Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Glen, Hughes"'
Autor:
Annika Åstrand, Cecilia Wingren, Claire Walton, Johan Mattsson, Komal Agrawal, Madelene Lindqvist, Lina Odqvist, Björn Burmeister, Steven Eck, Glen Hughes, Gabriela Luporini Saraiva, Anna Schantz, Ioannis Psallidas, Christopher McCrae
Publikováno v:
PLoS ONE, Vol 19, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/f5cad6e900424cb396d36459f878b7bc
Autor:
Bert Rutten, Simon Young, Magdalena Rhedin, Marita Olsson, Nisha Kurian, Farhat Syed, Augusta Beech, Mark Fidock, Paul Newbold, Dave Singh, Adam Platt, Glen Hughes
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246627 (2021)
There is a growing body of evidence for the utility of eosinophil-derived neurotoxin (EDN) as a biomarker in asthma, including association with eosinophilic airway inflammation, assessment of disease severity and potential for predicting pathogenic r
Externí odkaz:
https://doaj.org/article/327edafbbb0740068136a1cce0d13511
Autor:
Stéphanie Fabre, Pierre Clerson, Jean-Marie Launay, Jean-François Gautier, Tiphaine Vidal-Trecan, Jean-Pierre Riveline, Adam Platt, Anna Abrahamsson, Jeffrey N. Miner, Glen Hughes, Pascal Richette, Thomas Bardin
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Abstract Background The uric acid (UA) level in patients with gout is a key factor in disease management and is typically measured in the laboratory using plasma samples obtained after venous puncture. This study aimed to assess the reliability of im
Externí odkaz:
https://doaj.org/article/65453793918441df89947ddab41763a4
Autor:
Kevin Randall, Neil Henderson, Jaimini Reens, Sonia Eckersley, Ann-Christin Nyström, Marie C South, Clare A Balendran, Gerhard Böttcher, Glen Hughes, Sally A Price
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162076 (2016)
Ulcerative colitis is a chronic inflammatory disease affecting the colon and is characterized by epithelial damage and barrier dysfunction. Upregulation of the tight junction protein claudin-2 by cytokines is hypothesized to contribute to the dysregu
Externí odkaz:
https://doaj.org/article/80c17657d66a47ec82ee182e61c58415
Autor:
Simon Young, Farhat Syed, Bert Rutten, Mark Fidock, Augusta Beech, Marita Olsson, Glen Hughes, Nisha Kurian, Magdalena Rhedin, Dave Singh, Adam Platt, Paul Newbold
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 2, p e0246627 (2021)
PLoS ONE, Vol 16, Iss 2, p e0246627 (2021)
There is a growing body of evidence for the utility of eosinophil-derived neurotoxin (EDN) as a biomarker in asthma, including association with eosinophilic airway inflammation, assessment of disease severity and potential for predicting pathogenic r
Autor:
Simon Young, Rick Davies, Bert Rutten, Dave Singh, Sarah Aldridge, Glen Hughes, Mark Fidock, Adam Platt, Paul Newbold
Publikováno v:
Journal of Immunological Methods. 500:113181
Eosinophil-derived neurotoxin (EDN) is a surrogate biomarker of eosinophil activation and has considerable potential as a precision medicine biomarker in diseases where eosinophils may play a causative role. Clinical data for EDN have been generated
Autor:
Kyoko Matsuguma, Susanna Eketjäll, Tatsuya Yoshihara, Fumihiko Azuma, Glen Hughes, Kei Sakamoto, Alan R. Kugler, Robert C. Alexander, Naoki Uchida, Muir Russell, Samantha Budd Haeberlein, Shunji Matsuki
Publikováno v:
The Journal of Clinical Pharmacology. 57:1460-1471
Lanabecestat (AZD3293; LY3314814) is an orally active potent inhibitor of human β-secretase 1 in clinical development for the treatment of Alzheimer disease. In this first Japanese clinical study for an Alzheimer disease intervention to include cere
Publikováno v:
Handbook of Biomarkers and Precision Medicine ISBN: 9780429202872
Handbook of Biomarkers and Precision Medicine
Handbook of Biomarkers and Precision Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca0367d3e9ff5eb3346dcb44c54bff09
https://doi.org/10.1201/9780429202872-24
https://doi.org/10.1201/9780429202872-24
Publikováno v:
Allergy and immunology.
Introduction: Released from eosinophils, EDN is a biomarker of eosinophilia and eosinophil activation. EDN has potential clinical utility in identifying asthma and COPD patients with an eosinophilic phenotype who may benefit from anti-eosinophilic tr
Autor:
Jean-Pierre Riveline, Jean-François Gautier, Anna Abrahamsson, Tiphaine Vidal-Trecan, Adam Platt, Jean-Marie Launay, Pierre Clerson, Jeffrey N. Miner, Thomas Bardin, Glen Hughes, Stéphanie Fabre, Pascal Richette
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Background The uric acid (UA) level in patients with gout is a key factor in disease management and is typically measured in the laboratory using plasma samples obtained after venous puncture. This study aimed to assess the reliability of immediate U