Significant Loop Motions in the SsoPTP Protein Tyrosine Phosphatase Allow for Dual General Acid Functionality.

Autor: Pinkston J; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300, United States., Jo J; Department of Chemistry, Yale University, 225 Prospect Street, New Haven, Connecticut 06520, United States., Olsen KJ; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300, United States., Comer D; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300, United States., Glaittli CA; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300, United States., Loria JP; Department of Chemistry, Yale University, 225 Prospect Street, New Haven, Connecticut 06520, United States.; Department of Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, Connecticut 06520, United States., Johnson SJ; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300, United States., Hengge AC; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300, United States.

Publikováno v: Biochemistry [Biochemistry] 2021 Sep 28; Vol. 60 (38), pp. 2888-2901. Date of Electronic Publication: 2021 Sep 08.