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Atiprimod induce apoptosis in pituitary adenoma: Endoplasmic reticulum stress and autophagy pathways
Autor:
Pınar Obakan-Yerlikaya, Ajda Coker-Gurkan, Narcin Palavan-Unsal, Gizem Keceloglu, Burcu Ayhan-Sahin, Elif Damla Arisan
Publikováno v:
Journal of cellular biochemistry. 120(12)
Pituitary adenoma is the most common tumor with a high recurrence rate due to a hormone-dependent JAK/signal transducer and activator of transcriptions (STAT) signaling. Atiprimod, a novel compound belonging to the azaspirane class of cationic amphip