Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Gladys Y. P. Ko"'
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Peptide Lv is a small endogenous secretory peptide that is expressed in various tissues and conserved across different species. Patients with diabetic retinopathy, an ocular disease with pathological angiogenesis, have upregulated peptide Lv in their
Externí odkaz:
https://doaj.org/article/1598e21caed249f2a2c1ddcc584ca16c
Autor:
Dylan L. Pham, Autumn Niemi, Ria Blank, Gabriella Lomenzo, Jenivi Tham, Michael L. Ko, Gladys Y.-P. Ko
Publikováno v:
Cells, Vol 12, Iss 12, p 1651 (2023)
Peptide Lv is a small endogenous secretory peptide that is proangiogenic through hyperpolarizing vascular endothelial cells (ECs) by enhancing the current densities of KCa3.1 channels. However, it is unclear how peptide Lv enhances these currents. On
Externí odkaz:
https://doaj.org/article/4970a53619fc4e83a56f369e22270d6b
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12099 (2022)
Diabetic retinopathy (DR) is a chronic disease associated with diabetes mellitus and is a leading cause of visual impairment among the working population in the US. Clinically, DR has been diagnosed and treated as a vascular complication, but it adve
Externí odkaz:
https://doaj.org/article/6c0410d2f306497f8c98f0a9ed59ba1a
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
Introduction Diabetic retinopathy (DR) is the leading cause of blindness among the working population in the USA. Current therapies, including anti-vascular endothelial growth factor treatments, cannot completely reverse the visual defects induced by
Externí odkaz:
https://doaj.org/article/01b0fee84bf44b67b5e96651424d2237
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1135 (2021)
Diabetic retinopathy (DR) is a chronic complication associated with diabetes and the number one cause of blindness in working adults in the US. More than 90% of diabetic patients have obesity-associated type 2 diabetes (T2D), and 60% of T2D patients
Externí odkaz:
https://doaj.org/article/a0add589b91d425e970bbb97bdee9483
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
Mitochondrial fission and fusion are dependent on cellular nutritional states, and maintaining this dynamics is critical for the health of cells. Starvation triggers mitochondrial fusion to maintain bioenergetic efficiency, but during nutrient overlo
Externí odkaz:
https://doaj.org/article/51a5204a009a4c5da27b2ded0cc38f8c
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
L-type voltage-gated calcium channels (LTCCs) regulate tonic neurotransmitter release from sensory neurons including retinal photoreceptors. There are three types of LTCCs (Cav1.2, Cav1.3, and Cav1.4) expressed in the retina. While Cav1.2 is expresse
Externí odkaz:
https://doaj.org/article/bd40e214238e4657b65233465e8441db
Publikováno v:
Journal of Cellular and Molecular Medicine
Obesity‐associated type 2 diabetes (T2D) is on the rise in the United States due to the obesity epidemic, and 60% of T2D patients develop diabetic retinopathy (DR) in their lifetime. Chronic inflammation is a hallmark of obesity and T2D and a well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d315fe70226d723e4fd20b2cba23fe4
https://doi.org/10.1111/jcmm.17012
https://doi.org/10.1111/jcmm.17012
Autor:
Preethi H. Gunaratne, Brandon Mistretta, Robert J. Schwartz, Suchi Raghunathan, Bradley K. McConnell, Liheng Shi, Dinakar Iyer, Jose Francisco Islas, Gladys Y.-P. Ko
Publikováno v:
J Mol Cell Cardiol
We used a screening strategy to test for reprogramming factors for the conversion of human cardiac progenitor cells (CPCs) into Pacemaker-like cells. Human transcription factors SHOX2, TBX3, TBX5, TBX18, and the channel protein HCN2, were transiently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cefeb8ed2e5add94803c1112f77e3b
https://doi.org/10.1016/j.yjmcc.2019.09.015
https://doi.org/10.1016/j.yjmcc.2019.09.015
Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 1135, p 1135 (2021)
Volume 9
Issue 9
Biomedicines, Vol 9, Iss 1135, p 1135 (2021)
Volume 9
Issue 9
Diabetic retinopathy (DR) is a chronic complication associated with diabetes and the number one cause of blindness in working adults in the US. More than 90% of diabetic patients have obesity-associated type 2 diabetes (T2D), and 60% of T2D patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe38420de938d50913b554ee25c61f98
https://pubmed.ncbi.nlm.nih.gov/34572320
https://pubmed.ncbi.nlm.nih.gov/34572320