Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Glòria Arqué"'
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 2, Pp 312-319 (2009)
Dual-specificity tyrosine-regulated kinase 1A (DYRK1A) is a candidate gene for the Down syndrome neurological defects and may be involved in the progression of Alzheimer's disease. Heterozygous mice for Dyrk1A (Dyrk1A+/−) exhibit decreased brain si
Externí odkaz:
https://doaj.org/article/493c0be50bb64e758d307d8f1f260ef3
Autor:
Glòria Arqué, Vassiliki Fotaki, David Fernández, María Martínez de Lagrán, Maria L Arbonés, Mara Dierssen
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2575 (2008)
BackgroundPathogenic aneuploidies involve the concept of dosage-sensitive genes leading to over- and underexpression phenotypes. Monosomy 21 in human leads to mental retardation and skeletal, immune and respiratory function disturbances. Most of the
Externí odkaz:
https://doaj.org/article/0ebf15927bdb41ad85aa87c511de0217
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Remote ischemic conditioning (RIC) is a promising therapeutic approach for ischemic stroke patients. It has been proven that RIC reduces infarct size and improves functional outcomes. RIC can be applied either before ischemia (pre-conditioni
Externí odkaz:
https://doaj.org/article/c2ea05ce2cc045c5855ec1820ebe0cb0
Autor:
Coral Torres-Querol, Pascual Torres, Noemí Vidal, Manel Portero-Otín, Gloria Arque, Francisco Purroy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Senescent cells are capable of expressing a myriad of inflammatory cytokines and this pro-inflammatory phenomenon is known as senescence-associated secretory phenotype (SASP). The contribution of this phenomenon in brain ischemia was scarce.
Externí odkaz:
https://doaj.org/article/a33a8c378f5e40299a096dfba4c3232c
Autor:
Francisco Purroy, Mikel Vicente-Pascual, Gloria Arque, Robert Begue, Joan Farre, Yhovany Gallego, Maria Pilar Gil-Villar, Gerard Mauri, Nuria Montalà, Cristina Pereira, Coral Torres-Querol, Daniel Vazquez-Justes
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundTransient ischemic attack (TIA) provides a unique opportunity to optimize secondary preventive treatments to avoid subsequent ischemic stroke (SIS). Although atrial fibrillation (AF) is the leading cause of cardioembolism in IS and anticoag
Externí odkaz:
https://doaj.org/article/c9d2a21595364a1c9a366cb59317e26d
Autor:
Francisco Purroy, Cristina García, Gerard Mauri, Cristina Pereira, Coral Torres, Daniel Vazquez-Justes, Mikel Vicente-Pascual, Ana Vena, Gloria Arque
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Remote ischemic conditioning during cerebral ischemia (remote ischemic perconditioning, RIPerC) refers to the application of several cycles of brief ischemia and reperfusion (I/R) commonly to a limb, and it represents a new paradi
Externí odkaz:
https://doaj.org/article/9bbce54c11424144b2cac9cdf6fa4816
Autor:
Francisco Purroy, Enric Sánchez, Albert Lecube, Gloria Arqué, Mikel Vicente-Pascual, Gerard Mauri-Capdevila, Núria Torreguitart, Marta Hernández, Ferrán Barbé, Elvira Fernández, Reinald Pamplona, Cristina Farràs, Dídac Mauricio, Marcelino Bermúdez-López, the ILERVAS project, José Manuel Valdivielso, Serafí Cambray, Eva Castro, Montserrat Martínez-Alonso, Manuel Portero-otín, Mariona Jové, Ferran Rius, Jessica González, Silvia Barril, Gerard Torres, Pere Godoy, Eva Miquel, Marta Ortega, Esmeralda Castelblanco, Josep Franch-Nadal
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background: Little is known about the prevalence of cerebral microangiopathy (CM), which is related to cognitive impairment, in an asymptomatic population. Pulsatility index (PI) is an easily measurable parameter of cerebral vascular resistance in tr
Externí odkaz:
https://doaj.org/article/0ba309dcdfd4489fa8c0dee7016e106b
Autor:
Francisco Purroy, Gloria Arqué
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252351 (2021)
BackgroundCOVID-19 may predispose to both venous and arterial thromboembolism event (TEE). Reports on the prevalence and prognosis of thrombotic complications are still emerging.ObjectiveTo describe the rate of TEE complications and its influence in
Externí odkaz:
https://doaj.org/article/22293e66340b4886a61ce8d0c55b280a
Autor:
Laura Colàs-Campàs, Joan Farre, Gerard Mauri-Capdevila, Jessica Molina-Seguín, Núria Aymerich, Ángel Ois, Jaume Roquer, Silvia Tur, María del Carmen García-Carreira, Joan Martí-Fàbregas, Antonio Cruz-Culebras, Tomás Segura, Gloria Arque, Francisco Purroy
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Introduction: Ischemic tolerance (IT) refers to a state where cells are resistant to the damaging effects caused by periods of ischemia. In a clinical scenario, the IT phenomenon would be activated by a recent transient ischemic attack (TIA) before a
Externí odkaz:
https://doaj.org/article/02b8ab2adb0d467ebf1996a5327166fe
Autor:
Francisco Purroy, Gloria Arque, Gerard Mauri, Cristina García-Vázquez, Mikel Vicente-Pascual, Cristina Pereira, Daniel Vazquez-Justes, Coral Torres-Querol, Ana Vena, Sònia Abilleira, Pere Cardona, Carles Forné, Xavier Jiménez-Fàbrega, Jorge Pagola, Manuel Portero-Otin, Ana Rodríguez-Campello, Àlex Rovira, Joan Martí-Fàbregas
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Rationale: Remote ischemic perconditioning during cerebral ischemia (RIPerC) refers to the application of brief episodes of transient limb ischemia commonly to a limb, it represents a new safe, simple and low-cost paradigm in neuroprotection.Aim and/
Externí odkaz:
https://doaj.org/article/364aefab01c14f929d764e40e390b00b