Upregulated hypoxia inducible factor 1α signaling pathway in high risk myelodysplastic syndrome and acute myeloid leukemia patients is associated with better response to 5-azacytidine—data from the Hellenic myelodysplastic syndrome study group

Autor: Mpakou, V. Spathis, A. Bouchla, A. Tsakiraki, Z. Kontsioti, F. Papageorgiou, S. Bazani, E. Gkontopoulos, K. Thomopoulos, T. Glezou, I. Galanopoulos, A. Symeonidis, A. Diamantopoulos, P.T. Viniou, N.-A. Kontandreopoulou, C.-N. Zafeiropoulou, K. Kotsianidis, I. Lamprianidou, E. Foukas, P. Mpamias, A. Pappa, V.

5-azacytidine (5-AZA) is considered the standard of care for patients with high-risk myelodysplastic syndromes (MDS) and patients with acute myeloid leukemia (AML) not candidate for intensive chemotherapy. However, even after an initial favorable res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::1206d9f5cc654034239adfb0095cbb0f
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3119883

mRNA overexpression of the hypoxia inducible factor 1 alpha subunit gene (HIF1A): An independent predictor of poor overall survival in chronic lymphocytic leukemia

Autor: Kontos, C.K. Papageorgiou, S.G. Diamantopoulos, M.A. Scorilas, A. Bazani, E. Vasilatou, D. Gkontopoulos, K. Glezou, E. Stavroulaki, G. Dimitriadis, G. Pappa, V.

The hypoxia inducible factor 1 (HIF1) is a heterodimeric transcription factor that ultimately regulates cellular responses to changes in oxygen tension. In this study, we examined the potential diagnostic and prognostic potential of the mRNA expressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::475e8cd18a0db047fa6f3f0a7408800b
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086359

Apoptosis induction and gene expression profile alterations of cutaneous T-cell lymphoma cells following their exposure to bortezomib and methotrexate

Autor: Mpakou, V. Papadavid, E. Kontsioti, F. Konsta, E. Vikentiou, M. Spathis, A. Papageorgiou, S. Vasilatou, D. Gkontopoulos, K. Mpazani, E. Karakitsos, P. Rigopoulos, D. Dimitriadis, G. Pappa, V.

Mycosis fungoides (MF) and its leukemic variant Sézary syndrome (SS) comprise the majority of CTCL, a heterogenous group of non-Hodgkins lymphomas involving the skin. The CTCL's resistance to chemotherapy and the lack of full understanding of their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::0b26b5a9cd9ce3f28e4f1b60e8e0ac83
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3056740

Upregulated hypoxia inducible factor 1α signaling pathway in high risk myelodysplastic syndrome and acute myeloid leukemia patients is associated with better response to 5-azacytidine-data from the Hellenic myelodysplastic syndrome study group.

Autor: Mpakou V; Second Department of Internal Medicine and Research Institute, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece., Spathis A; Second Department of Pathology, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece., Bouchla A; Second Department of Internal Medicine and Research Institute, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece., Tsakiraki Z; Second Department of Pathology, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece., Kontsioti F; Second Department of Internal Medicine and Research Institute, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece., Papageorgiou S; Second Department of Internal Medicine and Research Institute, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece., Bazani E; Second Department of Internal Medicine and Research Institute, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece., Gkontopoulos K; Second Department of Internal Medicine and Research Institute, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece., Thomopoulos T; Second Department of Internal Medicine and Research Institute, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece., Glezou I; Second Department of Internal Medicine and Research Institute, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece., Galanopoulos A; Department of Clinical Hematology, G. Gennimatas District General Hospital, Athens, Greece.; The Hellenic MDS Study Group, Hellenic Society of Haematology, Athens, Greece., Symeonidis A; The Hellenic MDS Study Group, Hellenic Society of Haematology, Athens, Greece.; Hematology Division, Dept of Int. Medicine, University of Patras Medical School, Patras, Greece., Diamantopoulos PT; First Department of Internal Medicine, Hematology Unit, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece., Viniou NA; The Hellenic MDS Study Group, Hellenic Society of Haematology, Athens, Greece.; First Department of Internal Medicine, Hematology Unit, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece., Kontandreopoulou CN; First Department of Internal Medicine, Hematology Unit, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece., Zafeiropoulou K; Hematology Division, Dept of Int. Medicine, University of Patras Medical School, Patras, Greece., Kotsianidis I; The Hellenic MDS Study Group, Hellenic Society of Haematology, Athens, Greece.; Department of Hematology, Democritus University of Thrace, Medical School, Alexandroupolis, Greece., Lamprianidou E; Department of Hematology, Democritus University of Thrace, Medical School, Alexandroupolis, Greece., Foukas P; Second Department of Pathology, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece., Mpamias A; Second Department of Internal Medicine and Research Institute, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece., Pappa V; Second Department of Internal Medicine and Research Institute, National and Kapodistrian University of Athens, Attikon University General Hospital, Athens, Greece.; The Hellenic MDS Study Group, Hellenic Society of Haematology, Athens, Greece.

Publikováno v: Hematological oncology [Hematol Oncol] 2021 Apr; Vol. 39 (2), pp. 231-242. Date of Electronic Publication: 2021 Jan 01.

Discontinuation of the renin-angiotensin system inhibitors improves erythropoiesis in patients with lower-risk myelodysplastic syndromes.

Autor: Pavlidis G; 2nd Department of Internal Medicine - Propaedeutic and Research Unit, National and Kapodistrian University of Athens, Medical School, University General Hospital 'Attikon', Athens, Greece., Papageorgiou SG; 2nd Department of Internal Medicine - Propaedeutic and Research Unit, National and Kapodistrian University of Athens, Medical School, University General Hospital 'Attikon', 1 Rimini St., Haidari, Athens, 12462, Greece., Bazani E; 2nd Department of Internal Medicine - Propaedeutic and Research Unit, National and Kapodistrian University of Athens, Medical School, University General Hospital 'Attikon', Athens, Greece., Bouchla A; 2nd Department of Internal Medicine - Propaedeutic and Research Unit, National and Kapodistrian University of Athens, Medical School, University General Hospital 'Attikon', Athens, Greece., Glezou E; 2nd Department of Internal Medicine - Propaedeutic and Research Unit, National and Kapodistrian University of Athens, Medical School, University General Hospital 'Attikon', Athens, Greece., Gkontopoulos K; 2nd Department of Internal Medicine - Propaedeutic and Research Unit, National and Kapodistrian University of Athens, Medical School, University General Hospital 'Attikon', Athens, Greece., Thomopoulos T; 2nd Department of Internal Medicine - Propaedeutic and Research Unit, National and Kapodistrian University of Athens, Medical School, University General Hospital 'Attikon', Athens, Greece., Pappa V; 2nd Department of Internal Medicine - Propaedeutic and Research Unit, National and Kapodistrian University of Athens, Medical School, University General Hospital 'Attikon', Athens, Greece., Vlahakos DV; 2nd Department of Internal Medicine - Propaedeutic and Research Unit, National and Kapodistrian University of Athens, Medical School, University General Hospital 'Attikon', Athens, Greece.

Publikováno v: Therapeutic advances in hematology [Ther Adv Hematol] 2021 Jan 13; Vol. 12, pp. 2040620720958299. Date of Electronic Publication: 2021 Jan 13 (Print Publication: 2021).