Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Giusy, Tassone"'
Autor:
Giusy Tassone, Samuele Maramai, Marco Paolino, Stefania Lamponi, Federica Poggialini, Elena Dreassi, Elena Petricci, Stefano Alcaro, Cecilia Pozzi, Isabella Romeo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Bioconjugation is one of the most promising strategies to improve drug delivery, especially in cancer therapy. Biomolecules such as bile acids (BAs) have been intensively explored as carriers, due to their peculiar physicochemical properties
Externí odkaz:
https://doaj.org/article/1a4c84aa763544cdb95cf8741a3df437
Autor:
Fernanda A. H. Batista, Sérgio L. Ramos, Giusy Tassone, Andrei Leitão, Carlos A. Montanari, Maurizio Botta, Mattia Mori, Júlio C. Borges
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 639-649 (2020)
Leishmaniasis is a neglected disease caused by the protozoa Leishmania ssp. Environmental differences found by the parasites in the vector and the host are translated into cellular stress, leading to the production of heat shock proteins (Hsp). These
Externí odkaz:
https://doaj.org/article/1eb2af2ab0394a7fb2e4c0e33e4550a4
Publikováno v:
Pharmaceuticals, Vol 15, Iss 11, p 1341 (2022)
Protozoan parasites are responsible for several harmful and widespread human diseases that cause high morbidity and mortality. Currently available treatments have serious limitations due to poor efficiency, strong adverse effects, and high cost. Henc
Externí odkaz:
https://doaj.org/article/0a1703002fc6475aa5cadd2be35ba060
Autor:
Leire Iralde-Lorente, Ylenia Cau, Letizia Clementi, Lorenzo Franci, Giusy Tassone, Daniela Valensin, Mattia Mori, Adriano Angelucci, Mario Chiariello, Maurizio Botta
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 657-664 (2019)
14-3-3 are regulatory proteins that through protein–protein interactions (PPI) with numerous binding partners could be involved in several human diseases, including cancer, neurodegenerative disorders, and pathogens infections. Following our resear
Externí odkaz:
https://doaj.org/article/0387ca67151143d8bee11b1f00a12246
Autor:
Cecilia Pozzi, Anne Vanet, Valeria Francesconi, Lorenzo Tagliazucchi, Giusy Tassone, Alberto Venturelli, Francesca Spyrakis, Marco Mazzorana, Maria P. Costi, Michele Tonelli
Publikováno v:
Journal of Medicinal Chemistry. 66:3664-3702
Autor:
Giusy Tassone, Giacomo Landi, Pasquale Linciano, Valeria Francesconi, Michele Tonelli, Lorenzo Tagliazucchi, Maria Paola Costi, Stefano Mangani, Cecilia Pozzi
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 636 (2021)
Trypanosoma and Leishmania parasites are the etiological agents of various threatening neglected tropical diseases (NTDs), including human African trypanosomiasis (HAT), Chagas disease, and various types of leishmaniasis. Recently, meaningful progres
Externí odkaz:
https://doaj.org/article/70e738fa89394bc7959ea50a78f26d41
Publikováno v:
Biomolecules, Vol 11, Iss 5, p 645 (2021)
Bile acids (BAs) are hydroxylated steroids derived from cholesterol that act at the intestinal level to facilitate the absorption of several nutrients and also play a role as signaling molecules. In the liver of various vertebrates, the trafficking o
Externí odkaz:
https://doaj.org/article/d5db4fcd2e504a6caad565d05fa00249
Publikováno v:
Life, Vol 11, Iss 5, p 386 (2021)
Alzheimer’s disease (AD) is a neurodegenerative disorder, affecting millions of people worldwide, a number expected to exponentially increase in the future since no effective treatments are available so far. AD is characterized by severe cognitive
Externí odkaz:
https://doaj.org/article/dff3f3a72ab240d8b1f6e83dd722a5ea
Autor:
Stefano Barbera, Luisa Raucci, Giusy Tassone, Laura Tinti, Filippo Prischi, Annalisa Santucci, Maurizio Mongiat, Gian Marco Tosi, Federico Galvagni, Anna Dimberg, Cecilia Pozzi, Maurizio Orlandini
Blocking the signaling activated by the plasma membrane receptor CD93 has recently been demonstrated a useful tool in antiangiogenic treatment and oncotherapy. In the proliferating endothelium, CD93 regulates cell adhesion, migration, and vascular ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f3700b815f6fef4799b8898cc0e175
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-495880
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-495880
Publikováno v:
European Journal of Organic Chemistry. 2022