Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Giusy Battilana"'
Autor:
Alessandro Gandin, Yaswanth Murugesan, Veronica Torresan, Lorenzo Ulliana, Anna Citron, Paolo Contessotto, Giusy Battilana, Tito Panciera, Maurizio Ventre, A. Paolo Netti, Lucia Nicola, Stefano Piccolo, Giovanna Brusatin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract In spite of tremendous advances made in the comprehension of mechanotransduction, implementation of mechanobiology assays remains challenging for the broad community of cell biologists. Hydrogel substrates with tunable stiffness are essentia
Externí odkaz:
https://doaj.org/article/92689fff4621487898791648086db563
Publikováno v:
Cell Stress, Vol 5, Iss 11, Pp 167-172 (2021)
Dysregulated gene expression is intrinsic to cell transformation, tumorigenesis and metastasis. Cancer-specific gene-expression profiles stem from gene regulatory networks fueled by genetic and epigenetic defects, and by abnormal signals of the tumor
Externí odkaz:
https://doaj.org/article/ac6ce0f89c8c428b9d8a78c173961d16
Autor:
Antonio Totaro, Martina Castellan, Giusy Battilana, Francesca Zanconato, Luca Azzolin, Stefano Giulitti, Michelangelo Cordenonsi, Stefano Piccolo
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Notch signalling is a fundamental negative regulator of epidermal stemness. Here, the authors show that cell mechanics through YAP/TAZ activity prevent primary human keratinocytes from differentiating by inhibiting cell-autonomous Notch signals.
Externí odkaz:
https://doaj.org/article/594670e97aba451c8912bf09316bfecd
Autor:
Hanna Lucie Sladitschek-Martens, Alberto Guarnieri, Giulia Brumana, Francesca Zanconato, Giusy Battilana, Romy Lucon Xiccato, Tito Panciera, Mattia Forcato, Silvio Bicciato, Vincenza Guzzardo, Matteo Fassan, Lorenzo Ulliana, Alessandro Gandin, Claudio Tripodo, Marco Foiani, Giovanna Brusatin, Michelangelo Cordenonsi, Stefano Piccolo
Publikováno v:
Nature
Ageing is intimately connected to the induction of cell senescence(1,2), but why this is so remains poorly understood. A key challenge isthe identification of pathways that normally suppress senescence, are lost during ageing and are functionally rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a71447a79893da8786689a416fb9d8
http://hdl.handle.net/11577/3457458
http://hdl.handle.net/11577/3457458
Autor:
Marco Schiavone, Elena Rampazzo, Alessandro Casari, Giusy Battilana, Luca Persano, Enrico Moro, Shu Liu, Steve D. Leach, Natascia Tiso, Francesco Argenton
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 7, Pp 883-894 (2014)
Pancreatic adenocarcinoma, one of the worst malignancies of the exocrine pancreas, is a solid tumor with increasing incidence and mortality in industrialized countries. This condition is usually driven by oncogenic KRAS point mutations and evolves in
Externí odkaz:
https://doaj.org/article/97164d1965eb48629a8ca60691ca70c9
Autor:
Giulia Brumana, Qiuyu Zhuang, Giovanna Brusatin, Giusy Battilana, Tito Panciera, Alessandro Gandin, Stefano Piccolo, Luca Azzolin, Antonio Totaro, Michelangelo Cordenonsi
Publikováno v:
Proceedings of the National Academy of Sciences
Autophagy, besides ensuring energy metabolism and organelle renewal, is crucial for the biology of adult normal and cancer stem cells. However, it remains incompletely understood how autophagy connects to stemness factors and the nature of the microe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a2c91c02ddfd52a70b8c6ae3c75828
https://doi.org/10.1073/pnas.1908228116
https://doi.org/10.1073/pnas.1908228116
Autor:
Giusy Battilana, Elena Porcù, Oriana Romano, Silvio Bicciato, Francesca Zanconato, Antonio Rosato, Andrea Grilli, Paolo Contessotto, Alberto Guarnieri, Hanna L. Sladitschek, Anna Citron, Stefano Piccolo, Michelangelo Cordenonsi, Matteo Fassan, Martina Castellan, Tito Panciera, Atsushi Fujimura
Publikováno v:
Nature Cancer
Nature cancer
Nature cancer
Glioblastoma (GBM) is a devastating human malignancy. GBM stem-like cells (GSCs) drive tumor initiation and progression. Yet, the molecular determinants defining GSCs in their native state in patients remain poorly understood. Here we used single cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa128a31ad5913634eddadafdfd885dc
https://hdl.handle.net/11380/1226230
https://hdl.handle.net/11380/1226230
Autor:
Pascale Lejeune, Francesca Zanconato, Andrea Manfrin, Erika Quaranta, Daniele Di Biagio, Vincenza Guzzardo, Letizia Filippi, Bernard Haendler, Luca Azzolin, Jeroen Krijgsveld, Mattia Forcato, Giusy Battilana, Michelangelo Cordenonsi, Gianluca Sigismondo, Silvio Bicciato, Stefano Piccolo, Matteo Fassan
Publikováno v:
Nature medicine
Nature Medicine
Nature Medicine
Cancer cells rely on dysregulated gene expression. This establishes specific transcriptional addictions that may be therapeutically exploited. Yet, the mechanisms that are ultimately responsible for these addictions are poorly understood. Here, we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbda4280e43d60f4758fa2b4bd6e3cc2
https://doi.org/10.1038/s41591-018-0158-8
https://doi.org/10.1038/s41591-018-0158-8
Autor:
Romy Lucon Xiccato, Daniele Di Biagio, Giusy Battilana, Francesca Zanconato, Tito Panciera, Michelangelo Cordenonsi, Luca Azzolin, Lei Chang, Mariaceleste Aragona, Stefano Piccolo
Publikováno v:
Molecular Cancer Research. 18:B39-B39
Inactivation of ARID1A and other components of the nuclear SWI/SNF protein complex occurs at very high frequencies in a variety of human malignancies, suggesting a widespread role for the SWI/SNF complex in tumor suppression. However, the underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::639d85f7f4b094b8395f5a4918d9f30a
https://doi.org/10.1158/1557-3125.hippo19-b39
https://doi.org/10.1158/1557-3125.hippo19-b39
Autor:
Shu Liu, Giusy Battilana, Francesco Argenton, Elena Rampazzo, A. Casari, Luca Persano, Marco Schiavone, Steven D. Leach, Natascia Tiso, Enrico Moro
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 7, Pp 883-894 (2014)
Disease Models & Mechanisms
Disease Models & Mechanisms
Pancreatic adenocarcinoma, one of the worst malignancies of exocrine pancreas, is a solid tumor with increasing incidence and mortality in industrialized countries. It is usually driven by oncogenic Kras point mutations and evolves into a highly aggr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5faff4580de28edb4ac9e30362d22aad
http://dmm.biologists.org/content/7/7/883
http://dmm.biologists.org/content/7/7/883