Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gladiola Goranci-Buzhala"'
Autor:
Matthias Rübsam, Aaron F. Mertz, Akiharu Kubo, Susanna Marg, Christian Jüngst, Gladiola Goranci-Buzhala, Astrid C. Schauss, Valerie Horsley, Eric R. Dufresne, Markus Moser, Wolfgang Ziegler, Masayuki Amagai, Sara A. Wickström, Carien M. Niessen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
In multi-layered epithelia tight junctions (TJ) are confined to the most suprabasal viable layer. Here the authors show that this is regulated by ubiquitously localized E-cadherin tuning junctional tension and EGFR activity to inhibit TJ formation in
Externí odkaz:
https://doaj.org/article/13725cc72379417abbcc0dbb0fa23102
Autor:
Roberto Pallini, Lucia Ricci-Vitiani, Aruljothi Mariappan, Gladiola Goranci-Buzhala, Jay Gopalakrishnan
Publikováno v:
Cell Death and Differentiation
The human brain organoids derived from pluripotent cells are a new class of three-dimensional tissue systems that recapitulates several neural epithelial aspects. Brain organoids have already helped efficient modeling of crucial elements of brain dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640a4535a648792d67dae2482aa3c79f
https://doi.org/10.1038/s41418-020-00679-7
https://doi.org/10.1038/s41418-020-00679-7
Autor:
Argyris Papantonis, Aruljothi Mariappan, Natasa Josipovic, Roberto Pallini, Lucia Ricci-Vitiani, Simone Pacion, Gladiola Goranci-Buzhala, Marco Gottardo, Giuliano Callaini, Jay Gopalakrishnan, Johannes Ptok, Krishnaraj Rajalingam, Brian David Dynlacht, Kamyar Hadian
Glioblastoma multiforme (GBM) possesses glioma stem cells (GSCs) that promote self-renewal, tumor propagation, and relapse. GBM has a poor prognosis, and currently, there are no curative options exist. Understanding the mechanisms of GSCs self-renewa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fe41353847441d3e39fcdb926bac2d8
https://doi.org/10.1101/2020.12.23.424140
https://doi.org/10.1101/2020.12.23.424140
Autor:
Mariachiara Buccarelli, Gladiola Goranci-Buzhala, Anand Ramani, Elke Gabriel, Quintino Giorgio D'Alessandris, Roberto Pallini, Lucia Ricci-Vitiani, Aruljothi Mariappan, Jay Gopalakrishnan
Publikováno v:
Cell Reports. 31:107738
Glioblastoma (GBM) possesses glioma stem cells (GSCs) that exhibit aggressive invasion behavior in the brain. Current preclinical GBM invasion assays using mouse brain xenografts are time consuming and less efficient. Here, we demonstrate an array of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d71d93d1ce92319170c391784408c5
https://doi.org/10.1016/j.celrep.2020.107738
https://doi.org/10.1016/j.celrep.2020.107738
Publikováno v:
Cancer discovery. 7(12)
Summary: In this issue, Zhao and colleagues demonstrate that loss of primary cilia in medulloblastoma cells confers resistance to the Smoothened (SMO) inhibitor sonidegib. When treated with sonidegib, medulloblastoma cells lost their cilia and gained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0662e726347c162eec6168b995e5909d
https://pubmed.ncbi.nlm.nih.gov/28923910
https://pubmed.ncbi.nlm.nih.gov/28923910
Autor:
Sara A. Wickström, Aaron F. Mertz, Gladiola Goranci-Buzhala, Valerie Horsley, Masayuki Amagai, Eric R. Dufresne, Christian Jüngst, Carien M. Niessen, Susanna Marg, Astrid Schauss, Markus Moser, Wolfgang H. Ziegler, Matthias Rübsam, Akiharu Kubo
Publikováno v:
Nature Communications
Nat Commun
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature Communications, 8
Nat Commun
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature Communications, 8
Generation of a barrier in multi-layered epithelia like the epidermis requires restricted positioning of functional tight junctions (TJ) to the most suprabasal viable layer. This positioning necessitates tissue-level polarization of junctions and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96092b6a20471118ca5608966bd9cc0e
https://hdl.handle.net/11858/00-001M-0000-002E-952D-611858/00-001M-0000-002E-952B-A
https://hdl.handle.net/11858/00-001M-0000-002E-952D-611858/00-001M-0000-002E-952B-A
Autor:
Karthick Natarajan, Anand Ramani, Maria Giovanna Riparbelli, Ulrike Karow, Argyris Papantonis, Oleg Krut, Elke Gabriel, Marco Gottardo, Giuliano Callaini, Li Ming Gooi, Olli Vapalahti, Martin Krönke, Milos Nikolic, Olaf Utermöhlen, Franziska Peters, Jay Gopalakrishnan, Suvi Kuivanen, Jonas Schmidt-Chanasit, Teemu Smura, Essi M. Korhonen, Gladiola Goranci-Buzhala
Publikováno v:
Cell Stem Cell. 20:397-406.e5
The recent Zika virus (ZIKV) epidemic is associated with microcephaly in newborns. Although the connection between ZIKV and neurodevelopmental defects is widely recognized, the underlying mechanisms are poorly understood. Here we show that two recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647eece0df3e592a7a740e07525179cc
https://doi.org/10.1016/j.stem.2016.12.005
https://doi.org/10.1016/j.stem.2016.12.005