-stimulated nuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30c65081bc55fbdcbc8dad04e82094ae
https://doi.org/10.1002/mc.21940
https://doi.org/10.1002/mc.21940
Autor:
Andrew Brenner, Claudio J. Conti, Rebecca E. De Angel, Glen Otto, Stephen D. Hursting, Karrie E. Wheatley, Linda A. deGraffenried
Publikováno v:
Molecular Carcinogenesis. 52:446-458
The prevalence of obesity, an established risk and progression factor for postmenopausal breast cancer, remains high in US women. Activation of Akt/mammalian target of rapamycin (mTOR) signaling plays a key role in the obesity-breast cancer link. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d920d0cf2e664991151f27ba787f7e8a
https://doi.org/10.1002/mc.21878
https://doi.org/10.1002/mc.21878
Autor:
Lauren Malone, Glen Otto, Jason A. Goldberg, Elizabeth A. Daniels, Graham W. Brown, Stephen D. Hursting, Susan M. Fischer, Laura M. Lashinger
Publikováno v:
Cancer Prevention Research. 4:1041-1051
Etiologic factors for pancreatic cancer, the 4th deadliest malignant neoplasm in the United States, include obesity and abnormal glucose metabolism. Calorie restriction (CR) and rapamycin each affect energy metabolism and cell survival pathways via i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1305a530fe7123ab38de414c29d3701
https://doi.org/10.1158/1940-6207.capr-11-0023
https://doi.org/10.1158/1940-6207.capr-11-0023
Human risks of acquiring a zoonotic disease from animals used in biomedical research have declined over the last decade because higher quality research animals have defined microbiologic profiles. Even with diminished risks, the potential for exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::148257f1e589b4796795bbdf20e35b8e
https://doi.org/10.1016/b978-0-12-409527-4.00028-6
https://doi.org/10.1016/b978-0-12-409527-4.00028-6
A. Major Taxonomic and Historical Considerations The laboratory rat, Rattus norvegicus, is within the order Rodentia and family Muridae. The genus Rattus contains more than 130 species; however, the Norway rat, R. norvegicus, and the black rat, R. ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c3784039e950843997039c940578f89
https://doi.org/10.1016/b978-0-12-409527-4.00004-3
https://doi.org/10.1016/b978-0-12-409527-4.00004-3