Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Gizem Efe"'
Autor:
Rafaela Muniz de Queiroz, Gizem Efe, Asja Guzman, Naoko Hashimoto, Yusuke Kawashima, Tomoaki Tanaka, Anil K. Rustgi, Carol Prives
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Although the E3 ligase Mdm2 and its homologue and binding partner MdmX are the major regulators of the p53 tumor suppressor protein, it is now evident that Mdm2 and MdmX have multiple functions that do not involve p53. As one example, it is
Externí odkaz:
https://doaj.org/article/6c7075f8b8934d2fa532d7c44cb97399
Autor:
Kyung-Pil Ko, Shengzhe Zhang, Yuanjian Huang, Bongjun Kim, Gengyi Zou, Sohee Jun, Jie Zhang, Yahui Zhao, Cecilia Martin, Karen J. Dunbar, Gizem Efe, Anil K. Rustgi, Hiroshi Nakagawa, Haiyang Zhang, Zhihua Liu, Jae-Il Park
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109795- (2024)
Summary: Despite the promising outcomes of immune checkpoint inhibitors (ICIs), resistance to ICI presents a new challenge. Therefore, selecting patients for specific ICI applications is crucial for maximizing therapeutic efficacy. Herein, we curated
Externí odkaz:
https://doaj.org/article/b0c57a6133c14aa2a1408bad70cd2bfc
Autor:
Karen J. Dunbar, Tatiana A. Karakasheva, Qiaosi Tang, Gizem Efe, Eric W. Lin, Michael Harris, Varun Sahu, Uma M. Sachdeva, Jianhua Hu, Andres J. Klein-Szanto, Brian Henick, J. Alan Diehl, Hiroshi Nakagawa, Anil K. Rustgi
Publikováno v:
Molecular Cancer Research. :OF1-OF12
Cancer-associated fibroblasts (CAF) can promote tumor growth, metastasis, and therapeutic resistance in esophageal squamous cell carcinoma (ESCC), but the mechanisms of action remain elusive. Our objective was to identify secreted factor(s) that medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d797a0ee7e68f1d658b45f17b45a616e
https://doi.org/10.1158/1541-7786.mcr-22-0872
https://doi.org/10.1158/1541-7786.mcr-22-0872
Autor:
Rafaela Muniz de Queiroz, Gizem Efe, Asja Guzman, Naoko Hashimoto, Yusuke Kawashima, Tomoaki Tanaka, Anil K Rustgi, Carol Prives
SummaryAlthough the E3 ligase Mdm2 and its homologue and binding partner MdmX are the major regulators of the p53 tumor suppressor protein, it is now evident that Mdm2 and MdmX have multiple functions that are independent of p53. For example, Mdm2 ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6738147ec9bd60f7d85d4bcaac2e9162
https://doi.org/10.1101/2023.05.08.539890
https://doi.org/10.1101/2023.05.08.539890
Autor:
Anil K. Rustgi, Hiroshi Nakagawa, J. Alan Diehl, Brian Henick, Andres J. Klein-Szanto, Jianhua Hu, Uma M. Sachdeva, Varun Sahu, Michael Harris, Eric W. Lin, Gizem Efe, Qiaosi Tang, Tatiana A. Karakasheva, Karen J. Dunbar
Targeted CCR5 inhibition replicates CCL5 loss with reduced tumor cell proliferation in vitro and in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7a3d3e670567eb8f1f072c3d48d8f7
https://doi.org/10.1158/1541-7786.22700254
https://doi.org/10.1158/1541-7786.22700254
Autor:
Anil K. Rustgi, Hiroshi Nakagawa, J. Alan Diehl, Brian Henick, Andres J. Klein-Szanto, Jianhua Hu, Uma M. Sachdeva, Varun Sahu, Michael Harris, Eric W. Lin, Gizem Efe, Qiaosi Tang, Tatiana A. Karakasheva, Karen J. Dunbar
ERK1/2 signaling pathway in CCL5 knockout cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0933bb1734d9093ebae053c064ff7727
https://doi.org/10.1158/1541-7786.22700257
https://doi.org/10.1158/1541-7786.22700257
Autor:
Anil K. Rustgi, Hiroshi Nakagawa, J. Alan Diehl, Brian Henick, Andres J. Klein-Szanto, Jianhua Hu, Uma M. Sachdeva, Varun Sahu, Michael Harris, Eric W. Lin, Gizem Efe, Qiaosi Tang, Tatiana A. Karakasheva, Karen J. Dunbar
Loss of tumor-derived CCL5 reduces tumor cell proliferation in TE-1 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce5da3b6e41b4c3241494e7d8a6d482
https://doi.org/10.1158/1541-7786.22700260
https://doi.org/10.1158/1541-7786.22700260
Autor:
Anil K. Rustgi, Hiroshi Nakagawa, J. Alan Diehl, Brian Henick, Andres J. Klein-Szanto, Jianhua Hu, Uma M. Sachdeva, Varun Sahu, Michael Harris, Eric W. Lin, Gizem Efe, Qiaosi Tang, Tatiana A. Karakasheva, Karen J. Dunbar
Supplementary Figure Legends 1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4fc845773602170d8f1371eb13a554
https://doi.org/10.1158/1541-7786.22700251
https://doi.org/10.1158/1541-7786.22700251
Autor:
Anil K. Rustgi, Hiroshi Nakagawa, J. Alan Diehl, Brian Henick, Andres J. Klein-Szanto, Jianhua Hu, Uma M. Sachdeva, Varun Sahu, Michael Harris, Eric W. Lin, Gizem Efe, Qiaosi Tang, Tatiana A. Karakasheva, Karen J. Dunbar
Cancer-associated fibroblasts (CAF) can promote tumor growth, metastasis, and therapeutic resistance in esophageal squamous cell carcinoma (ESCC), but the mechanisms of action remain elusive. Our objective was to identify secreted factor(s) that medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea27b6630d56cd1b5ec63faa125b304
https://doi.org/10.1158/1541-7786.c.6618025.v1
https://doi.org/10.1158/1541-7786.c.6618025.v1
Autor:
Anil K. Rustgi, Hiroshi Nakagawa, J. Alan Diehl, Brian Henick, Andres J. Klein-Szanto, Jianhua Hu, Uma M. Sachdeva, Varun Sahu, Michael Harris, Eric W. Lin, Gizem Efe, Qiaosi Tang, Tatiana A. Karakasheva, Karen J. Dunbar
Confirmation of CCL5 knockout clones.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0526ec0b3f1605d9ccb18deee2704f1c
https://doi.org/10.1158/1541-7786.22700263.v1
https://doi.org/10.1158/1541-7786.22700263.v1