Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Glen, Le Flahec"'
Autor:
Numa Deydier, Hélène Jantzem, Zarrin Alavi, Glen Le Flahec, Marine Robert, Anne‐Marie Roguedas‐Contios, Emilie Brenaut, Laurent Misery, Greta Gourier
Publikováno v:
JEADV Clinical Practice, Vol 2, Iss 2, Pp 363-365 (2023)
Abstract Duloxetine is a serotonin and norepinephrine reuptake inhibitor. Some rare duloxetine‐induced hypersensitivity skin reactions have been reported. We report a case of acute generalized exanthematous pustulosis potentially induced by duloxet
Externí odkaz:
https://doaj.org/article/877cd696f1d94bf9869a89134b412544
Autor:
Marine Robert, MD, Marie-Anne Couturier, MD, Nicolas Ortonne, MD, PhD, Glen Le Flahec, MD, Céline Bryer-Le Breton, MD, Flavien Huet, MD, PhD, Laurent Misery, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 33, Iss , Pp 17-19 (2023)
Externí odkaz:
https://doaj.org/article/21438aa36bd549a197b5221ee14573f7
Evaluation of a Rapid, Fully Automated Platform for Detection of BRAF and NRAS Mutations in Melanoma
Autor:
Fanny Barel, Briac Guibourg, Laetitia Lambros, Glen Le Flahec, Pascale Marcorelles, Arnaud Uguen
Publikováno v:
Acta Dermato-Venereologica, Vol 98, Iss 1, Pp 44-49 (2017)
BRAF and NRAS genetic analyses are time-consuming and can delay treatment choices in patients with metastatic melanomas presenting with acute deterioration. We compared the rapid, real-time, fully automated molecular diagnosis platform Idylla™ with
Externí odkaz:
https://doaj.org/article/e14ffa0e864047f48b2cfb9893fbd01f
Autor:
Briac Guibourg, Jean-Luc Grippari, Virginie Conan-Charlet, Glen Le Flahec, Pascale Marcorelles, Emma Cloarec, Arnaud Uguen, Isabelle Quintin-Roué
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 28:719-724
Patients with NTRK-rearranged tumors can be now treated using anti-TRK-targeted therapies making NTRK testing important for treatment choices in patients with advanced cancers. Pan-TRK immunohistochemistry (IHC) could be a valuable premolecular scree
Autor:
Manon Briolais, Gilles Lemasson, Pascale Marcorelles, Briac Guibourg, Françoise Ledé, Jean-Luc Grippari, Glen Le Flahec, Arnaud Uguen
Publikováno v:
Journal of Clinical Pathology. 73:116-119
Beyond targeted therapy for patients with BRAF-mutated melanomas and immunotherapy in patients lacking BRAF mutations, anti-MEK therapy has been proposed in patients with advanced melanomas harbouring BRAF fusions. BRAF fusions diagnosis in patients
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 27:565-571
ALK inhibitors have improved the therapeutic management of patients with ALK-rearranged advanced non-small cell lung cancers (NSCLC). Several diagnostic methods, mainly fluorescent in situ hybridization (FISH) and immunohistochemistry (IHC), can be u
Autor:
Arnaud Uguen, Pascale Marcorelles, Briac Guibourg, Bogdan Badic, Jean-Pierre Bail, Glen Le Flahec, Laurent Doucet, Ulrike Schick
Publikováno v:
Human Pathology. 72:135-143
Mismatch repair-deficient (dMMR) colorectal cancers (CRCs) are good responders to anti-programmed cell death ligand-1 (PD-L1) immunotherapy, but the value of PD-L1 testing remains unclear. We studied PD-L1 expression and the tumor immune microenviron
Autor:
Laurent Misery, Emilie Brenaut, Glen Le Flahec, Marine Sevray, Alexandra Trimaille, Pierre-François Dupré
Publikováno v:
JAAD Case Reports
Hidradenitis suppurativa (HS) is a chronic and inflammatory skin follicular disease in the apocrine gland–bearing areas of the body. It is characterized by recurrent painful nodules, cysts, and abscesses that can rupture and lead to the formation o
Autor:
Arnaud Uguen, Virginie Conan-Charlet, Annabelle Remoué, Laetitia Lambros, Pascale Marcorelles, Amélie Bourhis, Glen Le Flahec
Publikováno v:
Pathology International. 69:94-96
Anti-TRK targeted therapies offer opportunities to treat patients with advanced NTRK1/2/3-rearranged cancers. Beyond NTRK-rearranged secretory breast carcinomas, little is known about NTRK rearrangements and the expression of TRK proteins in non-secr
Autor:
Laetitia Lambros, Annabelle Remoué, Arnaud Uguen, Pascale Marcorelles, Isabelle Quintin-Roué, Glen Le Flahec, Amélie Bourhis
Publikováno v:
Applied immunohistochemistrymolecular morphology : AIMM. 28(6)
Biomarker analyses have become mandatory for treatment choices in patients with advanced non-small cell lung cancers. PD-L1 expression for immunotherapy as well as oncogenic molecular alterations for targeted therapies must be analyzed in tumor sampl