Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Gladys Y.‐P. Ko"'
Autor:
Dylan L. Pham, Autumn Niemi, Ria Blank, Gabriella Lomenzo, Jenivi Tham, Michael L. Ko, Gladys Y.-P. Ko
Publikováno v:
Cells, Vol 12, Iss 12, p 1651 (2023)
Peptide Lv is a small endogenous secretory peptide that is proangiogenic through hyperpolarizing vascular endothelial cells (ECs) by enhancing the current densities of KCa3.1 channels. However, it is unclear how peptide Lv enhances these currents. On
Externí odkaz:
https://doaj.org/article/4970a53619fc4e83a56f369e22270d6b
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12099 (2022)
Diabetic retinopathy (DR) is a chronic disease associated with diabetes mellitus and is a leading cause of visual impairment among the working population in the US. Clinically, DR has been diagnosed and treated as a vascular complication, but it adve
Externí odkaz:
https://doaj.org/article/6c0410d2f306497f8c98f0a9ed59ba1a
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1135 (2021)
Diabetic retinopathy (DR) is a chronic complication associated with diabetes and the number one cause of blindness in working adults in the US. More than 90% of diabetic patients have obesity-associated type 2 diabetes (T2D), and 60% of T2D patients
Externí odkaz:
https://doaj.org/article/a0add589b91d425e970bbb97bdee9483
Autor:
Liheng Shi, Min Zhao, Colette A. Abbey, Shu‐Huai Tsai, Wankun Xie, Dylan Pham, Samantha Chapman, Kayla J. Bayless, Travis W. Hein, Robert H. Rosa, Michael L. Ko, Lih Kuo, Gladys Y.‐P. Ko
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 22 (2019)
Background We recently discovered a small endogenous peptide, peptide Lv, with the ability to activate vascular endothelial growth factor receptor 2 and its downstream signaling. As vascular endothelial growth factor through vascular endothelial grow
Externí odkaz:
https://doaj.org/article/ade4de909b684a7ca1ef14f75a5a3b5e
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
Mitochondrial fission and fusion are dependent on cellular nutritional states, and maintaining this dynamics is critical for the health of cells. Starvation triggers mitochondrial fusion to maintain bioenergetic efficiency, but during nutrient overlo
Externí odkaz:
https://doaj.org/article/51a5204a009a4c5da27b2ded0cc38f8c
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
L-type voltage-gated calcium channels (LTCCs) regulate tonic neurotransmitter release from sensory neurons including retinal photoreceptors. There are three types of LTCCs (Cav1.2, Cav1.3, and Cav1.4) expressed in the retina. While Cav1.2 is expresse
Externí odkaz:
https://doaj.org/article/bd40e214238e4657b65233465e8441db
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Modulation of ion channels by extracellular proteins plays critical roles in shaping synaptic plasticity. Retinoschisin (RS1) is an extracellular adhesive protein secreted from photoreceptors and bipolar cells, and it plays an important role during r
Externí odkaz:
https://doaj.org/article/dd25c298b4c74b79a81a46098d300f99
Autor:
Liheng Shi, Michael L. Ko, Cathy Chia-Yu Huang, So-Young Park, Min-Pyo Hong, Chaodong Wu, Gladys Y.-P. Ko
Publikováno v:
Journal of Diabetes Research, Vol 2014 (2014)
Externí odkaz:
https://doaj.org/article/4b8702a666f442a39dd3f9e193d2cd46
Publikováno v:
Journal of Cellular and Molecular Medicine
Obesity‐associated type 2 diabetes (T2D) is on the rise in the United States due to the obesity epidemic, and 60% of T2D patients develop diabetic retinopathy (DR) in their lifetime. Chronic inflammation is a hallmark of obesity and T2D and a well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d315fe70226d723e4fd20b2cba23fe4
https://doi.org/10.1111/jcmm.17012
https://doi.org/10.1111/jcmm.17012
Autor:
Preethi H. Gunaratne, Brandon Mistretta, Robert J. Schwartz, Suchi Raghunathan, Bradley K. McConnell, Liheng Shi, Dinakar Iyer, Jose Francisco Islas, Gladys Y.-P. Ko
Publikováno v:
J Mol Cell Cardiol
We used a screening strategy to test for reprogramming factors for the conversion of human cardiac progenitor cells (CPCs) into Pacemaker-like cells. Human transcription factors SHOX2, TBX3, TBX5, TBX18, and the channel protein HCN2, were transiently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cefeb8ed2e5add94803c1112f77e3b
https://doi.org/10.1016/j.yjmcc.2019.09.015
https://doi.org/10.1016/j.yjmcc.2019.09.015