Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Gjertrud Skorstad"'
Autor:
Sudhir Kumar Chauhan, Claire Dunn, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Gjertrud Skorstad, Adam Sike, Bjørnar Gilje, Sunil Xavier Raj, Kanutte Huse, Bjørn Naume, Jon Amund Kyte
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-17 (2024)
Abstract Immunotherapies blocking the PD-1/PD-L1 checkpoint show some efficacy in metastatic breast cancer (mBC) but are often hindered by immunosuppressive mechanisms. Understanding these mechanisms is crucial for personalized treatments, with perip
Externí odkaz:
https://doaj.org/article/21138a5be7fa4ef6868ac4e8d5f2a5bf
Autor:
Yixin Jin, Claire Dunn, Irene Persiconi, Adam Sike, Gjertrud Skorstad, Carole Beck, Jon Amund Kyte
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10024 (2024)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/37db334a9fb249e9a1ff9d1aca2b2e75
Autor:
Yixin Jin, Claire Dunn, Irene Persiconi, Adam Sike, Gjertrud Skorstad, Carole Beck, Jon Amund Kyte
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 586 (2024)
We have developed a chimeric antigen receptor (CAR) against the six-transmembrane epithelial antigen of prostate-1 (STEAP1), which is expressed in prostate cancer, Ewing sarcoma, and other malignancies. In the present study, we investigated the effec
Externí odkaz:
https://doaj.org/article/a629e6a06cd2429d8ab78ab7f593e619
Autor:
Even Walseng, Hakan Köksal, Ibrahim M. Sektioglu, Anne Fåne, Gjertrud Skorstad, Gunnar Kvalheim, Gustav Gaudernack, Else Marit Inderberg, Sébastien Wälchli
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Effector T cells equipped with engineered antigen receptors specific for cancer targets have proven to be very efficient. Two methods have emerged: the Chimeric Antigen Receptors (CARs) and T-cell Receptor (TCR) redirection. Although very po
Externí odkaz:
https://doaj.org/article/0e8a6236e1d04796a5c036d02bcd1d20
Autor:
June Helen Myklebust, Oddmund Bakke, Grethe Elisabeth Stenvik, Nadia Mensali, Lars Egil Fallang, Cinzia Progida, Anne Fåne, Gunnar Kvalheim, Gjertrud Skorstad, Else Marit Inderberg, Sébastien Wälchli, Morten P. Oksvold
Publikováno v:
Cancer Immunology, Immunotherapy. 67:525-536
Adoptive cell therapy with T-cell receptor (TCR)-engineered T cells represents a powerful method to redirect the immune system against tumours. However, although TCR recognition is restricted to a specific peptide-MHC (pMHC) complex, increasing numbe
Autor:
Ibrahim M. Sektioglu, Else Marit Inderberg, Gjertrud Skorstad, Anne Fåne, Even Walseng, Gunnar Kvalheim, Sébastien Wälchli, Hakan Köksal, Gustav Gaudernack
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports
Effector T cells equipped with engineered antigen receptors specific for cancer targets have proven to be very efficient. Two methods have emerged: the Chimeric Antigen Receptors (CARs) and T-cell Receptor (TCR) redirection. Although very potent, CAR
Autor:
Svein Dueland, Wolfgang Lilleby, Iris Bigalke, Anne Merete Aaland Tryggestad, Grete S Andreassen, Lisbeth Skoge, Dag Josefsen, Ulrika Axcrona, Steinar Aamadal, Jens A L Jørgensen, Gjertrud Skorstad, Bjørn Brennhovd, Lena Tjeldhorn, Karol Axcrona, Lene Mowinckel, Gunnar Kvalheim, Stein Saeboe-Larsen, T Kirsti Hønnåshagen
Publikováno v:
Cancer Research. 78:CT016-CT016
Prostate cancer patients diagnosed with high Gleason score (≥ 8) and large tumors (≥T2c) are considered high-risk patients and >50% will develop an early biochemical relapse following radical surgery. Presently, there is no curative therapy avail
Publikováno v:
Clinical Neurology and Neurosurgery. 111:708-712
We present a 67-year-old non-diabetic male who presented with muscle cramps, paresis, atrophy and fasciculations in the left leg, followed by rapidly progressive muscle stiffness and superimposed spasms which subsequently also affected the right leg
Publikováno v:
European Journal of Neurology. 16:1124-1129
Background: Intrathecal synthesis of oligoclonal IgG antibodies against measles virus (MeV), varicella zoster virus (VZV) and herpes simplex virus type-1 (HSV-1) is a characteristic feature multiple sclerosis (MS). Methods: We have used isoelectric f
Publikováno v:
Journal of Autoimmunity. 32:125-132
CD4 + T cells specific for immunologic non-self determinants on self-IgG, idiotopes (Id), can be raised from cerebrospinal fluid (CSF) and blood of patients with multiple sclerosis (MS). To test if Id-specific CD4 + T cells have the potential to dest