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pro vyhledávání: '"Gleevec Study Team"'
Autor:
Eva Tsalikian, Andrea Mari, Jeffrey A. Bluestone, Srinath Sanda, Peter A. Gottlieb, Steven M. Willi, Philip Raskin, S. Alice Long, Ele Ferrannini, Noha Lim, Jason L. Gaglia, John M. Wentworth, Linda A. DiMeglio, Jeffrey P. Krischer, Gleevec Study Team, Eric I. Felner, Stephen E. Gitelman, Raghavendra G. Mirmira, J Lori Blanchfield, Brian N. Bundy
Publikováno v:
SSRN Electronic Journal.
Background: Type 1 diabetes results from autoimmune-mediated destruction of beta cells. The tyrosine kinase inhibitor imatinib may impact relevant immunologic and metabolic pathways, and preclinical studies show that it reverses and prevents diabetes