Zobrazeno 1 - 10
of 1 338
pro vyhledávání: '"Glen, Kristiansen"'
Autor:
Marit Bernhardt, Christine Sanders, Oliver Hommerding, Dora Nagy, Tobias Kreft, Xiaolin Zhou, Glen Kristiansen
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background The shortage of pathologists in Germany, coupled with an aging workforce, requires innovative approaches to attract medical students to the field. Medical education must address different learning styles to ensure that all student
Externí odkaz:
https://doaj.org/article/5335019f73034bb3ba9a66940fe34591
Autor:
Philipp Krausewitz, Thomas Büttner, Marthe von Danwitz, Richard Weiten, Alexander Cox, Niklas Klümper, Johannes Stein, Julian Luetkens, Glen Kristiansen, Manuel Ritter, Jörg Ellinger
Publikováno v:
BMC Urology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Objective Utilizing personalized risk assessment for clinically significant prostate cancer (csPCa) incorporating multiparametric magnetic resonance imaging (mpMRI) reduces biopsies and overdiagnosis. We validated both multi- and univariate
Externí odkaz:
https://doaj.org/article/4c49d9d626f14075b96bc3d593bd6d71
Autor:
Richard Weiten, Max Niemann, Eduard Below, Lea L. Friker, Damian J. Ralser, Marieta Toma, Glen Kristiansen, Oliver Hahn, Sabrina Zechel, Viktor Grünwald, Tobias Bald, Johannes Siewert, Torsten Pietsch, Manuel Ritter, Michael Hölzel, Markus Eckstein, Abdullah Alajati, Philipp Krausewitz, Niklas Klümper
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Purpose Improved survival rates have been observed in castration‐resistant prostate cancer (CRPC) due to advancements in treatment options. However, individuals with brain metastases still have limited therapeutic options and an unfavorabl
Externí odkaz:
https://doaj.org/article/296319f737d046debd441f74e94d7c29
Autor:
Saif-Eldin Abedellatif, Racha Hosni, Andreas Waha, Gerrit H. Gielen, Mohammed Banat, Motaz Hamed, Erdem Güresir, Anne Fröhlich, Judith Sirokay, Anna-Lena Wulf, Glen Kristiansen, Torsten Pietsch, Hartmut Vatter, Michael Hölzel, Matthias Schneider, Marieta Ioana Toma
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1042 (2024)
Background and aims: Brain metastases are prevalent in the late stages of malignant melanoma. Multimodal therapy remains challenging. Patient-derived organoids (PDOs) represent a valuable pre-clinical model, faithfully recapitulating key aspects of t
Externí odkaz:
https://doaj.org/article/2d511cd06e74457096edb876a891c881
Autor:
Friederike Hoffmann, Alina Franzen, Luka de Vos, Lennert Wuest, Zsófi Kulcsár, Simon Fietz, Alexander Philippe Maas, Sarah Hollick, Marie Yatou Diop, Jennis Gabrielpillai, Timo Vogt, Pia Kuster, Romina Zarbl, Joern Dietrich, Glen Kristiansen, Peter Brossart, Jennifer Landsberg, Sebastian Strieth, Dimo Dietrich
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background The majority of patients with recurrent or metastasized head and neck squamous cell carcinoma (HNSCC) do not benefit from immune checkpoint blockade (ICB) while several patients experience severe and persistent immune-mediated sid
Externí odkaz:
https://doaj.org/article/2828807dfb384e6996689ecfb93a477e
Autor:
Damian J. Ralser, Emmanuelle Herr, Luka de Vos, Zsófi Kulcsár, Romina Zarbl, Niklas Klümper, Gerrit H. Gielen, Alexander Philippe Maas, Friederike Hoffmann, Jörn Dietrich, Pia Kuster, Alexander Mustea, Nicole Glodde, Glen Kristiansen, Sebastian Strieth, Jennifer Landsberg, Dimo Dietrich
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Background Inducible T cell costimulator ICOS is an emerging target in immuno-oncology. The aim of this study was to investigate the epigenetic regulation of ICOS in melanoma by DNA methylation. Methods We comprehensively investigate ICOS DN
Externí odkaz:
https://doaj.org/article/e3bb36e51ff44e6f9b8d700fc99a8755
Autor:
Laura Tascón Padrón, Eva K. Egger, Damian Johannes Ralser, Lucia Otten, Özer-Altan Toksöz, Glen Kristiansen, Walter Stummer, Alexander Mustea
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionComplete macroscopic cytoreduction represents the most important prognostic parameter for overall survival in ovarian cancer. This dogma remains tenacious despite significant improvements in adjuvant systemic treatment. Hence, optimizatio
Externí odkaz:
https://doaj.org/article/d9a80b722b7542c3b6e33f10c836fa70
Autor:
Mostafa A. Aboouf, Julia Armbruster, Franco Guscetti, Markus Thiersch, Andreas Boss, Axel Gödecke, Sandra Winning, Claudia Padberg, Joachim Fandrey, Glen Kristiansen, Anne Bicker, Thomas Hankeln, Max Gassmann, Thomas A. Gorr
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Myoglobin (MB) is expressed in different cancer types and may act as a tumor suppressor in breast cancer. The mechanisms by which basal MB expression level impacts murine mammary tumorigenesis are unclear. We investigated how MB expression i
Externí odkaz:
https://doaj.org/article/2ea2274e1f1e419e9d74aaf7e0ba4faa
Autor:
Miriam Saponaro, Sina Flottmann, Markus Eckstein, Oliver Hommerding, Niklas Klümper, Dillon Corvino, Sana Hosni, Anja Schmidt, Nicolas Mönig, Doris Schmidt, Jörg Ellinger, Marieta Toma, Glen Kristiansen, Tobias Bald, Andrea Alimonti, Manuel Ritter, Michael Hölzel, Abdullah Alajati
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract The prognosis of patients with advanced urothelial carcinoma (UC) remains poor and improving treatment continues to be a major medical need. CUB domain containing protein 1 (CDCP1) is a known oncogene in various types of solid cancers and it
Externí odkaz:
https://doaj.org/article/28d2e8dda3f84273ac26a0b671726370
Autor:
Mateja Condic, Thore Thiesler, Christian Staerk, Niklas Klümper, Jörg Ellinger, Eva K. Egger, Kirsten Kübler, Glen Kristiansen, Alexander Mustea, Damian J. Ralser
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Vulvar squamous cell carcinoma (VSCC) is an uncommon gynecologic malignancy but with an increasing incidence in recent years. Etiologically, VSCC is classified into two subtypes: HPV-dependent and HPV-independent. Localized VSCC i
Externí odkaz:
https://doaj.org/article/57fe9adfda1943c699a45879061aa79b