Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gladys W. Wong"'
Autor:
Mahmood Mohtashami, Juan Carlos Zúñiga-Pflücker, Edward L. Y. Chen, David L. Wiest, Gladys W. Wong, Michele K. Anderson, Jastaranpreet Singh, Tracy Sh In, Payam Zarin
Publikováno v:
Immunology and Cell Biology
γδ T‐cells perform a wide range of tissue‐ and disease‐specific functions that are dependent on the effector cytokines produced by these cells. However, the aggregate signals required for the development of interferon‐γ (IFNγ) and interle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2afaf44bf11fcdcc352c61c6bdf16d7
http://europepmc.org/articles/PMC6197911
http://europepmc.org/articles/PMC6197911
Autor:
Jens-Peter Holst Lauritsen, David L. Wiest, Michelle L. Joachims, Francis Coffey, Juan Carlos Zúñiga-Pflücker, Terkild B. Buus, Sang-Yun Lee, Linda F. Thompson, Gladys W. Wong, Dietmar J. Kappes
Publikováno v:
The Journal of Experimental Medicine
CD73 expression is induced in response to TCR ligation and identifies a population of thymocytes that are committed to the γδ T cell fate.
Numerous studies indicate that γδ T cell receptor (γδTCR) expression alone does not reliably mark co
Numerous studies indicate that γδ T cell receptor (γδTCR) expression alone does not reliably mark co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92dc3e9083add9afc5a79268ab5ff8bb
https://doi.org/10.1084/jem.20131540
https://doi.org/10.1084/jem.20131540
Publikováno v:
Seminars in Immunology. 22:228-236
A common bipotent thymocyte precursor gives rise to both lineages of T cells, αβ and γδ. However, the cell intrinsic and extrinsic factors that influence αβ- versus γδ-lineage bifurcation remain controversial. γδ T cells play a unique and v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64eebe026afff3418e93f67917cbc3a4
https://doi.org/10.1016/j.smim.2010.04.005
https://doi.org/10.1016/j.smim.2010.04.005
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(15)
Developing thymocytes bifurcate from a bipotent precursor into αβ- or γδ-lineage T cells. Considering this common origin and the fact that the T-cell receptor (TCR) β-, γ-, and δ-chains simultaneously rearrange at the double negative (DN) stag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6423f2b300b5d8327213e2c0e2313a4
https://pubmed.ncbi.nlm.nih.gov/24706811
https://pubmed.ncbi.nlm.nih.gov/24706811
Publikováno v:
Blood. 120(7)
The developmental progression of immature thymocytes requires cooperative input from several pathways, with Notch signals playing an indispensable role at the T-cell receptor (TCR)–β selection checkpoint. Notch signals affect the activation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41583f99d2d01956774d4892b7a22955
https://pubmed.ncbi.nlm.nih.gov/22899471
https://pubmed.ncbi.nlm.nih.gov/22899471
Publikováno v:
Seminars in immunology. 22(4)
A common bipotent thymocyte precursor gives rise to both lineages of T cells, alphabeta and gammadelta. However, the cell intrinsic and extrinsic factors that influence alphabeta- versus gammadelta-lineage bifurcation remain controversial. gammadelta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4226eb26c2d679321b471b1db248bb19
https://pubmed.ncbi.nlm.nih.gov/20466561
https://pubmed.ncbi.nlm.nih.gov/20466561
Autor:
Michele Rhodes, Juliette M. Lefebvre, David L. Wiest, Gladys W. Wong, Juan Carlos Zúñiga-Pflücker, Jens Peter Holst Lauritsen, Maria Ciofani, Sang-Yun Lee, Dietmar J. Kappes
Publikováno v:
Immunity. (4):565-575
alphabeta and gammadelta T cells arise from a common thymocyte progenitor during development in the thymus. Emerging evidence suggests that the pre-T cell receptor (pre-TCR) and gammadelta T cell receptor (gammadeltaTCR) play instructional roles in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95d873ea6566cc31c8565fa8ff2c32d