High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130

Autor: Ld, Ward, Gj, Howlett, Discolo G, Yasukawa K, Hammacher A, Rl, Moritz, Richard Simpson

Publikováno v: Europe PubMed Central

The high affinity human interleukin-6 (IL-6) receptor complex consists of IL-6 and two membrane-associated receptor components, the IL-6 receptor (alpha-subunit) and the high affinity converter and signal transducing molecule, gp-130 (beta-subunit).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::adcc99a89f56b0766736318a7e42263c
https://pubmed.ncbi.nlm.nih.gov/8083235

Studies on polydisperse systems using an air-driven ultracentrifuge: application to phosphatidylcholine vesicles

Autor: GR Eagle, RG Clarke, GJ Howlett

Publikováno v: Australian journal of biological sciences. 32(2)

A high-speed air-driven ultracentrifuge (Airfuge) has been used to determine the molecular weight and effective specific volume of phosphatidylcholine vesicles. The method used to determine the effective specific volume involved varying the solution

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b2fbac2144f06faf61b27d103a0420
https://pubmed.ncbi.nlm.nih.gov/496736

Polymorphism in disease-related apolipoprotein C-II amyloid fibrils: a structural model for rod-like fibrils.

Autor: Zlatic CO; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Vic., Australia.; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Vic., Australia., Mao Y; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Vic., Australia.; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Vic., Australia., Todorova N; School of Engineering, RMIT University, Melbourne, Vic., Australia., Mok YF; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Vic., Australia.; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Vic., Australia., Howlett GJ; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Vic., Australia.; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Vic., Australia., Yarovsky I; School of Engineering, RMIT University, Melbourne, Vic., Australia., Gooley PR; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Vic., Australia.; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Vic., Australia., Griffin MDW; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Vic., Australia.; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Vic., Australia.

Publikováno v: The FEBS journal [FEBS J] 2018 Aug; Vol. 285 (15), pp. 2799-2812. Date of Electronic Publication: 2018 Jun 09.

Solution Conditions Affect the Ability of the K30D Mutation To Prevent Amyloid Fibril Formation by Apolipoprotein C-II: Insights from Experiments and Theoretical Simulations.

Autor: Mao Y; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , Parkville, Victoria 3010, Australia., Todorova N; School of Engineering, RMIT University , GPO Box 2476V, Melbourne, Victoria 3001, Australia., Zlatic CO; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , Parkville, Victoria 3010, Australia., Gooley PR; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , Parkville, Victoria 3010, Australia., Griffin MD; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , Parkville, Victoria 3010, Australia., Howlett GJ; Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , Parkville, Victoria 3010, Australia., Yarovsky I; School of Engineering, RMIT University , GPO Box 2476V, Melbourne, Victoria 3001, Australia.

Publikováno v: Biochemistry [Biochemistry] 2016 Jul 12; Vol. 55 (27), pp. 3815-24. Date of Electronic Publication: 2016 Jun 29.

Chameleon 'aggregation-prone' segments of apoA-I: A model of amyloid fibrils formed in apoA-I amyloidosis.

Autor: Louros NN; Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 157 01, Greece., Tsiolaki PL; Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 157 01, Greece., Griffin MD; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3010, Australia., Howlett GJ; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3010, Australia., Hamodrakas SJ; Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 157 01, Greece., Iconomidou VA; Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, Athens 157 01, Greece. Electronic address: veconom@biol.uoa.gr.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2015 Aug; Vol. 79, pp. 711-8. Date of Electronic Publication: 2015 Jun 03.