Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration.

Autor: Kretschmer V; Faculty of Biology, Institute of Molecular Physiology, Johannes Gutenberg-University, Mainz, Germany., Schneider S; Faculty of Biology, Institute of Molecular Physiology, Johannes Gutenberg-University, Mainz, Germany., Matthiessen PA; Faculty of Biology, Institute of Molecular Physiology, Johannes Gutenberg-University, Mainz, Germany., Reichert D; Faculty of Biology, Institute of Molecular Physiology, Johannes Gutenberg-University, Mainz, Germany.; National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America., Hotaling N; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America., Glasßer G; Max Planck Institute for Polymer Research, Mainz, Germany., Lieberwirth I; Max Planck Institute for Polymer Research, Mainz, Germany., Bharti K; National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America., De Cegli R; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy., Conte I; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.; University of Naples 'Federico II', Naples, Italy., Nandrot EF; Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France., May-Simera HL; Faculty of Biology, Institute of Molecular Physiology, Johannes Gutenberg-University, Mainz, Germany.

Publikováno v: PLoS biology [PLoS Biol] 2023 Dec 04; Vol. 21 (12), pp. e3002402. Date of Electronic Publication: 2023 Dec 04 (Print Publication: 2023).