Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Glaucio Monteiro Ferreira"'
Autor:
Glaucio Monteiro Ferreira, Thanigaimalai Pillaiyar, Mario Hiroyuki Hirata, Antti Poso, Thales Kronenberger
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract SARS-CoV-2’s papain-like protease (PLpro) interaction with ligands has recently been explored with a myriad of crystal structures. We used molecular dynamics (MD) simulations to study different PLpro-ligand complexes, their ligand-induced
Externí odkaz:
https://doaj.org/article/dfe3ab47bcb4485094a466b0939f4073
Autor:
Erick Tavares Marcelino Alves, Filipe Gomes Pernichelle, Lucas Adriano Nascimento, Glaucio Monteiro Ferreira, Elizabeth Igne Ferreira
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 1028 (2023)
Neglected diseases, primarily found in tropical regions of the world, present a significant challenge for impoverished populations. Currently, there are 20 diseases considered neglected, which greatly impact the health of affected populations and res
Externí odkaz:
https://doaj.org/article/ec9e2b5ae60d4052bd91b8e12d49fc80
Autor:
Glaucio Monteiro Ferreira, Thales Kronenberger, Vinicius Gonçalves Maltarollo, Antti Poso, Fernando de Moura Gatti, Vitor Medeiros Almeida, Sandro Roberto Marana, Carla Duque Lopes, Daiane Yukie Tezuka, Sérgio de Albuquerque, Flavio da Silva Emery, Gustavo Henrique Goulart Trossini
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 428 (2023)
Trypanosoma cruzi, the etiological agent of Chagas disease, relies on finely coordinated epigenetic regulation during the transition between hosts. Herein we targeted the silent information regulator 2 (Sir2) enzyme, a NAD+-dependent class III histon
Externí odkaz:
https://doaj.org/article/1982c52c73ab40ffae0e62189ec84db7
Autor:
André Rinaldi Fukushima, Juliana Weckx Peña-Muñoz, Luís Antônio Baffile Leoni, Maria Aparecida Nicoletti, Glaucio Monteiro Ferreira, Jan Carlo Morais Oliveira Bertassoni Delorenzi, Esther Lopes Ricci, Marlos Eduardo Brandão, Lorena de Paula Pantaleon, Vagner Gonçalves-Junior, Paula Andrea Faria Waziry, Paulo Cesar Maiorka, Helenice de Souza Spinosa
Publikováno v:
Toxics, Vol 10, Iss 5, p 269 (2022)
Anticholinesterase pesticides are a main cause of the intentional or accidental poisoning of animals. Anticholinesterases include several substances that cause the overstimulation of both central and peripheral acetylcholine-dependent neurotransmissi
Externí odkaz:
https://doaj.org/article/ed2227e5520a4127b3d377434542fc7a
Autor:
Carolina Dagli-Hernandez, Jéssica Bassani Borges, Elisangela da Silva Rodrigues Marçal, Renata Caroline Costa de Freitas, Augusto Akira Mori, Rodrigo Marques Gonçalves, Andre Arpad Faludi, Victor Fernandes de Oliveira, Glaucio Monteiro Ferreira, Gisele Medeiros Bastos, Yitian Zhou, Volker M. Lauschke, Alvaro Cerda, Mario Hiroyuki Hirata, Rosario Dominguez Crespo Hirata
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 944 (2022)
Statins are the first-line treatment for familial hypercholesterolemia (FH), but response is highly variable due to genetic and nongenetic factors. Here, we explored the association between response and genetic variability in 114 Brazilian adult FH p
Externí odkaz:
https://doaj.org/article/ea95afb671784795ae2502ff288ed59a
Autor:
Renan Fernandes Espírito-Santo, Cassio Santana Meira, Rafael Dos Santos Costa, Otávio Passos Souza Filho, Afranio Ferreira Evangelista, Gustavo Henrique Goulart Trossini, Glaucio Monteiro Ferreira, Eudes da Silva Velozo, Cristiane Flora Villarreal, Milena Botelho Pereira Soares
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179174 (2017)
Braylin belongs to the group of natural coumarins, a group of compounds with a wide range of pharmacological properties. Here we characterized the pharmacological properties of braylin in vitro, in silico and in vivo in models of inflammatory/immune
Externí odkaz:
https://doaj.org/article/b6bec796c1d7470084a0b7c6447b0980
Publikováno v:
Molecules, Vol 22, Iss 12, p 1884 (2017)
Cyanobacteria are able to produce a wide range of secondary metabolites, including toxins and protease inhibitors, with diverse biological activities. Microginins are small linear peptides biosynthesized by cyanobacteria species that act against prot
Externí odkaz:
https://doaj.org/article/3aad23d95349493b834c213ccd784333
Autor:
Glaucio Monteiro Ferreira
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
A doença de Chagas, causada pelo parasita Trypanosoma cruzi, acomete entre 6 a 8 milhões de pessoas em todo o mundo. Conhecida como tripanossomíase americana, por ter sido considerada endêmica apenas na América Latina, esta doença, se espalhou
Autor:
Vitor Galvão Lopes, Victor Fernandes de Oliveira, Livia Mendonça Munhoz Dati, Michel Satya Naslavsky, Glaucio Monteiro Ferreira, Mario Hiroyuki Hirata
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-9
The Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) promotes the degradation of the low-density lipoprotein receptors (LDLR). Gain-of-function (GOF) variants of PCSK9 significantly affects lipid metabolism leading to coronary artery disease (CA
These are all the trajectories used to study CRD4 conformational stability under normal (pH = 7) and acid (pH = 5) environments, as well as in complex with the auxiliary Ca II, a-mannose and a-mannose-1,2-a-mannose.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec84e39d2301932e64fa38d461a41398