Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Giyoung Jung"'
Autor:
Jason Qian, Lorena Lyon, Zhi-xiang Lu, Han-Ying Jhuang, Kole Sedlack, Pamela A. Silver, Michael H. Baym, Fernando H. Ramírez-Guadiana, Michael Springer, Lior Artzi, David Z. Rudner, Mohammad Arammash, Rocío del Carmen Barajas-Ornelas, Sarah A. Boswell, Christopher P. Mancuso, Victoria Jones, Michael Melfi, Ahmad S. Khalil, Akhila Sonti, Siân V. Owen, Mary E. Pettit, Giyoung Jung
Publikováno v:
Science. 368:1135-1140
DNA barcodes in small packages Under adverse environmental conditions, some microorganisms form spores that provide robust protection for genetic material. Qian et al. developed a system in which DNA barcodes are encapsulated inside nongerminating mi
Fate of the M-phase-assembled centrioles during the cell cycle in the TP53;PCNT;CEP215-deleted cells
Autor:
Giyoung Jung, K. Rhee
Cancer cells frequently include supernumerary centrioles. Here, we generated TP53;PCNT;CEP215 triple knockout cell lines and observed precocious separation and amplification of the centrioles at M phase. Many of the triple KO cells maintained supernu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfd2c6ea4338e23e1fa900ed2932cf68
https://doi.org/10.1101/2020.09.14.297440
https://doi.org/10.1101/2020.09.14.297440
Autor:
Jason Qian, Mohammad Arammash, Siân V. Owen, Lorena Lyon, Han-Ying Jhuang, Giyoung Jung, Sarah A. Boswell, David Z. Rudner, Fernando H. Ramírez-Guadiana, Michael Melfi, Kole Sedlack, Pamela A. Silver, Michael H. Baym, Rocío del Carmen Barajas-Ornelas, Michael Springer, Ahmad S. Khalil, Akhila Sonti, Lior Artzi, Zhi-xiang Lu, Christopher P. Mancuso, Victoria Jones
Mapping where an object has been is a fundamental challenge for human health, commerce, and food safety. Location-specific microbes offers the potential to cheaply and sensitively determine object provenance. We created a synthetic, scalable microbia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63e4050aea5f1cc1a583b07b206bec5
https://doi.org/10.1101/2020.03.14.990804
https://doi.org/10.1101/2020.03.14.990804
Autor:
Jungha Park, Hansaem Jeong, Eun Seo Lee, Giyoung Jung, Kyung Ha Ryu, Hyukjin Lee, Byeongmoon Jeong, Nathaniel S. Hwang
Publikováno v:
Journal of Biomedical Nanotechnology. 12:1023-1034
The development of efficient and safe gene delivery carriers has been a major challenge in the clinical application of non-viral gene therapy. Herein, we report novel bioreducible poly(amido amine)s for the efficient delivery of genetic material such
Autor:
Richard J. Cornell, Leonid Gaidukov, Jonathan L. Lyles, Jeffrey K. Marshall, Bruno Figueroa, Bhanu Chandra Mulukutla, Nevin M. Summers, An-Hsiang Adam Chu, Timothy K. Lu, Paul Sakorafas, Michelle M Chang, Ron Weiss, Madhuresh Sumit, John J. Scarcelli, Giyoung Jung, Douglas A. Lauffenburger, Boriana Tzvetkova, Wen Allen Tseng, Kaffa Cote, Sepideh Dolatshahi
Publikováno v:
Nature chemical biology. 15(7)
N-linked glycosylation in monoclonal antibodies (mAbs) is crucial for structural and functional properties of mAb therapeutics, including stability, pharmacokinetics, safety and clinical efficacy. The biopharmaceutical industry currently lacks tools
Autor:
Jicong Cao, Giyoung Jung, Fahim Farzadfard, Timothy K. Lu, Yasutomi Higashikuni, Nava Gharaei
Publikováno v:
Mol Cell
PMC
PMC
Computing and memory in living cells are central to encoding next-generation therapies and studying in situ biology, but existing strategies have limited encoding capacity and are challenging to scale. To overcome this bottleneck, we developed a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3425490db15df8ca8bfe2fac892e16ff
Autor:
Kisuk Yang, Hyukjin Lee, Ji-Yong Kim, Hyunuk Ro, Giyoung Jung, Nathaniel S. Hwang, Hyun Gu Yim, Seung Woo Cho, Jungha Park
Publikováno v:
Cell and Tissue Research. 362:115-126
Transient cartilage and a mineralizing microenvironment play pivotal roles in mesenchymal cell ossification during bone formation. In order to recreate these microenvironmental cues, C3H10T1/2 murine mesenchymal stem cells (MSCs) were exposed to chon
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 103:1258-1266
Extracellular matrix (ECM) components such as fibronectin (FN) and laminin (LMN) play prominent roles in controlling cellular behaviors. Many attempts have been made to explore cellular behaviors on combinatorial ECM arrays in high-throughput systems
Autor:
Eunjee Lee, Nathaniel S. Hwang, Michael P. Verzi, Mitchel S. Devita, Anant Madabhushi, Sanjay Chahar, Anthony Kulesa, Satish Viswanath, Paul P. Shao, Prabhas V. Moghe, Joseph J. Kim, Erin P. Childers, Shichong Liu, Neal K. Bennett, Matthew L. Becker, Benjamin A. Garcia, Giyoung Jung
Publikováno v:
Scientific Reports
While distinct stem cell phenotypes follow global changes in chromatin marks, single-cell chromatin technologies are unable to resolve or predict stem cell fates. We propose the first such use of optical high content nanoscopy of histone epigenetic m
Publikováno v:
Archives of Pharmacal Research. 37:120-128
Magnetic nanoparticles have been subjected to extensive studies in the past few decades owing to their promising potentials in biomedical applications. The versatile intrinsic properties of magnetic nanoparticles enable their use in many biomedical a