Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Gladys, Ouedraogo"'
Autor:
Lizao, Chen, Fang, Huang, CaiChun, Kei, Jinsong, Zhang, Jing, Sang, Ying, Yang, Rong, Kuang, Xikun, Xiong, Qing, Li, Yanfeng, Liu, Qin, Qin, E, Zhao, Nathalie, Alépée, Gladys, Ouedraogo, Nan, Li, Zhenzi, Cai
Publikováno v:
Mutagenesis. 37:173-181
A novel in vitro 3D micronucleus assay was developed in China using the EpiSkin™ 3D human skin model. This EpiSkin™ Micronucleus Assay showed good predictivity and reproducibility during internal validation and is expected to contribute to in vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a2e860d8e43064c453ac45444e3c85
https://doi.org/10.1093/mutage/geac014
https://doi.org/10.1093/mutage/geac014
Autor:
Véronique Thybaud, Kerry L. Dearfield, Roland Froetschl, Jennifer C. Sasaki, Mirjam Luijten, George E. Johnson, John Nicolette, Michelle R. Embry, Laura Custer, Gladys Ouedraogo, Raja S. Settivari
Publikováno v:
Environmental and Molecular Mutagenesis. 62:512-525
We present a hypothetical case study to examine the use of a next-generation framework developed by the Genetic Toxicology Technical Committee of the Health and Environmental Sciences Institute for assessing the potential risk of genetic damage from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94a80d1984a7afa084ed6b9f60639c4
https://doi.org/10.1002/em.22467
https://doi.org/10.1002/em.22467
Autor:
Chihae Yang, James F Rathman, Bruno Bienfait, Matthew Burbank, Ann Detroyer, Steven J. Enoch, James W. Firman, Steve Gutsell, Nicola J. Hewitt, Bryan Hobocienski, Gerry Kenna, Judith C. Madden, Tomasz Magdziarz, Jörg Marusczyk, Aleksandra Mostrag-Szlichtyng, Christopher-Tilman Krueger, Cathy Lester, Catherine Mahoney, Abdulkarim Najjar, Gladys Ouedraogo, Katarzyna R. Przybylak, J. Vinicius Ribeiro, Mark T.D. Cronin
Publikováno v:
Computational Toxicology. 26:100272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5741cc1baeed6bd50fa239de98753095
https://doi.org/10.1016/j.comtox.2023.100272
https://doi.org/10.1016/j.comtox.2023.100272
Autor:
Stefan Pfuhler, Thomas R Downs, Nicola J Hewitt, Sebastian Hoffmann, Greg C Mun, Gladys Ouedraogo, Shambhu Roy, Rodger D Curren, Marilyn J Aardema
Publikováno v:
Mutagenesis
In vitro test batteries have become the standard approach to determine the genotoxic potential of substances of interest across industry sectors. While useful for hazard identification, standard in vitro genotoxicity assays in 2D cell cultures have l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9586d95da3b75af0029071152db535
http://europepmc.org/articles/PMC8081377
http://europepmc.org/articles/PMC8081377
Autor:
Susanne Hougaard Bennekou, Rabea Graepel, Marcel Leist, Annette Bitsch, Gladys Ouedraogo, Jan G. Hengstler, Sylvia Escher, Hennicke Kamp, Derek Knight, Manuel Pastor, Ulf Norinder, Sharon B. Stuard, Matthias Herzler, Andrew White, Ciarán Fisher, Bob van de Water, Dinant Kroese, Barbara Zdrazil
Publikováno v:
Archives of Toxicology, 93(12), 3643-3667
Archives of Toxicology
Archives of Toxicology
Read-across is one of the most frequently used alternative tools for hazard assessment, in particular for complex endpoints such as repeated dose or developmental and reproductive toxicity. Read-across extrapolates the outcome of a specific toxicolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b17071c3e18d74998731b9032313a1
https://doi.org/10.1007/s00204-019-02591-7
https://doi.org/10.1007/s00204-019-02591-7
Publikováno v:
Annual Review of Biomedical Engineering
The liver is the central hub of xenobiotic metabolism and consequently the organ most prone to cosmetic- and drug-induced toxicity. Failure to detect liver toxicity or to assess compound clearance during product development is a major cause of postma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76915d2450abad46f21b921a045f4f5
https://doi.org/10.1146/annurev-bioeng-060418-052305
https://doi.org/10.1146/annurev-bioeng-060418-052305
Autor:
Kerstin Reisinger, R. Fautz, Stefan Pfuhler, Nicola J. Hewitt, Julia Kenny, B.A. Wall, Gladys Ouedraogo, Sebastian Hoffmann
Publikováno v:
Toxicology Letters. 350:S148-S149
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14e6b3c7f115b5f0ab28670c92c358f5
https://doi.org/10.1016/s0378-4274(21)00592-0
https://doi.org/10.1016/s0378-4274(21)00592-0
Autor:
B. Montemayor, R. Taalman, Rajeshwar P. Verma, Hajime Kojima, J. Field, Matt Dent, Vera Rogiers, C. Willett, Janine Ezendam, João Barroso, Gladys Ouedraogo, M. Lorencini, Chihae Yang, Tara S. Barton-Maclaren, Susanne Hougaard Bennekou, Paul L. Carmichael, E. Vaillancourt, Suzanne Fitzpatrick, Reinhard Kreiling, J. Ansell, R. Mazaro-Costa, J. Oliveira, Russell S. Thomas, Kim Boekelheide, D. Smegal, Catherine Mahony, Y. Tokura, M. Hatao
Publikováno v:
Dent, M P, Vaillancourt, E, Thomas, R S, Carmichael, P L, Ouedraogo, G, Kojima, H, Barroso, J, Ansell, J, Barton-Maclaren, T S, Bennekou, S H, Boekelheide, K, Ezendam, J, Field, J, Fitzpatrick, S, Hatao, M, Kreiling, R, Lorencini, M, Mahony, C, Montemayor, B, Mazaro-Costa, R, Oliveira, J, Rogiers, V, Smegal, D, Taalman, R, Tokura, Y, Verma, R, Willett, C & Yang, C 2021, ' Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients ', Regulatory Toxicology and Pharmacology, vol. 125, 105026 . https://doi.org/10.1016/j.yrtph.2021.105026
Next generation risk assessment (NGRA) is an exposure-led, hypothesis-driven approach that has the potential to support animal-free safety decision-making. However, significant effort is needed to develop and test the in vitro and in silico (computat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9c756a1ebd0b3e0cf3dcb968552455
https://pubmed.ncbi.nlm.nih.gov/34389358
https://pubmed.ncbi.nlm.nih.gov/34389358
Autor:
Gladys Ouedraogo, Camilla Alexander-White, Dagmar Bury, Harvey J. Clewell, Mark Cronin, Tom Cull, Matthew Dent, Bertrand Desprez, Ann Detroyer, Corie Ellison, Stefania Giammanco, Eric Hack, Nicola J. Hewitt, Gerry Kenna, Martina Klaric, Reinhard Kreiling, Cathy Lester, Catherine Mahony, Enrico Mombelli, Jorge Naciff, John O'Brien, Andreas Schepky, Sarah Tozer, Bart van der Burg, Barbara van Vugt-Lussenburg, Sharon Stuard, null Cosmetics Europe
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 132
Parabens are esters of para-hydroxybenzoic acid that have been used as preservatives in many types of products for decades including agrochemicals, pharmaceuticals, food and cosmetics. This illustrative case study with propylparaben (PP) demonstrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4309dbeaf4d25867d81982bd4812f818
https://pubmed.ncbi.nlm.nih.gov/35508214
https://pubmed.ncbi.nlm.nih.gov/35508214
Autor:
Bertrand Desprez, Alicia Paini, Nicola J. Hewitt, Catherine Mahony, Mark T. D. Cronin, Cathy Lester, Eric Hack, Gerry Kenna, Andreas Schepky, James W. Firman, Alina Efremenko, Harvey J. Clewell, Martina Klaric, Camilla Alexander-White, Cosmetics Europe, Dagmar Bury, Ann Detroyer, Gladys Ouedraogo
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 123
This case study on the model substance caffeine demonstrates the viability of a 10-step read-across (RAX) framework in practice. New approach methodologies (NAM), including RAX and physiologically-based kinetic (PBK) modelling were used to assess the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563d92294b6d51bc097fb99bbbd42ff6
https://pubmed.ncbi.nlm.nih.gov/33905778
https://pubmed.ncbi.nlm.nih.gov/33905778